(5 nodes) Tyrosine-protein kinase, insulin-like receptor, and Insulin family network (Ictidomys tridecemlineatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	INSR	Tyrosine-protein kinase receptor. (1359 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1368 aa)
	Ins	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (110 aa)
	INSRR	Tyrosine-protein kinase receptor. (1279 aa)
	IGF1	Insulin like growth factor 1. (166 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
IGF1	IGF1R	ENSSTOP00000029785	ENSSTOP00000010241	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.997
IGF1	INSR	ENSSTOP00000029785	ENSSTOP00000000977	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.995
IGF1	INSRR	ENSSTOP00000029785	ENSSTOP00000018697	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.973
IGF1	Ins	ENSSTOP00000029785	ENSSTOP00000017025	Insulin like growth factor 1.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.956
IGF1R	IGF1	ENSSTOP00000010241	ENSSTOP00000029785	Tyrosine-protein kinase receptor.	Insulin like growth factor 1.	0.997
IGF1R	INSR	ENSSTOP00000010241	ENSSTOP00000000977	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.991
IGF1R	INSRR	ENSSTOP00000010241	ENSSTOP00000018697	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.956
IGF1R	Ins	ENSSTOP00000010241	ENSSTOP00000017025	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.987
INSR	IGF1	ENSSTOP00000000977	ENSSTOP00000029785	Tyrosine-protein kinase receptor.	Insulin like growth factor 1.	0.995
INSR	IGF1R	ENSSTOP00000000977	ENSSTOP00000010241	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.991
INSR	INSRR	ENSSTOP00000000977	ENSSTOP00000018697	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.934
INSR	Ins	ENSSTOP00000000977	ENSSTOP00000017025	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.995
INSRR	IGF1	ENSSTOP00000018697	ENSSTOP00000029785	Tyrosine-protein kinase receptor.	Insulin like growth factor 1.	0.973
INSRR	IGF1R	ENSSTOP00000018697	ENSSTOP00000010241	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.956
INSRR	INSR	ENSSTOP00000018697	ENSSTOP00000000977	Tyrosine-protein kinase receptor.	Tyrosine-protein kinase receptor.	0.934
INSRR	Ins	ENSSTOP00000018697	ENSSTOP00000017025	Tyrosine-protein kinase receptor.	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.973
Ins	IGF1	ENSSTOP00000017025	ENSSTOP00000029785	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin like growth factor 1.	0.956
Ins	IGF1R	ENSSTOP00000017025	ENSSTOP00000010241	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.987
Ins	INSR	ENSSTOP00000017025	ENSSTOP00000000977	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.995
Ins	INSRR	ENSSTOP00000017025	ENSSTOP00000018697	Insulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.973