STRINGSTRING
FGG FGG TMPRSS11D TMPRSS11D SPINT1 SPINT1 LOC101965973 LOC101965973 SERPINE1 SERPINE1 Klk8 Klk8 KLK4 KLK4 PROS1 PROS1 C1QBP C1QBP TMPRSS4 TMPRSS4 KLK14 KLK14 F3 F3 F2 F2 SERPINF2 SERPINF2 KLK6 KLK6 SPINK4 SPINK4 SERPINB5 SERPINB5 SERPINB11 SERPINB11 SERPINB7 SERPINB7 ABCB11 ABCB11 SERPINB2 SERPINB2 TMPRSS13 TMPRSS13 LOC101960778 LOC101960778 F2R F2R I3MBK1_ICTTR I3MBK1_ICTTR TMPRSS11F TMPRSS11F F5 F5 GC GC A2M A2M AHSG AHSG SERPINE2 SERPINE2 PLAT PLAT KLKB1 KLKB1 F11 F11 SPINK1 SPINK1 ST14 ST14 TFPI TFPI FGB FGB F9 F9 TMPRSS15 TMPRSS15 SPINK6 SPINK6 Pinlyp Pinlyp PROCR PROCR PROC PROC HRG HRG LOC101976419 LOC101976419 TMPRSS2 TMPRSS2 LOC101959979 LOC101959979 KLK5 KLK5 LOC101959666 LOC101959666 LOC101974544 LOC101974544 MST1 MST1 SSC4D SSC4D LOC101967274 LOC101967274 I3MMN9_ICTTR I3MMN9_ICTTR SPINT2 SPINT2 SERPIND1 SERPIND1 SERPINC1 SERPINC1 LOC101972849 LOC101972849 LOC101976399 LOC101976399 VTN VTN PRSS22 PRSS22 LOC101977084 LOC101977084 HPN HPN APOA5 APOA5 SERPINB1 SERPINB1 TMPRSS11E TMPRSS11E LOC101957774 LOC101957774 KLK12 KLK12 LOC101973046 LOC101973046 LOC101957938 LOC101957938 LOC101973215 LOC101973215 KNG1 KNG1 SLPI SLPI LOC101976153 LOC101976153 LOC101957374 LOC101957374 LOC101977364 LOC101977364 LOC101978189 LOC101978189 LOC101971994 LOC101971994 SERPINB10 SERPINB10 F8 F8 F10 F10 Prss46p Prss46p LOC101960226 LOC101960226 F7 F7 F2RL1 F2RL1 Sspo Sspo ELANE ELANE LOC101968603 LOC101968603 KLK10 KLK10 LOC101966300 LOC101966300 FGA FGA KLK15 KLK15 TFPI2 TFPI2 KLK7 KLK7 LOC101966003 LOC101966003 PLG PLG LOC101975297 LOC101975297 TMPRSS12 TMPRSS12 LOC101977635 LOC101977635 LOC101966592 LOC101966592 PRSS36 PRSS36 ENSSTOP00000026488 ENSSTOP00000026488 LOC101955219 LOC101955219 F2RL2 F2RL2 PRSS8 PRSS8 SPINK7 SPINK7 LOC101969188 LOC101969188 Prss50 Prss50 KLK11 KLK11 HPX HPX SERPINB8 SERPINB8 PLAU PLAU
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGGFibrinogen gamma chain. (445 aa)
TMPRSS11DTransmembrane protease serine; Belongs to the peptidase S1 family. (419 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (510 aa)
LOC101965973Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (279 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
Klk8Peptidase S1 domain-containing protein. (139 aa)
KLK4Kallikrein related peptidase 4; Belongs to the peptidase S1 family. (255 aa)
PROS1Protein S. (674 aa)
C1QBPComplement C1q binding protein. (281 aa)
TMPRSS4Transmembrane serine protease 4; Belongs to the peptidase S1 family. (402 aa)
KLK14Kallikrein related peptidase 14; Belongs to the peptidase S1 family. (251 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (293 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
SERPINF2Serpin family F member 2; Belongs to the serpin family. (417 aa)
KLK6Kallikrein related peptidase 6; Belongs to the peptidase S1 family. (247 aa)
SPINK4Serine peptidase inhibitor, Kazal type 4. (86 aa)
SERPINB5Serpin family B member 5; Belongs to the serpin family. (378 aa)
SERPINB11Serpin family B member 11 (gene/pseudogene); Belongs to the serpin family. (392 aa)
SERPINB7Serpin family B member 7; Belongs to the serpin family. (363 aa)
ABCB11ATP binding cassette subfamily B member 11. (1321 aa)
SERPINB2Serpin family B member 2; Belongs to the serpin family. (415 aa)
TMPRSS13Transmembrane serine protease 13; Belongs to the peptidase S1 family. (552 aa)
LOC101960778Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
F2RCoagulation factor II thrombin receptor; Belongs to the G-protein coupled receptor 1 family. (427 aa)
I3MBK1_ICTTRPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (299 aa)
TMPRSS11FTransmembrane protease serine; Belongs to the peptidase S1 family. (438 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (2114 aa)
GCGC vitamin D binding protein. (482 aa)
A2MAlpha-2-macroglobulin. (1463 aa)
AHSGAlpha 2-HS glycoprotein. (348 aa)
SERPINE2Serpin family E member 2; Belongs to the serpin family. (397 aa)
PLATPlasminogen activator; Belongs to the peptidase S1 family. (560 aa)
KLKB1Kallikrein B1; Belongs to the peptidase S1 family. (637 aa)
F11Coagulation factor XI; Belongs to the peptidase S1 family. (617 aa)
SPINK1Serine peptidase inhibitor, Kazal type 1. (68 aa)
ST14Suppressor of tumorigenicity 14 protein homolog; Degrades extracellular matrix. Belongs to the peptidase S1 family. (855 aa)
TFPITissue factor pathway inhibitor. (301 aa)
FGBFibrinogen beta chain. (478 aa)
F9Coagulation factor IX. (463 aa)
TMPRSS15Transmembrane serine protease 15; Belongs to the peptidase S1 family. (1019 aa)
SPINK6Serine peptidase inhibitor, Kazal type 6. (97 aa)
PinlypUncharacterized protein. (212 aa)
PROCRProtein C receptor. (242 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (460 aa)
HRGHistidine rich glycoprotein. (531 aa)
LOC101976419Lipocln_cytosolic_FA-bd_dom domain-containing protein. (216 aa)
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (531 aa)
LOC101959979SERPIN domain-containing protein; Belongs to the serpin family. (386 aa)
KLK5Kallikrein related peptidase 5; Belongs to the peptidase S1 family. (293 aa)
LOC101959666Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (261 aa)
LOC101974544Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (253 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (715 aa)
SSC4DScavenger receptor cysteine rich family member with 4 domains. (510 aa)
LOC101967274SERPIN domain-containing protein; Belongs to the serpin family. (375 aa)
I3MMN9_ICTTRSERPIN domain-containing protein; Belongs to the serpin family. (417 aa)
SPINT2Serine peptidase inhibitor, Kunitz type 2. (252 aa)
SERPIND1Serpin family D member 1; Belongs to the serpin family. (478 aa)
SERPINC1Serpin family C member 1; Belongs to the serpin family. (465 aa)
LOC101972849SERPIN domain-containing protein; Belongs to the serpin family. (412 aa)
LOC101976399SERPIN domain-containing protein; Belongs to the serpin family. (410 aa)
VTNSMB domain-containing protein. (466 aa)
PRSS22Serine protease 22; Belongs to the peptidase S1 family. (318 aa)
LOC101977084Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (244 aa)
HPNHepsin; Belongs to the peptidase S1 family. (417 aa)
APOA5Apolipoprotein A5. (370 aa)
SERPINB1Serpin family B member 1; Belongs to the serpin family. (379 aa)
TMPRSS11ETransmembrane protease serine; Belongs to the peptidase S1 family. (422 aa)
LOC101957774Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (286 aa)
KLK12Kallikrein related peptidase 12; Belongs to the peptidase S1 family. (248 aa)
LOC101973046Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC101957938SERPIN domain-containing protein; Belongs to the serpin family. (377 aa)
LOC101973215SERPIN domain-containing protein; Belongs to the serpin family. (375 aa)
KNG1Kininogen 1. (651 aa)
SLPISecretory leukocyte peptidase inhibitor. (133 aa)
LOC101976153Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC101957374SERPIN domain-containing protein; Belongs to the serpin family. (427 aa)
LOC101977364Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (255 aa)
LOC101978189Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (252 aa)
LOC101971994SERPIN domain-containing protein; Belongs to the serpin family. (379 aa)
SERPINB10Serpin family B member 10; Belongs to the serpin family. (397 aa)
F8Coagulation factor VIII; Belongs to the multicopper oxidase family. (2226 aa)
F10Coagulation factor X. (483 aa)
Prss46pPeptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (300 aa)
LOC101960226Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (316 aa)
F7Coagulation factor VII; Belongs to the peptidase S1 family. (375 aa)
F2RL1F2R like trypsin receptor 1. (397 aa)
SspoSCO-spondin. (4969 aa)
ELANEElastase, neutrophil expressed; Belongs to the peptidase S1 family. (266 aa)
LOC101968603Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (180 aa)
KLK10Kallikrein related peptidase 10; Belongs to the peptidase S1 family. (248 aa)
LOC101966300Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
FGAFibrinogen alpha chain. (788 aa)
KLK15Kallikrein related peptidase 15; Belongs to the peptidase S1 family. (255 aa)
TFPI2Tissue factor pathway inhibitor. (234 aa)
KLK7Kallikrein related peptidase 7; Belongs to the peptidase S1 family. (249 aa)
LOC101966003Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (247 aa)
PLGPlasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...] (794 aa)
LOC101975297Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (267 aa)
TMPRSS12Transmembrane serine protease 12; Belongs to the peptidase S1 family. (349 aa)
LOC101977635Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (255 aa)
LOC101966592Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (246 aa)
PRSS36Polyserase-2; Serine protease. Has a preference for substrates with an Arg instead of a Lys residue in position P1. (849 aa)
ENSSTOP00000026488Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (263 aa)
LOC101955219Uncharacterized protein. (612 aa)
F2RL2Coagulation factor II thrombin receptor like 2; Belongs to the G-protein coupled receptor 1 family. (371 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (342 aa)
SPINK7Serine peptidase inhibitor, Kazal type 7 (putative). (71 aa)
LOC101969188SERPIN domain-containing protein; Belongs to the serpin family. (225 aa)
Prss50Peptidase S1 domain-containing protein. (403 aa)
KLK11Kallikrein related peptidase 11; Belongs to the peptidase S1 family. (282 aa)
HPXHemopexin; Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. (462 aa)
SERPINB8Serpin family B member 8; Belongs to the serpin family. (374 aa)
PLAUPlasminogen activator, urokinase. (424 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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