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| | CYP2R1 | Cytochrome P450 family 2 subfamily R member 1. (453 aa) |
| | MYOF | Myoferlin. (1917 aa) |
| | INPP5A | Inositol polyphosphate-5-phosphatase A. (387 aa) |
| | THTPA | Thiamine-triphosphatase; Hydrolase highly specific for thiamine triphosphate (ThTP). (224 aa) |
| | IDH1 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (413 aa) |
| | NFE2L1 | Nuclear factor, erythroid 2 like 1. (771 aa) |
| | SCNN1B | Sodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa) |
| | DHRS3 | Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa) |
| | CBR4 | Carbonyl reductase 4. (237 aa) |
| | PLA2G4A | Phospholipase A2. (750 aa) |
| | LIPC | Lipase C, hepatic type. (463 aa) |
| | LOC101978171 | Aldo_ket_red domain-containing protein. (322 aa) |
| | PLCB3 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa) |
| | PIP4P1 | Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (277 aa) |
| | MTMR2 | Myotubularin related protein 2. (643 aa) |
| | CYP39A1 | Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (473 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1152 aa) |
| | DYSF | Dysferlin. (2121 aa) |
| | PCBD1 | Pterin-4 alpha-carbinolamine dehydratase 1. (103 aa) |
| | IP6K2 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (448 aa) |
| | BPNT1 | 3'(2'), 5'-bisphosphate nucleotidase 1. (323 aa) |
| | ACO2 | Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (780 aa) |
| | Rdh11 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa) |
| | QDPR | Quinoid dihydropteridine reductase. (242 aa) |
| | CUBN | Cubilin. (3522 aa) |
| | DHDDS | Alkyl transferase; Belongs to the UPP synthase family. (333 aa) |
| | LOC101968888 | Uncharacterized protein. (204 aa) |
| | FGFR1 | Fibroblast growth factor receptor. (822 aa) |
| | APP | Amyloid beta precursor protein. (739 aa) |
| | TKFC | Triokinase and FMN cyclase. (578 aa) |
| | MECP2 | Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (486 aa) |
| | ENSSTOP00000026005 | Uncharacterized protein. (55 aa) |
| | PNPLA2 | Patatin like phospholipase domain containing 2. (489 aa) |
| | INPP4B | Inositol polyphosphate-4-phosphatase type II B. (939 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (254 aa) |
| | MSMO1 | Methylsterol monooxygenase 1; Belongs to the sterol desaturase family. (292 aa) |
| | PLPP1 | Phospholipid phosphatase 1. (285 aa) |
| | Gk | Uncharacterized protein; Belongs to the FGGY kinase family. (559 aa) |
| | ALDH3A2 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa) |
| | ABHD4 | Abhydrolase domain containing 4. (355 aa) |
| | PSORS1C2 | Psoriasis susceptibility 1 candidate 2. (134 aa) |
| | ENSSTOP00000024546 | GTP_cyclohydroI domain-containing protein. (221 aa) |
| | ADH4 | Alcohol dehydrogenase 4 (class II), pi polypeptide. (298 aa) |
| | SCAP | SREBF chaperone. (1322 aa) |
| | ENSSTOP00000024049 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (243 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (561 aa) |
| | LOC106145384 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (495 aa) |
| | DGAT1 | O-acyltransferase. (500 aa) |
| | Nudt4 | Nudix hydrolase domain-containing protein. (147 aa) |
| | HSD17B7 | Hydroxysteroid 17-beta dehydrogenase 7. (335 aa) |
| | I3NFV0_ICTTR | Uncharacterized protein. (216 aa) |
| | I3NFT9_ICTTR | COesterase domain-containing protein. (179 aa) |
| | Gch1 | GTP_cyclohydroI domain-containing protein. (241 aa) |
| | DBH | Dopamine beta-hydroxylase. (620 aa) |
| | ITPKC | Kinase; Belongs to the inositol phosphokinase (IPK) family. (667 aa) |
| | LOC101967418 | Uncharacterized protein. (2364 aa) |
| | PPIP5K2 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1244 aa) |
| | ABCA5 | ATP binding cassette subfamily A member 5. (1642 aa) |
| | MT3 | Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa) |
| | PARK7 | Parkinsonism associated deglycase. (189 aa) |
| | ITPKB | Kinase; Belongs to the inositol phosphokinase (IPK) family. (951 aa) |
| | Plpp3 | acidPPc domain-containing protein. (312 aa) |
| | LOC101973436 | Aldo_ket_red domain-containing protein. (310 aa) |
| | SPHK1 | Sphingosine kinase 1. (385 aa) |
| | NAPEPLD | N-acyl phosphatidylethanolamine phospholipase D. (400 aa) |
| | LDLRAP1 | Low density lipoprotein receptor adaptor protein 1. (308 aa) |
| | Shpk | FGGY_N domain-containing protein. (476 aa) |
| | CYP1A2 | Cytochrome P450 family 1 subfamily A member 2; Belongs to the cytochrome P450 family. (515 aa) |
| | MIOX | Myo-inositol oxygenase. (285 aa) |
| | APOA2 | Apolipoprotein A2. (101 aa) |
| | TPI1 | Triosephosphate isomerase. (299 aa) |
| | ERLIN2 | ER lipid raft associated 2. (339 aa) |
| | I3N8J7_ICTTR | Uncharacterized protein. (191 aa) |
| | APOB | Apolipoprotein B. (4482 aa) |
| | CEL | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (558 aa) |
| | G6PD | Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa) |
| | SPTSSB | Serine palmitoyltransferase small subunit B. (76 aa) |
| | NSDHL | NAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (361 aa) |
| | MOGAT3 | Monoacylglycerol O-acyltransferase 3. (343 aa) |
| | Cln8 | CLN8 transmembrane ER and ERGIC protein. (288 aa) |
| | CYB5R3 | NADH-cytochrome b5 reductase; Belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (294 aa) |
| | ACPP | Acid phosphatase, prostate; Belongs to the histidine acid phosphatase family. (418 aa) |
| | ALDH16A1 | Aldehyde dehydrogenase family 16 member A1. (832 aa) |
| | LEPR | Leptin receptor. (1148 aa) |
| | LOC101964273 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | TSKU | Tsukushi, small leucine rich proteoglycan. (357 aa) |
| | I3N5A9_ICTTR | Uncharacterized protein. (204 aa) |
| | TKTL2 | Transketolase like 2. (627 aa) |
| | SPTSSA | Serine palmitoyltransferase small subunit A. (71 aa) |
| | LOC101970547 | Nudix hydrolase domain-containing protein. (227 aa) |
| | I3N458_ICTTR | Uncharacterized protein. (369 aa) |
| | ACER2 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa) |
| | SCARB1 | Scavenger receptor class B member 1; Belongs to the CD36 family. (430 aa) |
| | ISYNA1 | Inositol-3-phosphate synthase 1. (555 aa) |
| | TPK1 | Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (243 aa) |
| | IP6K3 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (404 aa) |
| | LOC101967023 | IPPc domain-containing protein. (573 aa) |
| | SDR9C7 | Short chain dehydrogenase/reductase family 9C member 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (313 aa) |
| | IMPAD1 | Inositol monophosphatase domain containing 1. (329 aa) |
| | Idi1 | Nudix hydrolase domain-containing protein. (263 aa) |
| | Akr1b1 | Aldo_ket_red domain-containing protein. (316 aa) |
| | ALDH1B1 | Aldehyde dehydrogenase 1 family member B1; Belongs to the aldehyde dehydrogenase family. (523 aa) |
| | ITPK1 | Inositol-tetrakisphosphate 1-kinase. (414 aa) |
| | Cebpa | Uncharacterized protein. (122 aa) |
| | APOA5 | Apolipoprotein A5. (370 aa) |
| | I3MYT1_ICTTR | Aldo_ket_red domain-containing protein. (263 aa) |
| | NUDT11 | Nudix hydrolase 11. (164 aa) |
| | SCP2 | Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa) |
| | LOC101976546 | PKS_ER domain-containing protein. (375 aa) |
| | PLPP2 | Phospholipid phosphatase 2. (287 aa) |
| | LOC101964695 | Iso_dh domain-containing protein. (398 aa) |
| | RDH16 | Retinol dehydrogenase 16; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (317 aa) |
| | LOC101963060 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (296 aa) |
| | Slc5a3 | Uncharacterized protein; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family. (151 aa) |
| | ABCG1 | ATP binding cassette subfamily G member 1. (666 aa) |
| | PNPLA4 | Patatin like phospholipase domain containing 4. (253 aa) |
| | NUS1 | NUS1 dehydrodolichyl diphosphate synthase subunit. (278 aa) |
| | PMP22 | Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa) |
| | ASAH2 | Neutral ceramidase. (716 aa) |
| | EPHX1 | Epoxide hydrolase; Biotransformation enzyme that catalyzes the hydrolysis of arene and aliphatic epoxides to less reactive and more water soluble dihydrodiols by the trans addition of water. Belongs to the peptidase S33 family. (454 aa) |
| | Pgp | Uncharacterized protein. (122 aa) |
| | Cacna1h | Uncharacterized protein. (2259 aa) |
| | RETSAT | Retinol saturase. (610 aa) |
| | LOC101956324 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (536 aa) |
| | LCAT | Lecithin-cholesterol acyltransferase. (440 aa) |
| | Fgf2 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (144 aa) |
| | PTEN | Phosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa) |
| | SULT2B1 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (340 aa) |
| | SPTLC3 | Serine palmitoyltransferase long chain base subunit 3. (552 aa) |
| | NPC1L1 | NPC1 like intracellular cholesterol transporter 1. (1331 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | INPP1 | Inositol polyphosphate-1-phosphatase. (399 aa) |
| | LOC101973014 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (402 aa) |
| | SYNJ2 | Synaptojanin 2. (1471 aa) |
| | HSD11B2 | Hydroxysteroid 11-beta dehydrogenase 2. (398 aa) |
| | MVD | Diphosphomevalonate decarboxylase; Performs the first committed step in the biosynthesis of isoprenes. (376 aa) |
| | SRD5A3 | Steroid 5 alpha-reductase 3. (318 aa) |
| | PLCB1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa) |
| | SGPP2 | Sphingosine-1-phosphate phosphatase 2. (399 aa) |
| | OCRL | OCRL inositol polyphosphate-5-phosphatase. (901 aa) |
| | RBP4 | Apolipoprotein D. (163 aa) |
| | PTAFR | Platelet activating factor receptor; Belongs to the G-protein coupled receptor 1 family. (342 aa) |
| | SYNJ1 | Synaptojanin 1. (1609 aa) |
| | RDH12 | Retinol dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (316 aa) |
| | ASAH1 | N-acylsphingosine amidohydrolase 1; Belongs to the acid ceramidase family. (395 aa) |
| | CLN6 | CLN6 transmembrane ER protein. (312 aa) |
| | Spr | Uncharacterized protein. (267 aa) |
| | IPPK | Inositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (489 aa) |
| | ALDH3B1 | Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (468 aa) |
| | Rdh8 | Uncharacterized protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (311 aa) |
| | Aldh2 | Aldedh domain-containing protein; Belongs to the aldehyde dehydrogenase family. (545 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | Dpm1 | Dolichol-phosphate mannosyltransferase subunit 1; Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O-mannosylation of proteins. (260 aa) |
| | AKR1E2 | Aldo-keto reductase family 1 member E2. (301 aa) |
| | DPAGT1 | Dolichyl-phosphate N-acetylglucosaminephosphotransferase 1. (408 aa) |
| | Inpp5e | IPPc domain-containing protein. (438 aa) |
| | CYP1A1 | Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (523 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase. (303 aa) |
| | ABCA2 | ATP binding cassette subfamily A member 2. (2414 aa) |
| | IP6K1 | Kinase; Belongs to the inositol phosphokinase (IPK) family. (433 aa) |
| | GK5 | Glycerol kinase 5; Belongs to the FGGY kinase family. (511 aa) |
| | AKR1A1 | Aldo-keto reductase family 1 member A1. (325 aa) |
| | LRP1 | LDL receptor related protein 1. (4508 aa) |
| | HDLBP | High density lipoprotein binding protein. (1265 aa) |
| | GALK1 | Galactokinase 1. (392 aa) |
| | PTS | 6-pyruvoyl tetrahydrobiopterin synthase. (117 aa) |
| | CH25H | Cholesterol 25-hydroxylase; Belongs to the sterol desaturase family. (286 aa) |
| | Srebf2 | BHLH domain-containing protein. (1136 aa) |
| | IMPA1 | Inositol-1-monophosphatase. (277 aa) |
| | IDH3B | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (383 aa) |
| | SPTLC1 | Serine palmitoyltransferase long chain base subunit 1. (473 aa) |
| | IMPA2 | Inositol-1-monophosphatase. (288 aa) |
| | LRP5 | Uncharacterized protein. (1516 aa) |
| | SPHK2 | Sphingosine kinase 2. (655 aa) |
| | SOAT1 | O-acyltransferase. (544 aa) |
| | DGAT2 | Diacylglycerol O-acyltransferase 2. (388 aa) |
| | PON1 | Paraoxonase 1. (355 aa) |
| | PLCG1 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa) |
| | Lipe | Hormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. (763 aa) |
| | LOC101971868 | Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (566 aa) |
| | CHKA | Choline kinase alpha. (411 aa) |
| | SGPP1 | Sphingosine-1-phosphate phosphatase 1. (428 aa) |
| | SOAT2 | O-acyltransferase. (524 aa) |
| | CDCP2 | CUB domain containing protein 2. (400 aa) |
| | CYP7B1 | Cytochrome P450 family 7 subfamily B member 1; Belongs to the cytochrome P450 family. (497 aa) |
| | INPPL1 | Inositol polyphosphate phosphatase like 1. (1264 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | TMEM130 | Transmembrane protein 130. (338 aa) |
| | MVK | Mevalonate kinase; Catalyzes the phosphorylation of mevalonate to mevalonate 5- phosphate, a key step in isoprenoid and cholesterol biosynthesis. Belongs to the GHMP kinase family. Mevalonate kinase subfamily. (396 aa) |
| | MOXD1 | Monooxygenase DBH like 1. (613 aa) |
| | RDH5 | Retinol dehydrogenase 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | APLP2 | Amyloid beta precursor like protein 2. (760 aa) |
| | IDI2 | Isopentenyl-diphosphate delta isomerase 2. (217 aa) |
| | DHRS9 | Dehydrogenase/reductase 9; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (319 aa) |
| | FDXR | NADPH:adrenodoxin oxidoreductase, mitochondrial. (492 aa) |
| | HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (888 aa) |
| | EDNRB | Endothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa) |
| | MTMR7 | Myotubularin related protein 7. (661 aa) |
| | SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa) |
| | ALDH1A3 | Aldehyde dehydrogenase 1 family member A3; Belongs to the aldehyde dehydrogenase family. (520 aa) |
| | SC5D | Sterol-C5-desaturase; Belongs to the sterol desaturase family. (299 aa) |
| | GBA | Glucosylceramidase. (516 aa) |
| | SORD | Sorbitol dehydrogenase. (357 aa) |
| | GDE1 | Glycerophosphodiester phosphodiesterase 1. (328 aa) |
| | CAT | Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa) |
| | SQLE | Squalene epoxidase. (574 aa) |
| | SLC34A1 | Solute carrier family 34 member 1. (639 aa) |
| | ITPKA | Kinase; Belongs to the inositol phosphokinase (IPK) family. (460 aa) |
| | MBTPS1 | Membrane bound transcription factor peptidase, site 1. (1052 aa) |
| | IDH3G | Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (393 aa) |
| | PCTP | Phosphatidylcholine transfer protein. (213 aa) |
| | LDLR | Low density lipoprotein receptor. (863 aa) |
| | Coq2 | Uncharacterized protein. (123 aa) |
| | GDPD1 | Glycerophosphodiester phosphodiesterase domain containing 1. (314 aa) |
| | PCK2 | Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa) |
| | TTR | Transthyretin; Thyroid hormone-binding protein. Probably transports thyroxine from the bloodstream to the brain. (147 aa) |
| | GOT1 | Aspartate aminotransferase. (413 aa) |
| | LSS | Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family. (733 aa) |
| | BCO1 | Beta-carotene oxygenase 1. (471 aa) |
| | DHRS7 | Dehydrogenase/reductase 7; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (420 aa) |
| | PPIP5K1 | Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1491 aa) |
| | CYP11A1 | Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (519 aa) |
| | VLDLR | Very low density lipoprotein receptor. (873 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (282 aa) |
| | ADH7 | Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (374 aa) |
| | CYP51A1 | Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (503 aa) |
| | CYP27A1 | Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (534 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (504 aa) |
| | ADH5 | S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa) |
| | LBR | Lamin B receptor. (629 aa) |
| | LOC101967457 | DOMON domain-containing protein. (619 aa) |
| | PLCG2 | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa) |
| | I3M6L1_ICTTR | ABC transmembrane type-1 domain-containing protein. (528 aa) |
| | HMGCS1 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (520 aa) |
| | RBP1 | Retinol binding protein 1; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | HSD3B7 | Hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7; Belongs to the 3-beta-HSD family. (369 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (682 aa) |
| | GBA2 | Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (919 aa) |
| | GPD2 | Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (727 aa) |
| | ANGPTL3 | Angiopoietin like 3. (455 aa) |
| | INPP5K | Inositol polyphosphate-5-phosphatase K. (510 aa) |
| | TKTL1 | Transketolase like 1. (596 aa) |
| | LIMA1 | LIM domain and actin binding 1. (603 aa) |
| | HNF1A | HNF1 homeobox A. (449 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | DEGS2 | Delta 4-desaturase, sphingolipid 2. (323 aa) |
| | Fdps | Uncharacterized protein; Belongs to the FPP/GGPP synthase family. (353 aa) |
| | DHCR24 | 24-dehydrocholesterol reductase. (496 aa) |
| | PCBD2 | Pterin-4 alpha-carbinolamine dehydratase 2. (102 aa) |
| | HAO1 | Hydroxyacid oxidase 1. (370 aa) |
| | FDX1 | Ferredoxin 1. (184 aa) |
| | PMVK | Phosphomevalonate kinase. (192 aa) |
| | CETP | Cholesteryl ester transfer protein; Involved in the transfer of neutral lipids, including cholesteryl ester and triglyceride, among lipoprotein particles. Allows the net movement of cholesteryl ester from high density lipoproteins/HDL to triglyceride-rich very low density lipoproteins/VLDL, and the equimolar transport of triglyceride from VLDL to HDL; Belongs to the BPI/LBP/Plunc superfamily. BPI/LBP family. (495 aa) |
| | DHRS13 | Dehydrogenase/reductase 13. (377 aa) |
| | TM7SF2 | Transmembrane 7 superfamily member 2. (418 aa) |
| | ALDH1A1 | Aldehyde dehydrogenase 1 family member A1; Belongs to the aldehyde dehydrogenase family. (501 aa) |
| | SPTLC2 | Serine palmitoyltransferase long chain base subunit 2. (549 aa) |
| | DPM2 | Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family. (84 aa) |
| | SDR16C5 | Short chain dehydrogenase/reductase family 16C member 5; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (309 aa) |
| | IDH2 | Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (452 aa) |
| | ACER3 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (268 aa) |
| | ACER1 | Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (264 aa) |
| | APOA1 | Apolipoprotein A1. (264 aa) |
| | PNLIP | Pancreatic triacylglycerol lipase; Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones (By similarity). Plays a role in hibernation as a key enzyme that shows high activity at low temperatures. When expressed in the hibernating heart it liberates fatty acids from triglycerides at temperatures as low as 0 degrees Celsius. (465 aa) |
| | INPP5J | Inositol polyphosphate-5-phosphatase J. (1002 aa) |
| | FECH | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (423 aa) |
| | HMGCS2 | 3-hydroxy-3-methylglutaryl coenzyme A synthase; This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase. (507 aa) |
| | INPP5B | Inositol polyphosphate-5-phosphatase B. (994 aa) |
| | RPE65 | Retinoid isomerohydrolase RPE65. (533 aa) |
| | CYP1B1 | Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa) |
| | CYP46A1 | Cytochrome P450 family 46 subfamily A member 1; Belongs to the cytochrome P450 family. (500 aa) |
| | IPMK | Kinase; Belongs to the inositol phosphokinase (IPK) family. (416 aa) |
| | AWAT2 | Acyl-CoA wax alcohol acyltransferase 2. (333 aa) |
| | ABCA1 | ATP binding cassette subfamily A member 1. (2261 aa) |
| | CYP27B1 | Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (504 aa) |
| | RDH13 | Retinol dehydrogenase 13; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (340 aa) |
| | GRK3 | G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (619 aa) |
| | Ebp | EXPERA domain-containing protein. (230 aa) |
| | GDPD3 | Glycerophosphodiester phosphodiesterase domain containing 3. (331 aa) |
| | AKR1D1 | Aldo-keto reductase family 1 member D1. (258 aa) |
| | LOC101972700 | Sulfotransferase; Belongs to the sulfotransferase 1 family. (281 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (801 aa) |
| | ALDH1A2 | Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa) |
