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IFNGR2 IFNGR2 CSF3R CSF3R IL10RB IL10RB IL22RA1 IL22RA1 IL9R IL9R EPOR EPOR TYK2 TYK2 SOCS4 SOCS4 I3M4W8_ICTTR I3M4W8_ICTTR IL12B IL12B CSF3 CSF3 IL23R IL23R IL15 IL15 Il15ra Il15ra PIAS3 PIAS3 IL10 IL10 JAK2 JAK2 STAT5B STAT5B STAT5A STAT5A STAT3 STAT3 IL5RA IL5RA PTPN2 PTPN2 JAK3 JAK3 IL10RA IL10RA IL13 IL13 STAT1 STAT1 IL27RA IL27RA IL6R IL6R TP53BP2 TP53BP2 IL5 IL5 SOCS3 SOCS3 SOCS2 SOCS2 CRADD CRADD IL22 IL22 STAT6 STAT6 EPO EPO CSF2 CSF2 IL12A IL12A IFNG IFNG IFNAR1 IFNAR1 IL23A IL23A STAT2 STAT2 IL2 IL2 I3MQY6_ICTTR I3MQY6_ICTTR IL13RA2 IL13RA2 I3MVL6_ICTTR I3MVL6_ICTTR STAT4 STAT4 EBI3 EBI3 IFNGR1 IFNGR1 I3N090_ICTTR I3N090_ICTTR IL2RB IL2RB LOC101960206 LOC101960206 IRF9 IRF9 JAK1 JAK1 LOC101968765 LOC101968765 Ifnk Ifnk SOCS1 SOCS1 IL2RA IL2RA CISH CISH IL27 IL27 SOCS5 SOCS5 IFNLR1 IFNLR1 IL4R IL4R IL21R IL21R IL13RA1 IL13RA1 LOC101969049 LOC101969049 IL9 IL9 PIAS2 PIAS2 ENSSTOP00000028887 ENSSTOP00000028887 PIAS1 PIAS1 IL7 IL7 IL21 IL21 Ifnar2 Ifnar2 Il2rg Il2rg
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFNGR2Interferon gamma receptor 2. (306 aa)
CSF3RColony stimulating factor 3 receptor. (777 aa)
IL10RBInterleukin 10 receptor subunit beta. (334 aa)
IL22RA1Interleukin 22 receptor subunit alpha 1. (565 aa)
IL9RInterleukin 9 receptor. (465 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (509 aa)
TYK2Tyrosine-protein kinase. (1194 aa)
SOCS4Suppressor of cytokine signaling 4. (439 aa)
I3M4W8_ICTTRUncharacterized protein. (207 aa)
IL12BInterleukin-12 subunit beta; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. (327 aa)
CSF3Colony stimulating factor 3. (210 aa)
IL23RInterleukin 23 receptor. (644 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (134 aa)
Il15raSushi domain-containing protein. (309 aa)
PIAS3Protein inhibitor of activated STAT 3. (628 aa)
IL10Interleukin 10. (178 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
STAT5BSignal transducer and activator of transcription. (765 aa)
STAT5ASignal transducer and activator of transcription. (773 aa)
STAT3Signal transducer and activator of transcription. (748 aa)
IL5RAInterleukin 5 receptor subunit alpha. (417 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (389 aa)
JAK3Tyrosine-protein kinase. (1042 aa)
IL10RAInterleukin 10 receptor subunit alpha. (576 aa)
IL13Interleukin 13. (130 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
IL27RAInterleukin 27 receptor subunit alpha. (569 aa)
IL6RInterleukin 6 receptor. (409 aa)
TP53BP2Tumor protein p53 binding protein 2. (1134 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
SOCS3Suppressor of cytokine signaling 3. (227 aa)
SOCS2Suppressor of cytokine signaling 2. (159 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
IL22Interleukin 22. (179 aa)
STAT6Signal transducer and activator of transcription. (847 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
CSF2Colony stimulating factor 2. (138 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
IFNGInterferon gamma; Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. (173 aa)
IFNAR1Interferon alpha and beta receptor subunit 1. (490 aa)
IL23AInterleukin 23 subunit alpha. (185 aa)
STAT2Signal transducer and activator of transcription. (805 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
I3MQY6_ICTTRUncharacterized protein. (238 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (388 aa)
I3MVL6_ICTTRUncharacterized protein. (192 aa)
STAT4Signal transducer and activator of transcription. (758 aa)
EBI3Epstein-Barr virus induced 3. (210 aa)
IFNGR1Interferon gamma receptor 1. (476 aa)
I3N090_ICTTRUncharacterized protein. (207 aa)
IL2RBInterleukin 2 receptor subunit beta. (540 aa)
LOC101960206Uncharacterized protein. (207 aa)
IRF9Interferon regulatory factor 9. (357 aa)
JAK1Tyrosine-protein kinase. (1142 aa)
LOC101968765Uncharacterized protein. (187 aa)
IfnkUncharacterized protein. (241 aa)
SOCS1Suppressor of cytokine signaling 1. (211 aa)
IL2RAInterleukin 2 receptor subunit alpha. (251 aa)
CISHCytokine inducible SH2 containing protein. (257 aa)
IL27Interleukin 27. (240 aa)
SOCS5Suppressor of cytokine signaling 5. (536 aa)
IFNLR1Interferon lambda receptor 1. (530 aa)
IL4RInterleukin 4 receptor. (795 aa)
IL21RInterleukin 21 receptor. (516 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (424 aa)
LOC101969049Uncharacterized protein. (174 aa)
IL9Interleukin 9. (144 aa)
PIAS2Protein inhibitor of activated STAT 2. (615 aa)
ENSSTOP00000028887Uncharacterized protein. (184 aa)
PIAS1Protein inhibitor of activated STAT 1. (651 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (159 aa)
IL21Interleukin; Belongs to the IL-15/IL-21 family. (158 aa)
Ifnar2Uncharacterized protein. (516 aa)
Il2rgFibronectin type-III domain-containing protein. (374 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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