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NME8 | NME/NM23 family member 8. (518 aa) | ||||
GPX1 | Glutathione peroxidase; Belongs to the glutathione peroxidase family. (201 aa) | ||||
LCN2 | Lipocalin 2; Belongs to the calycin superfamily. Lipocalin family. (198 aa) | ||||
PRDX1 | Peroxiredoxin 1. (199 aa) | ||||
PRKAA1 | Non-specific serine/threonine protein kinase. (561 aa) | ||||
ENSSTOP00000024247 | Uncharacterized protein. (327 aa) | ||||
Rps3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (244 aa) | ||||
CRK | CRK proto-oncogene, adaptor protein. (305 aa) | ||||
NFE2L2 | Nuclear factor, erythroid 2 like 2. (600 aa) | ||||
RNF112 | Ring finger protein 112. (645 aa) | ||||
MAPK7 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (812 aa) | ||||
EDN1 | Endothelin 1. (202 aa) | ||||
FER | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) | ||||
Glrx2 | Glutaredoxin domain-containing protein. (122 aa) | ||||
MAPK3 | Mitogen-activated protein kinase. (361 aa) | ||||
NUDT15 | Nudix hydrolase 15. (171 aa) | ||||
RIPK1 | Receptor interacting serine/threonine kinase 1. (665 aa) | ||||
CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) | ||||
RIPK3 | Receptor interacting serine/threonine kinase 3; Belongs to the protein kinase superfamily. (491 aa) | ||||
PRDX3 | Peroxiredoxin 3. (257 aa) | ||||
ATP7A | ATPase copper transporting alpha. (1495 aa) | ||||
FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) | ||||
PPIF | Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (207 aa) | ||||
TRPC6 | Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (903 aa) | ||||
UCP1 | Uncoupling protein 1; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1521 aa) | ||||
FOSL1 | FOS like 1, AP-1 transcription factor subunit. (275 aa) | ||||
ZNF277 | Zinc finger protein 277. (458 aa) | ||||
PDGFD | Platelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (370 aa) | ||||
SOD1 | Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (152 aa) | ||||
KPNA4 | Karyopherin subunit alpha 4. (601 aa) | ||||
PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa) | ||||
FABP1 | Fatty acid binding protein 1. (127 aa) | ||||
NR4A3 | Nuclear receptor subfamily 4 group A member 3. (630 aa) | ||||
BTK | Tyrosine-protein kinase. (659 aa) | ||||
I3M4W8_ICTTR | Uncharacterized protein. (207 aa) | ||||
Hif1a | Uncharacterized protein. (821 aa) | ||||
UCP3 | Uncoupling protein 3; Belongs to the mitochondrial carrier (TC 2.A.29) family. (308 aa) | ||||
TRPA1 | Transient receptor potential cation channel subfamily A member 1. (1044 aa) | ||||
NOX1 | NADPH oxidase 1. (561 aa) | ||||
APTX | Aprataxin. (334 aa) | ||||
MB | Myoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (154 aa) | ||||
MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (121 aa) | ||||
LOC101973389 | Uncharacterized protein. (182 aa) | ||||
MMP9 | Matrix metallopeptidase 9. (667 aa) | ||||
PLK3 | Serine/threonine-protein kinase PLK. (646 aa) | ||||
NCF1 | Neutrophil cytosolic factor 1. (405 aa) | ||||
SLC4A1 | Anion exchange protein. (917 aa) | ||||
STK24 | Serine/threonine kinase 24. (432 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1192 aa) | ||||
FYN | Tyrosine-protein kinase. (537 aa) | ||||
NET1 | Neuroepithelial cell transforming 1. (595 aa) | ||||
TNFAIP3 | TNF alpha induced protein 3. (776 aa) | ||||
AIFM1 | Apoptosis inducing factor mitochondria associated 1. (613 aa) | ||||
BAD | BCL2 associated agonist of cell death. (208 aa) | ||||
CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) | ||||
AREG | Amphiregulin. (252 aa) | ||||
Sod2 | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (222 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1307 aa) | ||||
ERN1 | Endoplasmic reticulum to nucleus signaling 1. (972 aa) | ||||
CAPN2 | Calpain 2; Belongs to the peptidase C2 family. (700 aa) | ||||
CCS | Copper chaperone for superoxide dismutase. (274 aa) | ||||
FANCC | Fanconi anemia group C protein homolog; DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Upon IFNG induction, may facilitate STAT1 activation by recruiting STAT1 to IFNGR1. (578 aa) | ||||
STK26 | Serine/threonine kinase 26. (416 aa) | ||||
UBE3A | Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (874 aa) | ||||
ENSSTOP00000030879 | Uncharacterized protein. (105 aa) | ||||
NOS3 | Nitric oxide synthase; Produces nitric oxide (NO). (1228 aa) | ||||
MAPK9 | Mitogen-activated protein kinase. (424 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta. (968 aa) | ||||
ENSSTOP00000030023 | BTB domain-containing protein; Belongs to the potassium channel family. (530 aa) | ||||
MPO | Myeloperoxidase. (718 aa) | ||||
SCGB1A1 | Secretoglobin family 1A member 1. (93 aa) | ||||
CRYAB | Crystallin alpha B; May contribute to the transparency and refractive index of the lens. Has chaperone-like activity, preventing aggregation of various proteins under a wide range of stress conditions. (175 aa) | ||||
APEX1 | DNA-(apurinic or apyrimidinic site) lyase; Initiates repair of AP sites in DNA by catalyzing hydrolytic incision of the phosphodiester backbone immediately adjacent to the damage, generating a single-strand break with 5'-deoxyribose phosphate and 3'-hydroxyl ends. (318 aa) | ||||
Plekha1 | Uncharacterized protein. (343 aa) | ||||
UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) | ||||
Ankzf1 | ANK_REP_REGION domain-containing protein. (541 aa) | ||||
PDGFRA | Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1089 aa) | ||||
TXNRD2 | Thioredoxin reductase 2. (522 aa) | ||||
PAX2 | Paired box 2. (417 aa) | ||||
PTPRK | Protein tyrosine phosphatase receptor type K. (1392 aa) | ||||
BNIP3 | BCL2 interacting protein 3. (217 aa) | ||||
MAPK8 | Mitogen-activated protein kinase. (427 aa) | ||||
HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) | ||||
STAT6 | Signal transducer and activator of transcription. (847 aa) | ||||
SMPD3 | Sphingomyelin phosphodiesterase 3. (655 aa) | ||||
TXNIP | Thioredoxin interacting protein. (391 aa) | ||||
HDAC6 | Histone deacetylase 6. (1142 aa) | ||||
PCGF2 | Polycomb group ring finger 2. (344 aa) | ||||
Rhob | Uncharacterized protein. (196 aa) | ||||
MAPK1 | Mitogen-activated protein kinase. (331 aa) | ||||
PLD2 | Phospholipase. (933 aa) | ||||
ROMO1 | Reactive oxygen species modulator 1. (79 aa) | ||||
Aqp1 | Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa) | ||||
OSER1 | Oxidative stress responsive serine rich 1. (292 aa) | ||||
PARP1 | Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1014 aa) | ||||
NQO1 | NAD(P)H quinone dehydrogenase 1. (275 aa) | ||||
HYAL1 | Hyaluronidase. (449 aa) | ||||
CHUK | Component of inhibitor of nuclear factor kappa B kinase complex. (769 aa) | ||||
ZNF580 | Zinc finger protein 580. (172 aa) | ||||
SIRT1 | Sirtuin 1. (602 aa) | ||||
IMPACT | Impact RWD domain protein. (297 aa) | ||||
PPARGC1B | PPARG coactivator 1 beta. (1033 aa) | ||||
ADPRHL2 | ADP-ribosylhydrolase like 2. (389 aa) | ||||
Cfl1 | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (203 aa) | ||||
EZH2 | Enhancer of zeste 2 polycomb repressive complex 2 subunit. (757 aa) | ||||
BAK1 | BCL2 antagonist/killer 1. (208 aa) | ||||
CAPN1 | Calpain 1; Belongs to the peptidase C2 family. (743 aa) | ||||
AGAP3 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (843 aa) | ||||
AXL | AXL receptor tyrosine kinase. (887 aa) | ||||
FKBP1B | Peptidylprolyl isomerase. (108 aa) | ||||
ENSSTOP00000028944 | Uncharacterized protein. (169 aa) | ||||
AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) | ||||
PDK2 | Protein-serine/threonine kinase. (407 aa) | ||||
CDK1 | Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (297 aa) | ||||
MT-ND5 | NADH-ubiquinone oxidoreductase chain 5; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (605 aa) | ||||
SIGMAR1 | Sigma non-opioid intracellular receptor 1. (223 aa) | ||||
MPV17 | Mitochondrial inner membrane protein MPV17; Belongs to the peroxisomal membrane protein PXMP2/4 family. (176 aa) | ||||
MT-ND6 | NADH-ubiquinone oxidoreductase chain 6; Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. (174 aa) | ||||
ENSSTOP00000027321 | Uncharacterized protein. (207 aa) | ||||
HYAL2 | Hyaluronidase. (472 aa) | ||||
ENSSTOP00000027050 | Thioredoxin domain-containing protein. (188 aa) | ||||
HSF1 | Heat shock transcription factor 1. (545 aa) | ||||
HMOX1 | Heme oxygenase 1. (288 aa) | ||||
LIG1 | DNA ligase. (922 aa) | ||||
ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (726 aa) | ||||
I3MU87_ICTTR | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (250 aa) | ||||
STK25 | Serine/threonine kinase 25. (421 aa) | ||||
BCL2 | BCL2 apoptosis regulator. (195 aa) | ||||
I3MVL6_ICTTR | Uncharacterized protein. (192 aa) | ||||
Ect2 | Uncharacterized protein. (188 aa) | ||||
MMP2 | Matrix metallopeptidase 2. (662 aa) | ||||
PJVK | Pejvakin. (348 aa) | ||||
TRPM2 | Transient receptor potential cation channel subfamily M member 2. (1499 aa) | ||||
RELA | RELA proto-oncogene, NF-kB subunit. (551 aa) | ||||
CASP6 | Caspase 6; Belongs to the peptidase C14A family. (268 aa) | ||||
COA8 | Cytochrome c oxidase assembly factor 8. (170 aa) | ||||
I3N090_ICTTR | Uncharacterized protein. (207 aa) | ||||
COL1A1 | Collagen type I alpha 1 chain. (1268 aa) | ||||
ENSSTOP00000025283 | Uncharacterized protein; Belongs to the potassium channel family. (501 aa) | ||||
Becn1 | Beclin 1. (448 aa) | ||||
ALDH3A2 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa) | ||||
LOC101960206 | Uncharacterized protein. (207 aa) | ||||
TREX1 | Three prime repair exonuclease 1. (304 aa) | ||||
SETX | Senataxin. (2708 aa) | ||||
I3N6Q6_ICTTR | ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (160 aa) | ||||
Pdcd10 | Programmed cell death 10. (212 aa) | ||||
I3N7W8_ICTTR | Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (202 aa) | ||||
LOC101956215 | Uncharacterized protein. (195 aa) | ||||
I3N9L4_ICTTR | Protein kinase domain-containing protein. (388 aa) | ||||
ANXA1 | Annexin. (346 aa) | ||||
ADAM9 | ADAM metallopeptidase domain 9. (782 aa) | ||||
CAPN14 | Calpain 14; Belongs to the peptidase C2 family. (674 aa) | ||||
APOD | Apolipoprotein D. (193 aa) | ||||
SPHK1 | Sphingosine kinase 1. (385 aa) | ||||
JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) | ||||
Prdx2 | Thioredoxin domain-containing protein. (198 aa) | ||||
KDM6B | Lysine demethylase 6B. (1651 aa) | ||||
PPP1R15B | Protein phosphatase 1 regulatory subunit 15B. (713 aa) | ||||
Pcna | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) | ||||
PARK7 | Parkinsonism associated deglycase. (189 aa) | ||||
MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa) | ||||
PDGFRB | Platelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1112 aa) | ||||
DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1904 aa) | ||||
MAPK13 | Mitogen-activated protein kinase. (326 aa) |