(9 nodes) JAB/MPN domain network (Anopheles darlingi)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AND_002522	26S proteasome regulatory subunit 7, psd7. (338 aa)
	AND_008191	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (334 aa)
	AND_008431	Putative 26s proteasome regulatory complex subunit rpn11. (311 aa)
	AND_010444	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (287 aa)
	AND_004235	Amsh. (421 aa)
	AND_006389	MPN domain-containing protein. (1600 aa)
	AND_010477	Pre-mrna splicing factor prp8. (2386 aa)
	AND_005014	Signalosome subunit. (366 aa)
	AND_004563	Jun activation domain binding protein. (338 aa)

Your Current Organism:

Anopheles darlingi

NCBI taxonomy Id: 43151
Other names: A. darlingi, American malaria mosquito, Anopheles paulistensis, Nyssorhynchus darlingi

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AND_002522	AND_004563	W5JMV0	W5JK74	26S proteasome regulatory subunit 7, psd7.	Jun activation domain binding protein.	0.895
AND_002522	AND_005014	W5JMV0	W5JK60	26S proteasome regulatory subunit 7, psd7.	Signalosome subunit.	0.407
AND_002522	AND_006389	W5JMV0	W5JD15	26S proteasome regulatory subunit 7, psd7.	MPN domain-containing protein.	0.994
AND_002522	AND_008191	W5JMV0	W5JBH2	26S proteasome regulatory subunit 7, psd7.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.932
AND_002522	AND_008431	W5JMV0	W5J7L3	26S proteasome regulatory subunit 7, psd7.	Putative 26s proteasome regulatory complex subunit rpn11.	0.999
AND_004235	AND_004563	W5JIT6	W5JK74	Amsh.	Jun activation domain binding protein.	0.474
AND_004235	AND_008191	W5JIT6	W5JBH2	Amsh.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.883
AND_004563	AND_002522	W5JK74	W5JMV0	Jun activation domain binding protein.	26S proteasome regulatory subunit 7, psd7.	0.895
AND_004563	AND_004235	W5JK74	W5JIT6	Jun activation domain binding protein.	Amsh.	0.474
AND_004563	AND_005014	W5JK74	W5JK60	Jun activation domain binding protein.	Signalosome subunit.	0.999
AND_004563	AND_006389	W5JK74	W5JD15	Jun activation domain binding protein.	MPN domain-containing protein.	0.495
AND_004563	AND_008191	W5JK74	W5JBH2	Jun activation domain binding protein.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.920
AND_004563	AND_008431	W5JK74	W5J7L3	Jun activation domain binding protein.	Putative 26s proteasome regulatory complex subunit rpn11.	0.691
AND_004563	AND_010444	W5JK74	W5J565	Jun activation domain binding protein.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.723
AND_004563	AND_010477	W5JK74	W5J1B3	Jun activation domain binding protein.	Pre-mrna splicing factor prp8.	0.419
AND_005014	AND_002522	W5JK60	W5JMV0	Signalosome subunit.	26S proteasome regulatory subunit 7, psd7.	0.407
AND_005014	AND_004563	W5JK60	W5JK74	Signalosome subunit.	Jun activation domain binding protein.	0.999
AND_005014	AND_008191	W5JK60	W5JBH2	Signalosome subunit.	Eukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.920
AND_005014	AND_008431	W5JK60	W5J7L3	Signalosome subunit.	Putative 26s proteasome regulatory complex subunit rpn11.	0.503
AND_005014	AND_010444	W5JK60	W5J565	Signalosome subunit.	Eukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation.	0.428