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LIG4 | DNA ligase. (911 aa) | ||||
DCLRE1C | DNA cross-link repair 1C. (689 aa) | ||||
POLM | DNA-directed DNA/RNA polymerase mu; Gap-filling polymerase involved in repair of DNA double- strand breaks by non-homologous end joining (NHEJ). Belongs to the DNA polymerase type-X family. (494 aa) | ||||
ERCC1 | ERCC excision repair 1, endonuclease non-catalytic subunit. (298 aa) | ||||
ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1521 aa) | ||||
KDM2A | Lysine demethylase 2A. (1162 aa) | ||||
ERCC8 | ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa) | ||||
MLH1 | MutL homolog 1. (758 aa) | ||||
POLB | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (306 aa) | ||||
LIG3 | DNA ligase. (1013 aa) | ||||
XRCC5 | X-ray repair cross complementing 5. (734 aa) | ||||
TP53BP1 | Tumor protein p53 binding protein 1. (1968 aa) | ||||
IFFO1 | Intermediate filament family orphan 1; Belongs to the intermediate filament family. (564 aa) | ||||
IFFO2 | Intermediate filament family orphan 2; Belongs to the intermediate filament family. (287 aa) | ||||
XRCC6 | X-ray repair cross complementing 6. (609 aa) | ||||
PRKDC | Protein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4130 aa) | ||||
POLQ | DNA polymerase theta. (2588 aa) | ||||
POLL | DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (575 aa) | ||||
DNTT | DNA nucleotidylexotransferase; Template-independent DNA polymerase which catalyzes the random addition of deoxynucleoside 5'-triphosphate to the 3'-end of a DNA initiator. (467 aa) | ||||
ERCC4 | ERCC excision repair 4, endonuclease catalytic subunit. (916 aa) | ||||
I3MLW0_ICTTR | Uncharacterized protein. (78 aa) | ||||
APLF | Aprataxin and PNKP like factor. (519 aa) | ||||
DCLRE1B | DNA cross-link repair 1B. (533 aa) | ||||
PSMD14 | Proteasome 26S subunit, non-ATPase 14. (310 aa) | ||||
SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (936 aa) | ||||
XRCC1 | X-ray repair cross complementing 1. (632 aa) | ||||
HELQ | Helicase, POLQ like. (1017 aa) | ||||
UVRAG | UV radiation resistance associated. (698 aa) | ||||
LOC101962206 | Uncharacterized protein. (302 aa) | ||||
PNKP | Polynucleotide kinase 3'-phosphatase. (520 aa) | ||||
DCLRE1A | DNA cross-link repair 1A. (1044 aa) | ||||
XRCC4 | X-ray repair cross complementing 4. (330 aa) | ||||
ZBTB7A | Zinc finger and BTB domain containing 7A. (414 aa) | ||||
PAXX | PAXX non-homologous end joining factor. (206 aa) | ||||
MRE11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa) | ||||
Pola1 | DNA polymerase. (767 aa) | ||||
LIG1 | DNA ligase. (922 aa) | ||||
HMCES | Abasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (291 aa) | ||||
CYREN | Cell cycle regulator of NHEJ. (173 aa) | ||||
PRPF19 | Pre-mRNA processing factor 19. (512 aa) |