STRINGSTRING
CSF3R CSF3R EPOR EPOR CSF3 CSF3 IL15 IL15 Il15ra Il15ra JAK2 JAK2 IL5RA IL5RA IL13 IL13 IL6R IL6R IL5 IL5 EPO EPO CSF2 CSF2 IL2 IL2 IL13RA2 IL13RA2 I3MVL6_ICTTR I3MVL6_ICTTR I3N090_ICTTR I3N090_ICTTR IL2RB IL2RB LOC101960206 LOC101960206 IL2RA IL2RA IL4R IL4R IL13RA1 IL13RA1 IL7 IL7 Il2rg Il2rg
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CSF3RColony stimulating factor 3 receptor. (777 aa)
EPORErythropoietin receptor; Receptor for erythropoietin. (509 aa)
CSF3Colony stimulating factor 3. (210 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (134 aa)
Il15raSushi domain-containing protein. (309 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
IL5RAInterleukin 5 receptor subunit alpha. (417 aa)
IL13Interleukin 13. (130 aa)
IL6RInterleukin 6 receptor. (409 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (134 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
CSF2Colony stimulating factor 2. (138 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (154 aa)
IL13RA2Interleukin 13 receptor subunit alpha 2. (388 aa)
I3MVL6_ICTTRUncharacterized protein. (192 aa)
I3N090_ICTTRUncharacterized protein. (207 aa)
IL2RBInterleukin 2 receptor subunit beta. (540 aa)
LOC101960206Uncharacterized protein. (207 aa)
IL2RAInterleukin 2 receptor subunit alpha. (251 aa)
IL4RInterleukin 4 receptor. (795 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (424 aa)
IL7Interleukin-7; Hematopoietic growth factor capable of stimulating the proliferation of lymphoid progenitors. It is important for proliferation during certain stages of B-cell maturation. Belongs to the IL-7/IL-9 family. (159 aa)
Il2rgFibronectin type-III domain-containing protein. (374 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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