(10 nodes) Positive regulation of transcription of Notch receptor target, and Notch, C-terminal network (Ictidomys tridecemlineatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	NOTCH3	Notch receptor 3. (2277 aa)
	MAML3	Mastermind like transcriptional coactivator 3. (1013 aa)
	NOTCH2	Notch receptor 2. (2364 aa)
	NOTCH1	Notch receptor 1. (2466 aa)
	RBPJL	Recombination signal binding protein for immunoglobulin kappa J region like. (542 aa)
	MAML1	Mastermind like transcriptional coactivator 1. (1024 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1106 aa)
	RBPJ	Recombination signal binding protein for immunoglobulin kappa J region. (522 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
	LOC101959658	Uncharacterized protein. (415 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
JAG1	JAG2	ENSSTOP00000026569	ENSSTOP00000017412	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.910
JAG1	LOC101959658	ENSSTOP00000026569	ENSSTOP00000031202	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.716
JAG1	MAML1	ENSSTOP00000026569	ENSSTOP00000012228	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 1.	0.743
JAG1	MAML3	ENSSTOP00000026569	ENSSTOP00000004000	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 3.	0.705
JAG1	NOTCH1	ENSSTOP00000026569	ENSSTOP00000005319	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1.	0.995
JAG1	NOTCH2	ENSSTOP00000026569	ENSSTOP00000004190	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.970
JAG1	NOTCH3	ENSSTOP00000026569	ENSSTOP00000003054	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 3.	0.956
JAG1	RBPJ	ENSSTOP00000026569	ENSSTOP00000025917	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region.	0.805
JAG1	RBPJL	ENSSTOP00000026569	ENSSTOP00000008339	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region like.	0.641
JAG2	JAG1	ENSSTOP00000017412	ENSSTOP00000026569	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.910
JAG2	LOC101959658	ENSSTOP00000017412	ENSSTOP00000031202	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.698
JAG2	MAML1	ENSSTOP00000017412	ENSSTOP00000012228	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 1.	0.686
JAG2	MAML3	ENSSTOP00000017412	ENSSTOP00000004000	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Mastermind like transcriptional coactivator 3.	0.685
JAG2	NOTCH1	ENSSTOP00000017412	ENSSTOP00000005319	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1.	0.992
JAG2	NOTCH2	ENSSTOP00000017412	ENSSTOP00000004190	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.958
JAG2	NOTCH3	ENSSTOP00000017412	ENSSTOP00000003054	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 3.	0.958
JAG2	RBPJ	ENSSTOP00000017412	ENSSTOP00000025917	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region.	0.772
JAG2	RBPJL	ENSSTOP00000017412	ENSSTOP00000008339	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Recombination signal binding protein for immunoglobulin kappa J region like.	0.601
LOC101959658	JAG1	ENSSTOP00000031202	ENSSTOP00000026569	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.716
LOC101959658	JAG2	ENSSTOP00000031202	ENSSTOP00000017412	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.698