STRINGSTRING
RCL1 RCL1 DIS3 DIS3 GNL3 GNL3 EMG1 EMG1 DDX56 DDX56 ZNF622 ZNF622 NOB1 NOB1 RRP15 RRP15 UTP23 UTP23 NAT10 NAT10 GCC1 GCC1 RBM28 RBM28 NOP9 NOP9 WDR46 WDR46 AATF AATF RRP9 RRP9 DDX52 DDX52 EXOSC4 EXOSC4 NGDN NGDN RBM34 RBM34 RRP7A RRP7A IMP4 IMP4 WDR3 WDR3 KRR1 KRR1 DDX27 DDX27 NOL11 NOL11 ZCCHC17 ZCCHC17 DDX54 DDX54 NSUN2 NSUN2 NSUN6 NSUN6 EBNA1BP2 EBNA1BP2 MPHOSPH10 MPHOSPH10 GNL2 GNL2 DDX24 DDX24 NOL10 NOL10 EXOSC7 EXOSC7 DDX55 DDX55 NOP58 NOP58 NLE1 NLE1 RRP12 RRP12 RIOK2 RIOK2 DDX49 DDX49 HEATR1 HEATR1 KRI1 KRI1 Pa2g4 Pa2g4 MAK16 MAK16 NSA2 NSA2 EXOSC9 EXOSC9 DDX31 DDX31 DCAF13 DCAF13 FCF1 FCF1 Utp14a Utp14a RPF1 RPF1 DIS3L DIS3L RIOK1 RIOK1 SNU13 SNU13 PUM3 PUM3 BRIX1 BRIX1 IPO7 IPO7 NOP14 NOP14 EXOSC3 EXOSC3 NOC2L NOC2L Gtpbp4 Gtpbp4 DDX18 DDX18 MTREX MTREX LOC101961182 LOC101961182 RRP1 RRP1 RRP1B RRP1B GNL1 GNL1 TSR1 TSR1 FBL FBL NOP56 NOP56 DIMT1 DIMT1 Ltv1 Ltv1 TBL3 TBL3 WDR75 WDR75 PES1 PES1 Pwp2 Pwp2 PDCD11 PDCD11 WDR36 WDR36 WDR43 WDR43 BMS1 BMS1 RSL1D1 RSL1D1 NOL6 NOL6 UTP6 UTP6 UTP4 UTP4 UTP20 UTP20 UTP25 UTP25 NIFK NIFK GRWD1 GRWD1 BYSL BYSL Nol12 Nol12 UTP15 UTP15 DDX47 DDX47 PWP1 PWP1 METTL27 METTL27 Mphosph6 Mphosph6 UTP11 UTP11 P2RY11 P2RY11 I3N0G8_ICTTR I3N0G8_ICTTR RPF2 RPF2 ZNF593 ZNF593 FAM207A FAM207A UTP3 UTP3 CEBPZ CEBPZ NOP53 NOP53 GNL3L GNL3L PNO1 PNO1 DNTTIP2 DNTTIP2 Lyar Lyar NOC3L NOC3L EXOSC5 EXOSC5 WDR74 WDR74 EXOSC6 EXOSC6 RRS1 RRS1 RPS6 RPS6 SURF6 SURF6 MRTO4 MRTO4 NOC4L NOC4L PAK1IP1 PAK1IP1 ENSSTOP00000024161 ENSSTOP00000024161 ENSSTOP00000025355 ENSSTOP00000025355 ENSSTOP00000025407 ENSSTOP00000025407 Exosc8 Exosc8 ENSSTOP00000026334 ENSSTOP00000026334 IMP3 IMP3 NMD3 NMD3 ENSSTOP00000026589 ENSSTOP00000026589 NIP7 NIP7 LSG1 LSG1 C1D C1D FTSJ3 FTSJ3 LOC101967904 LOC101967904 EXOSC10 EXOSC10 DHX37 DHX37 LOC101967696 LOC101967696 EXOSC1 EXOSC1 Rtca Rtca ENSSTOP00000029275 ENSSTOP00000029275 LOC101957349 LOC101957349 UTP18 UTP18 BUD23 BUD23 ENSSTOP00000031055 ENSSTOP00000031055 WDR17 WDR17 EXOSC2 EXOSC2 FBLL1 FBLL1 BOP1 BOP1 RSL24D1 RSL24D1 MCC MCC WDR12 WDR12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RCL1RNA terminal phosphate cyclase like 1. (373 aa)
DIS3DIS3 homolog, exosome endoribonuclease and 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (958 aa)
GNL3G protein nucleolar 3. (546 aa)
EMG1EMG1 N1-specific pseudouridine methyltransferase. (244 aa)
DDX56DEAD-box helicase 56. (546 aa)
ZNF622Zinc finger protein 622. (477 aa)
NOB1RNA-binding protein NOB1; May play a role in mRNA degradation. Belongs to the NOB1 family. (405 aa)
RRP15Ribosomal RNA processing 15 homolog. (283 aa)
UTP23UTP23 small subunit processome component. (248 aa)
NAT10RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1026 aa)
GCC1GRIP and coiled-coil domain containing 1. (775 aa)
RBM28RNA binding motif protein 28. (766 aa)
NOP9NOP9 nucleolar protein. (642 aa)
WDR46WD repeat domain 46. (619 aa)
AATFApoptosis antagonizing transcription factor. (506 aa)
RRP9Ribosomal RNA processing 9, U3 small nucleolar RNA binding protein. (475 aa)
DDX52DExD-box helicase 52. (322 aa)
EXOSC4Exosome component 4. (246 aa)
NGDNNeuroguidin. (315 aa)
RBM34RNA binding motif protein 34. (429 aa)
RRP7ARibosomal RNA processing 7 homolog A. (280 aa)
IMP4IMP U3 small nucleolar ribonucleoprotein 4. (299 aa)
WDR3WD repeat domain 3. (943 aa)
KRR1KRR1 small subunit processome component; Required for 40S ribosome biogenesis. Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. (381 aa)
DDX27DEAD-box helicase 27; Belongs to the DEAD box helicase family. (763 aa)
NOL11Nucleolar protein 11. (710 aa)
ZCCHC17Zinc finger CCHC-type containing 17. (241 aa)
DDX54ATP-dependent RNA helicase DDX54; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (830 aa)
NSUN2NOP2/Sun RNA methyltransferase 2; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (758 aa)
NSUN6NOP2/Sun RNA methyltransferase 6; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (476 aa)
EBNA1BP2EBNA1 binding protein 2. (201 aa)
MPHOSPH10U3 small nucleolar ribonucleoprotein protein MPP10; Component of the 60-80S U3 small nucleolar ribonucleoprotein (U3 snoRNP). Required for the early cleavages during pre-18S ribosomal RNA processing; Belongs to the MPP10 family. (679 aa)
GNL2Nucleolar GTP-binding protein 2; GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation. Belongs to the TRAFAC class YlqF/YawG GTPase family. NOG2 subfamily. (731 aa)
DDX24DEAD-box helicase 24. (884 aa)
NOL10Nucleolar protein 10. (685 aa)
EXOSC7Exosome component 7. (291 aa)
DDX55RNA helicase. (600 aa)
NOP58NOP58 ribonucleoprotein. (530 aa)
NLE1Notchless homolog 1. (485 aa)
RRP12Ribosomal RNA processing 12 homolog. (1292 aa)
RIOK2RIO kinase 2. (550 aa)
DDX49DEAD-box helicase 49; Belongs to the DEAD box helicase family. (483 aa)
HEATR1HEAT repeat containing 1. (2140 aa)
KRI1KRI1 homolog. (682 aa)
Pa2g4Peptidase_M24 domain-containing protein. (394 aa)
MAK16Protein MAK16 homolog; Belongs to the MAK16 family. (298 aa)
NSA2Uncharacterized protein. (171 aa)
EXOSC9Exosome component 9. (439 aa)
DDX31RNA helicase. (681 aa)
DCAF13DDB1 and CUL4 associated factor 13. (445 aa)
FCF1PINc domain-containing protein. (199 aa)
Utp14aUncharacterized protein. (771 aa)
RPF1Ribosome production factor 1 homolog. (349 aa)
DIS3LDIS3 like exosome 3'-5' exoribonuclease; Belongs to the RNR ribonuclease family. (1007 aa)
RIOK1Serine/threonine-protein kinase RIO1; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (569 aa)
SNU13Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
PUM3Pumilio RNA binding family member 3. (647 aa)
BRIX1Biogenesis of ribosomes BRX1. (353 aa)
IPO7Importin 7. (1038 aa)
NOP14NOP14 nucleolar protein. (860 aa)
EXOSC3Exosome component 3. (275 aa)
NOC2LNOC2 like nucleolar associated transcriptional repressor. (667 aa)
Gtpbp4Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (634 aa)
DDX18RNA helicase. (654 aa)
MTREXMtr4 exosome RNA helicase. (1042 aa)
LOC101961182Brix domain-containing protein. (468 aa)
RRP1Ribosomal RNA processing 1. (422 aa)
RRP1BRibosomal RNA processing 1B. (755 aa)
GNL1G protein nucleolar 1 (putative). (606 aa)
TSR1TSR1 ribosome maturation factor. (805 aa)
FBLFibrillarin. (322 aa)
NOP56NOP56 ribonucleoprotein. (595 aa)
DIMT1rRNA adenine N(6)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. (312 aa)
Ltv1LTV1 ribosome biogenesis factor. (474 aa)
TBL3Transducin beta like 3. (800 aa)
WDR75WD repeat domain 75. (830 aa)
PES1Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. (585 aa)
Pwp2Uncharacterized protein. (923 aa)
PDCD11Programmed cell death 11. (1848 aa)
WDR36WD repeat domain 36. (1014 aa)
WDR43WD repeat domain 43. (679 aa)
BMS1BMS1 ribosome biogenesis factor. (1280 aa)
RSL1D1Ribosomal L1 domain containing 1. (417 aa)
NOL6Nucleolar protein 6. (1154 aa)
UTP6UTP6 small subunit processome component. (597 aa)
UTP4UTP4 small subunit processome component. (686 aa)
UTP20UTP20 small subunit processome component. (2790 aa)
UTP25UTP25 small subunit processor component. (756 aa)
NIFKNucleolar protein interacting with the FHA domain of MKI67. (297 aa)
GRWD1Glutamate rich WD repeat containing 1. (445 aa)
BYSLBystin like. (437 aa)
Nol12Uncharacterized protein. (215 aa)
UTP15UTP15 small subunit processome component. (527 aa)
DDX47DEAD-box helicase 47; Belongs to the DEAD box helicase family. (440 aa)
PWP1PWP1 homolog, endonuclein. (500 aa)
METTL27Methyltransferase like 27. (236 aa)
Mphosph6Uncharacterized protein. (161 aa)
UTP11U3 small nucleolar RNA-associated protein 11; Involved in nucleolar processing of pre-18S ribosomal RNA. (253 aa)
P2RY11Purinergic receptor P2Y11; Belongs to the G-protein coupled receptor 1 family. (372 aa)
I3N0G8_ICTTRRibosomal_L7Ae domain-containing protein. (116 aa)
RPF2Ribosome production factor 2 homolog. (253 aa)
ZNF593Zinc finger protein 593. (134 aa)
FAM207AFamily with sequence similarity 207 member A. (175 aa)
UTP3UTP3 small subunit processome component. (473 aa)
CEBPZCCAAT enhancer binding protein zeta. (1060 aa)
NOP53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (477 aa)
GNL3LG protein nucleolar 3 like. (576 aa)
PNO1Partner of NOB1 homolog. (248 aa)
DNTTIP2Deoxynucleotidyltransferase terminal interacting protein 2. (757 aa)
LyarUncharacterized protein. (190 aa)
NOC3LNucleolar complex protein 3 homolog. (803 aa)
EXOSC5Exosome component 5. (235 aa)
WDR74WD repeat domain 74. (385 aa)
EXOSC6Exosome component 6. (272 aa)
RRS1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (365 aa)
RPS640S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family. (219 aa)
SURF6Surfeit 6. (357 aa)
MRTO4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (239 aa)
NOC4LNucleolar complex associated 4 homolog. (515 aa)
PAK1IP1PAK1 interacting protein 1. (360 aa)
ENSSTOP00000024161Nucleolar GTP-binding protein 1; Involved in the biogenesis of the 60S ribosomal subunit. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. NOG subfamily. (626 aa)
ENSSTOP00000025355Uncharacterized protein. (127 aa)
ENSSTOP00000025407Uncharacterized protein. (163 aa)
Exosc8RNase_PH domain-containing protein. (89 aa)
ENSSTOP00000026334Uncharacterized protein. (81 aa)
IMP3IMP U3 small nucleolar ribonucleoprotein 3. (184 aa)
NMD360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (503 aa)
ENSSTOP00000026589Uncharacterized protein. (154 aa)
NIP760S ribosome subunit biogenesis protein NIP7 homolog; Required for proper 34S pre-rRNA processing and 60S ribosome subunit assembly; Belongs to the NIP7 family. (180 aa)
LSG1Large 60S subunit nuclear export GTPase 1. (533 aa)
C1DC1D nuclear receptor corepressor. (141 aa)
FTSJ3pre-rRNA processing protein FTSJ3; Probable methyltransferase involved in the processing of the 34S pre-rRNA to 18S rRNA and in 40S ribosomal subunit formation. Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. SPB1 subfamily. (837 aa)
LOC101967904Uncharacterized protein. (349 aa)
EXOSC10Exosome component 10. (886 aa)
DHX37DEAH-box helicase 37. (1184 aa)
LOC101967696DUF1726 domain-containing protein. (271 aa)
EXOSC1Exosome component 1. (195 aa)
RtcaUncharacterized protein. (353 aa)
ENSSTOP00000029275ECR1_N domain-containing protein. (121 aa)
LOC101957349Uncharacterized protein. (247 aa)
UTP18UTP18 small subunit processome component. (555 aa)
BUD23BUD23 rRNA methyltransferase and ribosome maturation factor. (281 aa)
ENSSTOP00000031055Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (79 aa)
WDR17WD repeat domain 17. (1313 aa)
EXOSC2Exosome component 2. (293 aa)
FBLL1Fibrillarin like 1. (209 aa)
BOP1Ribosome biogenesis protein BOP1; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (743 aa)
RSL24D1Ribosomal L24 domain containing 1. (163 aa)
MCCMCC regulator of WNT signaling pathway. (1019 aa)
WDR12Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. (423 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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