(22 nodes) Signaling by PTK6 network (Anopheles darlingi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_008414	Putative ras-related gtpase. (189 aa)
	AND_006533	ELMO domain-containing protein 2. (323 aa)
	AND_006094	Cbl-d. (182 aa)
	AND_006445	Ral. (201 aa)
	AND_006536	Ubiquitin. (78 aa)
	AND_007698	Crk. (278 aa)
	AND_006534	Ubiquitin-5E. (154 aa)
	AND_006215	Ubiquitin/60S ribosomal protein L40 fusion. (128 aa)
	AND_010648	Ral. (186 aa)
	AND_008881	Cold shock domain-containing protein E1. (957 aa)
	AND_000781	Uncharacterized protein. (209 aa)
	AND_000661	Leucine-rich repeat kinase. (2818 aa)
	AND_002044	Engulfment and cell motility protein. (722 aa)
	AND_002916	Gtpase rho. (313 aa)
	AND_002935	Rho GTPase-activating protein 5. (1840 aa)
	AND_004544	Cysteine-rich protein. (179 aa)
	AND_003988	KxDL domain-containing protein. (247 aa)
	AND_004030	Paxillin. (230 aa)
	AND_006146	Quaking related 54B. (392 aa)
	AND_006369	Dedicator of cytokinesis protein 1; Belongs to the DOCK family. (2090 aa)
	AND_004971	Ras gtpase activating protein. (955 aa)
	AND_009204	Ubiquitin. (77 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000661	AND_000781	W5JTR7	W5JWM6	Leucine-rich repeat kinase.	Uncharacterized protein.	0.993
AND_000661	AND_002044	W5JTR7	W5JP59	Leucine-rich repeat kinase.	Engulfment and cell motility protein.	0.539
AND_000661	AND_002916	W5JTR7	W5JME1	Leucine-rich repeat kinase.	Gtpase rho.	0.937
AND_000661	AND_002935	W5JTR7	W5JMC7	Leucine-rich repeat kinase.	Rho GTPase-activating protein 5.	0.552
AND_000661	AND_003988	W5JTR7	W5JJF4	Leucine-rich repeat kinase.	KxDL domain-containing protein.	0.452
AND_000661	AND_004030	W5JTR7	W5JIM0	Leucine-rich repeat kinase.	Paxillin.	0.636
AND_000661	AND_004544	W5JTR7	W5JLF5	Leucine-rich repeat kinase.	Cysteine-rich protein.	0.636
AND_000661	AND_004971	W5JTR7	W5JG12	Leucine-rich repeat kinase.	Ras gtpase activating protein.	0.697
AND_000661	AND_006094	W5JTR7	W5JFU8	Leucine-rich repeat kinase.	Cbl-d.	0.902
AND_000661	AND_006146	W5JTR7	W5JH71	Leucine-rich repeat kinase.	Quaking related 54B.	0.587
AND_000661	AND_006215	W5JTR7	B6DDR1	Leucine-rich repeat kinase.	Ubiquitin/60S ribosomal protein L40 fusion.	0.992
AND_000661	AND_006369	W5JTR7	W5JGN7	Leucine-rich repeat kinase.	Dedicator of cytokinesis protein 1; Belongs to the DOCK family.	0.621
AND_000661	AND_006445	W5JTR7	W5JEW5	Leucine-rich repeat kinase.	Ral.	0.934
AND_000661	AND_006534	W5JTR7	W5JEN8	Leucine-rich repeat kinase.	Ubiquitin-5E.	0.992
AND_000661	AND_006536	W5JTR7	W5JCI8	Leucine-rich repeat kinase.	Ubiquitin.	0.993
AND_000661	AND_007698	W5JTR7	W5JCS8	Leucine-rich repeat kinase.	Crk.	0.806
AND_000661	AND_008414	W5JTR7	W5JB40	Leucine-rich repeat kinase.	Putative ras-related gtpase.	0.934
AND_000661	AND_008881	W5JTR7	W5J6A3	Leucine-rich repeat kinase.	Cold shock domain-containing protein E1.	0.934
AND_000661	AND_009204	W5JTR7	W5J8K3	Leucine-rich repeat kinase.	Ubiquitin.	0.992
AND_000661	AND_010648	W5JTR7	W5J225	Leucine-rich repeat kinase.	Ral.	0.934