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SGMS1 SGMS1 SGMS2 SGMS2 UGCG UGCG ACER1 ACER1 GBA2 GBA2 CERS2 CERS2 GBA GBA SMPD1 SMPD1 CERKL CERKL SMPD3 SMPD3 ASAH1 ASAH1 ASAH2 ASAH2 ACER2 ACER2 SMPD4 SMPD4 CERK CERK SMPD2 SMPD2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SGMS1Sphingomyelin synthase 1. (419 aa)
SGMS2Sphingomyelin synthase 2. (365 aa)
UGCGUDP-glucose ceramide glucosyltransferase. (394 aa)
ACER1Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (919 aa)
CERS2Ceramide synthase 2. (380 aa)
GBAGlucosylceramidase. (516 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
CERKLCeramide kinase like. (540 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
ASAH1N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa)
ASAH2Neutral ceramidase. (716 aa)
ACER2Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
SMPD4Sphingomyelin phosphodiesterase 4. (827 aa)
CERKCeramide kinase. (461 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (419 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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