(5 nodes) CXCR3 chemokine receptor binding, and Negative regulation of leukocyte tethering or rolling network (Ictidomys tridecemlineatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CXCL12	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	CXCL9	C-X-C motif chemokine. (125 aa)
	LOC101954665	C-X-C motif chemokine. (106 aa)
	CCL21	C-C motif chemokine ligand 21. (133 aa)
	CXCL10	C-X-C motif chemokine. (98 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCL21	CXCL10	ENSSTOP00000018627	ENSSTOP00000023723	C-C motif chemokine ligand 21.	C-X-C motif chemokine.	0.984
CCL21	CXCL12	ENSSTOP00000018627	ENSSTOP00000005317	C-C motif chemokine ligand 21.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.989
CCL21	CXCL9	ENSSTOP00000018627	ENSSTOP00000012296	C-C motif chemokine ligand 21.	C-X-C motif chemokine.	0.985
CCL21	LOC101954665	ENSSTOP00000018627	ENSSTOP00000013361	C-C motif chemokine ligand 21.	C-X-C motif chemokine.	0.947
CXCL10	CCL21	ENSSTOP00000023723	ENSSTOP00000018627	C-X-C motif chemokine.	C-C motif chemokine ligand 21.	0.984
CXCL10	CXCL12	ENSSTOP00000023723	ENSSTOP00000005317	C-X-C motif chemokine.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.984
CXCL10	CXCL9	ENSSTOP00000023723	ENSSTOP00000012296	C-X-C motif chemokine.	C-X-C motif chemokine.	0.998
CXCL10	LOC101954665	ENSSTOP00000023723	ENSSTOP00000013361	C-X-C motif chemokine.	C-X-C motif chemokine.	0.992
CXCL12	CCL21	ENSSTOP00000005317	ENSSTOP00000018627	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	C-C motif chemokine ligand 21.	0.989
CXCL12	CXCL10	ENSSTOP00000005317	ENSSTOP00000023723	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	C-X-C motif chemokine.	0.984
CXCL12	CXCL9	ENSSTOP00000005317	ENSSTOP00000012296	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	C-X-C motif chemokine.	0.988
CXCL12	LOC101954665	ENSSTOP00000005317	ENSSTOP00000013361	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	C-X-C motif chemokine.	0.975
CXCL9	CCL21	ENSSTOP00000012296	ENSSTOP00000018627	C-X-C motif chemokine.	C-C motif chemokine ligand 21.	0.985
CXCL9	CXCL10	ENSSTOP00000012296	ENSSTOP00000023723	C-X-C motif chemokine.	C-X-C motif chemokine.	0.998
CXCL9	CXCL12	ENSSTOP00000012296	ENSSTOP00000005317	C-X-C motif chemokine.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.988
CXCL9	LOC101954665	ENSSTOP00000012296	ENSSTOP00000013361	C-X-C motif chemokine.	C-X-C motif chemokine.	0.993
LOC101954665	CCL21	ENSSTOP00000013361	ENSSTOP00000018627	C-X-C motif chemokine.	C-C motif chemokine ligand 21.	0.947
LOC101954665	CXCL10	ENSSTOP00000013361	ENSSTOP00000023723	C-X-C motif chemokine.	C-X-C motif chemokine.	0.992
LOC101954665	CXCL12	ENSSTOP00000013361	ENSSTOP00000005317	C-X-C motif chemokine.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.975
LOC101954665	CXCL9	ENSSTOP00000013361	ENSSTOP00000012296	C-X-C motif chemokine.	C-X-C motif chemokine.	0.993