43 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ABL1	Tyrosine-protein kinase. (1149 aa)
	SAMSN1	SAM domain, SH3 domain and nuclear localization signals 1. (373 aa)
	VAV2	Vav guanine nucleotide exchange factor 2. (745 aa)
	LDLRAP1	Low density lipoprotein receptor adaptor protein 1. (308 aa)
	Shb	SH2 domain-containing protein. (495 aa)
	GRAP	Uncharacterized protein. (157 aa)
	SH3BP2	SH3 domain binding protein 2. (606 aa)
	PTPN6	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (597 aa)
	Pik3r3	Uncharacterized protein. (461 aa)
	SHD	Src homology 2 domain containing transforming protein D. (341 aa)
	SHF	Src homology 2 domain containing F. (321 aa)
	PIK3R1	Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
	CRK	CRK proto-oncogene, adaptor protein. (305 aa)
	STAP1	Signal transducing adaptor family member 1. (297 aa)
	PTPN3	Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (882 aa)
	SHC1	SHC adaptor protein 1. (583 aa)
	I3LWF9_ICTTR	SH2 domain-containing protein. (118 aa)
	RASA1	RAS p21 protein activator 1. (1030 aa)
	MAPK3	Mitogen-activated protein kinase. (361 aa)
	NCK2	Cytoplasmic protein. (380 aa)
	PTPN5	Protein tyrosine phosphatase non-receptor type 5. (538 aa)
	Pik3r2	Uncharacterized protein. (724 aa)
	GRAP2	GRB2 related adaptor protein 2. (324 aa)
	HCK	Tyrosine-protein kinase. (502 aa)
	CBL	Cbl proto-oncogene. (870 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	ACP2	Acid phosphatase 2, lysosomal; Belongs to the histidine acid phosphatase family. (422 aa)
	CRKL	CRK like proto-oncogene, adaptor protein. (303 aa)
	SH2D3C	SH2 domain containing 3C. (858 aa)
	SHE	Src homology 2 domain containing E. (430 aa)
	VAV1	Vav guanine nucleotide exchange factor 1. (822 aa)
	SOCS3	Suppressor of cytokine signaling 3. (227 aa)
	ZAP70	Tyrosine-protein kinase. (608 aa)
	CBLB	Cbl proto-oncogene B. (985 aa)
	LCK	Tyrosine-protein kinase. (521 aa)
	GRB2	Growth factor receptor bound protein 2. (217 aa)
	Bcar3	Uncharacterized protein. (186 aa)
	MAPK1	Mitogen-activated protein kinase. (331 aa)
	FGR	Tyrosine-protein kinase. (527 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	PFN1	Profilin; Belongs to the profilin family. (140 aa)
	ABL2	Tyrosine-protein kinase. (1142 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABL1	CBL	ENSSTOP00000023658	ENSSTOP00000004776	Tyrosine-protein kinase.	Cbl proto-oncogene.	0.920
ABL1	CBLB	ENSSTOP00000023658	ENSSTOP00000010809	Tyrosine-protein kinase.	Cbl proto-oncogene B.	0.869
ABL1	CRK	ENSSTOP00000023658	ENSSTOP00000024503	Tyrosine-protein kinase.	CRK proto-oncogene, adaptor protein.	0.978
ABL1	CRKL	ENSSTOP00000023658	ENSSTOP00000007779	Tyrosine-protein kinase.	CRK like proto-oncogene, adaptor protein.	0.952
ABL1	FGR	ENSSTOP00000023658	ENSSTOP00000015995	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.407
ABL1	GRAP	ENSSTOP00000023658	ENSSTOP00000021222	Tyrosine-protein kinase.	Uncharacterized protein.	0.764
ABL1	GRAP2	ENSSTOP00000023658	ENSSTOP00000001984	Tyrosine-protein kinase.	GRB2 related adaptor protein 2.	0.764
ABL1	GRB2	ENSSTOP00000023658	ENSSTOP00000011345	Tyrosine-protein kinase.	Growth factor receptor bound protein 2.	0.943
ABL1	I3LWF9_ICTTR	ENSSTOP00000023658	ENSSTOP00000000314	Tyrosine-protein kinase.	SH2 domain-containing protein.	0.859
ABL1	MAPK1	ENSSTOP00000023658	ENSSTOP00000013254	Tyrosine-protein kinase.	Mitogen-activated protein kinase.	0.605
ABL1	MAPK3	ENSSTOP00000023658	ENSSTOP00000000787	Tyrosine-protein kinase.	Mitogen-activated protein kinase.	0.605
ABL1	NCK2	ENSSTOP00000023658	ENSSTOP00000000828	Tyrosine-protein kinase.	Cytoplasmic protein.	0.499
ABL1	PIK3R1	ENSSTOP00000023658	ENSSTOP00000026032	Tyrosine-protein kinase.	Phosphoinositide-3-kinase regulatory subunit 1.	0.463
ABL1	Pik3r2	ENSSTOP00000023658	ENSSTOP00000001718	Tyrosine-protein kinase.	Uncharacterized protein.	0.434
ABL1	Pik3r3	ENSSTOP00000023658	ENSSTOP00000029236	Tyrosine-protein kinase.	Uncharacterized protein.	0.434
ABL1	SHC1	ENSSTOP00000023658	ENSSTOP00000000045	Tyrosine-protein kinase.	SHC adaptor protein 1.	0.861
ABL1	SOCS3	ENSSTOP00000023658	ENSSTOP00000009768	Tyrosine-protein kinase.	Suppressor of cytokine signaling 3.	0.443
ABL1	VAV1	ENSSTOP00000023658	ENSSTOP00000009699	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 1.	0.433
ABL1	VAV2	ENSSTOP00000023658	ENSSTOP00000022046	Tyrosine-protein kinase.	Vav guanine nucleotide exchange factor 2.	0.433
ABL2	CBL	ENSSTOP00000020777	ENSSTOP00000004776	Tyrosine-protein kinase.	Cbl proto-oncogene.	0.920