STRINGSTRING
SHC1 SHC1 I3LWF9_ICTTR I3LWF9_ICTTR PIK3CB PIK3CB PIK3CG PIK3CG RRAS RRAS Pik3r2 Pik3r2 GRAP2 GRAP2 LRIG3 LRIG3 HABP2 HABP2 SHC4 SHC4 MST1R MST1R BTK BTK HCK HCK PIK3R6 PIK3R6 PIK3R5 PIK3R5 CBL CBL PLCG2 PLCG2 SYK SYK PTPN9 PTPN9 MERTK MERTK BMX BMX FYN FYN PTK6 PTK6 SRMS SRMS RRAD RRAD SASH3 SASH3 SH3GL1 SH3GL1 KHDRBS3 KHDRBS3 SVEP1 SVEP1 ITK ITK LOC101962660 LOC101962660 ILDR1 ILDR1 LRIT1 LRIT1 VAV1 VAV1 INPPL1 INPPL1 ZAP70 ZAP70 INPP5D INPP5D CD8A CD8A KHDRBS2 KHDRBS2 PLCG1 PLCG1 MATK MATK CBLB CBLB LCK LCK GRB2 GRB2 BLNK BLNK SH3GL3 SH3GL3 PIK3CA PIK3CA KHDRBS1 KHDRBS1 PTK7 PTK7 RASGRF1 RASGRF1 PTPN22 PTPN22 ILDR2 ILDR2 PAG1 PAG1 PTPN4 PTPN4 LCP2 LCP2 LOC101965906 LOC101965906 LRIT3 LRIT3 MOS MOS FGR FGR TXK TXK CD3D CD3D GAB1 GAB1 DNAAF2 DNAAF2 CLNK CLNK IRS1 IRS1 Stimate Stimate Col22a1 Col22a1 HGFAC HGFAC MET MET LRIG1 LRIG1 RRAS2 RRAS2 PTPN11 PTPN11 CD247 CD247 Fcgr2b Fcgr2b CSK CSK Mustn1 Mustn1 I3N7U1_ICTTR I3N7U1_ICTTR PTPN12 PTPN12 GRAP GRAP GAS6 GAS6 DOK2 DOK2 SAMSN1 SAMSN1 STAP2 STAP2 CD4 CD4 SH3KBP1 SH3KBP1 LOC101968118 LOC101968118 RIPK4 RIPK4 ENSSTOP00000025526 ENSSTOP00000025526 LAT LAT PIK3R1 PIK3R1 PTPRC PTPRC TEC TEC AXL AXL Pik3r3 Pik3r3 LYN LYN Pik3cd Pik3cd PTPN6 PTPN6 SOS1 SOS1 Shc2 Shc2 P3R3URF P3R3URF VAV3 VAV3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SHC1SHC adaptor protein 1. (583 aa)
I3LWF9_ICTTRSH2 domain-containing protein. (118 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1071 aa)
RRASRAS related. (218 aa)
Pik3r2Uncharacterized protein. (724 aa)
GRAP2GRB2 related adaptor protein 2. (324 aa)
LRIG3Leucine rich repeats and immunoglobulin like domains 3. (1072 aa)
HABP2Hyaluronan binding protein 2. (536 aa)
SHC4SHC adaptor protein 4. (630 aa)
MST1RMacrophage stimulating 1 receptor. (1382 aa)
BTKTyrosine-protein kinase. (659 aa)
HCKTyrosine-protein kinase. (502 aa)
PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (748 aa)
PIK3R5Phosphoinositide-3-kinase regulatory subunit 5. (871 aa)
CBLCbl proto-oncogene. (870 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
SYKTyrosine-protein kinase. (626 aa)
PTPN9Protein tyrosine phosphatase non-receptor type 9. (593 aa)
MERTKMER proto-oncogene, tyrosine kinase. (982 aa)
BMXTyrosine-protein kinase. (655 aa)
FYNTyrosine-protein kinase. (537 aa)
PTK6Tyrosine-protein kinase. (450 aa)
SRMSTyrosine-protein kinase. (534 aa)
RRADGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (308 aa)
SASH3SAM and SH3 domain containing 3. (380 aa)
SH3GL1SH3 domain containing GRB2 like 1, endophilin A2. (368 aa)
KHDRBS3KH RNA binding domain containing, signal transduction associated 3. (346 aa)
SVEP1Sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1. (3492 aa)
ITKTyrosine-protein kinase. (620 aa)
LOC101962660Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (544 aa)
LRIT1Leucine rich repeat, Ig-like and transmembrane domains 1. (623 aa)
VAV1Vav guanine nucleotide exchange factor 1. (822 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
ZAP70Tyrosine-protein kinase. (608 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1213 aa)
CD8ACD8a molecule. (238 aa)
KHDRBS2KH RNA binding domain containing, signal transduction associated 2. (349 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
MATKTyrosine-protein kinase. (466 aa)
CBLBCbl proto-oncogene B. (985 aa)
LCKTyrosine-protein kinase. (521 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
BLNKB cell linker. (456 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (346 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
KHDRBS1KH RNA binding domain containing, signal transduction associated 1. (443 aa)
PTK7Protein tyrosine kinase 7 (inactive); Belongs to the protein kinase superfamily. Tyr protein kinase family. (1063 aa)
RASGRF1Ras protein specific guanine nucleotide releasing factor 1. (1269 aa)
PTPN22Protein tyrosine phosphatase non-receptor type 22. (754 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (427 aa)
PAG1Phosphoprotein membrane anchor with glycosphingolipid microdomains 1. (430 aa)
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)
LCP2Lymphocyte cytosolic protein 2. (533 aa)
LOC101965906Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa)
LRIT3Leucine rich repeat, Ig-like and transmembrane domains 3. (623 aa)
MOSMOS proto-oncogene, serine/threonine kinase; Belongs to the protein kinase superfamily. (349 aa)
FGRTyrosine-protein kinase. (527 aa)
TXKTyrosine-protein kinase. (526 aa)
CD3DCD3d molecule. (170 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
DNAAF2Protein kintoun; Required for cytoplasmic pre-assembly of axonemal dyneins, thereby playing a central role in motility in cilia and flagella. Involved in pre-assembly of dynein arm complexes in the cytoplasm before intraflagellar transport loads them for the ciliary compartment. (920 aa)
CLNKCytokine dependent hematopoietic cell linker. (423 aa)
IRS1Insulin receptor substrate 1. (1241 aa)
StimateUncharacterized protein. (316 aa)
Col22a1VWFA domain-containing protein. (1607 aa)
HGFACHGF activator. (653 aa)
METMET proto-oncogene, receptor tyrosine kinase. (1380 aa)
LRIG1Leucine rich repeats and immunoglobulin like domains 1. (1075 aa)
RRAS2RAS related 2. (173 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
CD247CD247 molecule. (144 aa)
Fcgr2bUncharacterized protein. (341 aa)
CSKTyrosine-protein kinase. (450 aa)
Mustn1Uncharacterized protein. (82 aa)
I3N7U1_ICTTRUncharacterized protein. (295 aa)
PTPN12Tyrosine-protein phosphatase non-receptor type 12; Dephosphorylates a range of proteins, and thereby regulates cellular signaling cascades. (778 aa)
GRAPUncharacterized protein. (157 aa)
GAS6Growth arrest specific 6. (654 aa)
DOK2Docking protein 2. (404 aa)
SAMSN1SAM domain, SH3 domain and nuclear localization signals 1. (373 aa)
STAP2Signal transducing adaptor family member 2. (409 aa)
CD4CD4 molecule. (451 aa)
SH3KBP1SH3 domain containing kinase binding protein 1. (690 aa)
LOC101968118Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa)
RIPK4Receptor interacting serine/threonine kinase 4. (803 aa)
ENSSTOP00000025526Uncharacterized protein. (64 aa)
LATLinker for activation of T cells. (234 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1180 aa)
TECTyrosine-protein kinase. (630 aa)
AXLAXL receptor tyrosine kinase. (887 aa)
Pik3r3Uncharacterized protein. (461 aa)
LYNTyrosine-protein kinase. (512 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
PTPN6Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1334 aa)
Shc2Uncharacterized protein. (581 aa)
P3R3URFPIK3R3 upstream reading frame. (91 aa)
VAV3Vav guanine nucleotide exchange factor 3. (847 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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