50 items (Anopheles darlingi) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_001151	NADH ubiquinone dehydrogenase. (83 aa)
	COX1	Cytochrome c oxidase subunit 1; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B. (512 aa)
	COX2	Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (228 aa)
	COX3	Cytochrome c oxidase subunit 3; Subunits I, II and III form the functional core of the enzyme complex. (262 aa)
	AND_010660	Prip interacting protein, pimt. (1098 aa)
	AND_010642	Bicoid stability factor. (1433 aa)
	AND_009977	Cytochrome c proximal; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (108 aa)
	AND_008707	Histone deacetylase; Belongs to the histone deacetylase family. HD Type 1 subfamily. (432 aa)
	AND_008216	Lethal 87Df. (125 aa)
	AND_009892	Heme oxygenase; Heme oxygenase cleaves the heme ring at the alpha methene bridge to form biliverdin. Biliverdin is subsequently converted to bilirubin by biliverdin reductase. (248 aa)
	AND_009227	Cystinosin. (275 aa)
	AND_009744	NAD(P)-bd_dom domain-containing protein. (202 aa)
	AND_009049	Cytochrome c oxidase polypeptide. (157 aa)
	AND_009297	Uncharacterized protein. (168 aa)
	AND_008155	Sin3b. (2132 aa)
	AND_008035	Uncharacterized protein. (69 aa)
	AND_008563	Retinoid x receptor (Rxr). (561 aa)
	AND_007190	Cytochrome c oxidase assembly protein COX11, mitochondrial. (232 aa)
	AND_006683	Inner membrane protein COX18, mitochondrial. (333 aa)
	AND_008240	Uncharacterized protein. (4309 aa)
	AND_007054	Mitochondrial cytochrome c oxidase subunit VIC. (79 aa)
	AND_005978	Cytochrome c oxidase subunit; This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport. (76 aa)
	AND_006938	Zinc finger protein. (67 aa)
	AND_005976	Uncharacterized protein. (423 aa)
	AND_006810	Cytochrome c oxidase, subunit VB. (119 aa)
	AND_006444	SCO1, mitochondrial. (274 aa)
	AND_004152	Putative desumoylating isopeptidase 2. (203 aa)
	AND_002980	P160 coactivator FISC. (2091 aa)
	AND_003841	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (667 aa)
	AND_004213	Allergen; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (161 aa)
	AND_004004	Brg-1 associated factor. (508 aa)
	AND_003811	Putative cytochrome c oxidase subunit 7A, mitochondrial. (74 aa)
	AND_003756	Brg-1 associated factor. (536 aa)
	AND_003732	Wd-repeat protein. (504 aa)
	AND_003448	Uncharacterized protein. (284 aa)
	AND_002957	SANT domain-containing protein. (678 aa)
	AND_003168	Nuclear receptor subfamily 1 group D member 3. (1143 aa)
	AND_001572	Helicase ATP-binding domain-containing protein. (1203 aa)
	AND_002534	Signal peptide peptidase. (401 aa)
	AND_001347	SURF1-like protein; Probably involved in the biogenesis of the COX complex. Belongs to the SURF1 family. (289 aa)
	AND_002864	Cytochrome c oxidase assembly protein COX19. (132 aa)
	AND_002747	Cytochrome c oxidase subunit VIIa. (89 aa)
	AND_001813	Cytochrome c oxidase, subunit VIA; Belongs to the cytochrome c oxidase subunit 6A family. (148 aa)
	AND_000450	DNA-binding protein smubp-2. (652 aa)
	AND_001263	Med1 domain-containing protein. (2224 aa)
	AND_001542	Uncharacterized protein. (150 aa)
	AND_000036	Signal peptide peptidase. (145 aa)
	AND_001456	Cytochrome c oxidase subunit iv. (202 aa)
	AND_000035	Uncharacterized protein. (217 aa)
	AND_000189	Uncharacterized protein. (315 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_000035	AND_000036	W5JWP2	W5JUU9	Uncharacterized protein.	Signal peptide peptidase.	0.895
AND_000036	AND_000035	W5JUU9	W5JWP2	Signal peptide peptidase.	Uncharacterized protein.	0.895
AND_000450	AND_001263	W5JUC5	W5JUJ1	DNA-binding protein smubp-2.	Med1 domain-containing protein.	0.469
AND_000450	AND_001542	W5JUC5	W5JUN3	DNA-binding protein smubp-2.	Uncharacterized protein.	0.486
AND_000450	AND_002957	W5JUC5	W5JPP2	DNA-binding protein smubp-2.	SANT domain-containing protein.	0.505
AND_000450	AND_002980	W5JUC5	W5JM79	DNA-binding protein smubp-2.	P160 coactivator FISC.	0.456
AND_000450	AND_003168	W5JUC5	W5JQ89	DNA-binding protein smubp-2.	Nuclear receptor subfamily 1 group D member 3.	0.414
AND_000450	AND_003448	W5JUC5	W5JPI8	DNA-binding protein smubp-2.	Uncharacterized protein.	0.414
AND_000450	AND_003756	W5JUC5	W5JNN0	DNA-binding protein smubp-2.	Brg-1 associated factor.	0.453
AND_000450	AND_003841	W5JUC5	W5JMA0	DNA-binding protein smubp-2.	Histone-arginine methyltransferase CARM1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	0.489
AND_000450	AND_004004	W5JUC5	W5JNB0	DNA-binding protein smubp-2.	Brg-1 associated factor.	0.453
AND_000450	AND_008240	W5JUC5	W5JBB5	DNA-binding protein smubp-2.	Uncharacterized protein.	0.561
AND_000450	AND_008563	W5JUC5	W5JAL7	DNA-binding protein smubp-2.	Retinoid x receptor (Rxr).	0.451
AND_000450	AND_009297	W5JUC5	W5J8L4	DNA-binding protein smubp-2.	Uncharacterized protein.	0.459
AND_000450	AND_010660	W5JUC5	W5J203	DNA-binding protein smubp-2.	Prip interacting protein, pimt.	0.459
AND_001151	AND_001456	B6DDV9	W5JUY3	NADH ubiquinone dehydrogenase.	Cytochrome c oxidase subunit iv.	0.959
AND_001151	AND_001813	B6DDV9	W5JT15	NADH ubiquinone dehydrogenase.	Cytochrome c oxidase, subunit VIA; Belongs to the cytochrome c oxidase subunit 6A family.	0.944
AND_001151	AND_002747	B6DDV9	W5JRX5	NADH ubiquinone dehydrogenase.	Cytochrome c oxidase subunit VIIa.	0.969
AND_001151	AND_003811	B6DDV9	W5JNJ4	NADH ubiquinone dehydrogenase.	Putative cytochrome c oxidase subunit 7A, mitochondrial.	0.770
AND_001151	AND_005976	B6DDV9	W5JE49	NADH ubiquinone dehydrogenase.	Uncharacterized protein.	0.908