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TPI1 TPI1 MOGAT3 MOGAT3 Gk Gk Shpk Shpk MYOF MYOF PLA2G4A PLA2G4A DYSF DYSF TKFC TKFC ANGPTL3 ANGPTL3 GPD2 GPD2 GOT1 GOT1 PCK2 PCK2 Coq2 Coq2 DGAT2 DGAT2 GK5 GK5 PCK1 PCK1 COQ3 COQ3 LEP LEP Pgp Pgp
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TPI1Triosephosphate isomerase. (299 aa)
MOGAT3Monoacylglycerol O-acyltransferase 3. (343 aa)
GkUncharacterized protein; Belongs to the FGGY kinase family. (559 aa)
ShpkFGGY_N domain-containing protein. (476 aa)
MYOFMyoferlin. (1917 aa)
PLA2G4APhospholipase A2. (750 aa)
DYSFDysferlin. (2121 aa)
TKFCTriokinase and FMN cyclase. (578 aa)
ANGPTL3Angiopoietin like 3. (455 aa)
GPD2Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (727 aa)
GOT1Aspartate aminotransferase. (413 aa)
PCK2Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
Coq2Uncharacterized protein. (123 aa)
DGAT2Diacylglycerol O-acyltransferase 2. (388 aa)
GK5Glycerol kinase 5; Belongs to the FGGY kinase family. (511 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
COQ3Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (402 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
PgpUncharacterized protein. (122 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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