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| | DAGLB | Diacylglycerol lipase beta. (672 aa) |
| | LOC101974086 | AMP-binding domain-containing protein. (178 aa) |
| | SUGCT | Succinyl-CoA:glutarate-CoA transferase. (438 aa) |
| | Olah | Thioesterase domain-containing protein. (189 aa) |
| | LOC101965270 | FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (360 aa) |
| | LIPI | Lipase I. (415 aa) |
| | PECR | Peroxisomal trans-2-enoyl-CoA reductase. (303 aa) |
| | PLA2G4F | Phospholipase A2. (840 aa) |
| | FADS2 | Fatty acid desaturase 2. (444 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa) |
| | EDN2 | Endothelin 2. (148 aa) |
| | ELOVL3 | Elongation of very long chain fatty acids protein 3; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precurs [...] (270 aa) |
| | ARMC7 | Armadillo repeat containing 7. (198 aa) |
| | Elovl5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa) |
| | LIPG | Lipase G, endothelial type. (500 aa) |
| | ABHD3 | Abhydrolase domain containing 3. (338 aa) |
| | TECR | Trans-2,3-enoyl-CoA reductase. (349 aa) |
| | HACD1 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (202 aa) |
| | SCO1 | SCO cytochrome c oxidase assembly protein 1. (305 aa) |
| | CD74 | CD74 molecule. (279 aa) |
| | EDN1 | Endothelin 1. (202 aa) |
| | Brca1 | Uncharacterized protein. (353 aa) |
| | ACSM5 | Acyl-CoA synthetase medium chain family member 5. (579 aa) |
| | HACD3 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (364 aa) |
| | ACACA | Acetyl-CoA carboxylase alpha. (2383 aa) |
| | ALOX15B | Arachidonate 15-lipoxygenase type B. (678 aa) |
| | FADS1 | Fatty acid desaturase 1. (445 aa) |
| | PRXL2B | Peroxiredoxin like 2B. (181 aa) |
| | HSD17B8 | Hydroxysteroid 17-beta dehydrogenase 8. (259 aa) |
| | SPHK1 | Sphingosine kinase 1. (385 aa) |
| | LOC101955374 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (299 aa) |
| | ALOX12B | Arachidonate 12-lipoxygenase, 12R type. (701 aa) |
| | THNSL2 | Threonine synthase like 2. (484 aa) |
| | ELOVL2 | Elongation of very long chain fatty acids protein 2; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA. Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). May participate to the production [...] (295 aa) |
| | LTC4S | Leukotriene C4 synthase. (151 aa) |
| | LOC101957161 | AMP-binding domain-containing protein. (657 aa) |
| | MGLL | Monoglyceride lipase. (311 aa) |
| | ALOX15 | Arachidonate 15-lipoxygenase. (663 aa) |
| | PTGIS | Prostaglandin I2 synthase; Belongs to the cytochrome P450 family. (414 aa) |
| | HTD2 | Hydroxyacyl-thioester dehydratase type 2. (158 aa) |
| | ACSF3 | Acyl-CoA synthetase family member 3. (584 aa) |
| | PLP1 | Proteolipid protein 1. (277 aa) |
| | PLA2G1B | Phospholipase A(2). (117 aa) |
| | LOC101966452 | FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (349 aa) |
| | TBXAS1 | Thromboxane A synthase 1; Belongs to the cytochrome P450 family. (533 aa) |
| | HNF1A | HNF1 homeobox A. (449 aa) |
| | DECR2 | 2,4-dienoyl-CoA reductase 2. (292 aa) |
| | ALOXE3 | Arachidonate lipoxygenase 3. (711 aa) |
| | PTGES | Prostaglandin E synthase. (153 aa) |
| | OXSM | 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial; May play a role in the biosynthesis of lipoic acid as well as longer chain fatty acids required for optimal mitochondrial function. Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family. (456 aa) |
| | ACACB | Acetyl-CoA carboxylase beta. (2328 aa) |
| | ELOVL7 | Elongation of very long chain fatty acids protein 7; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:3(n-3) acyl-CoAs and C18:3(n-6)-CoAs. Also active toward C20:4-, C18:0-, C18:1-, C18:2- and C16:0-CoAs, and weakly toward C20:0-CoA. Little or no activity toward C22:0-, C24:0 [...] (281 aa) |
| | PTGES2 | Prostaglandin E synthase 2. (384 aa) |
| | HSD17B12 | Hydroxysteroid 17-beta dehydrogenase 12; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (312 aa) |
| | ABHD2 | Abhydrolase domain containing 2. (425 aa) |
| | LOC101964310 | FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (354 aa) |
| | ACSS1 | Acetyl-coenzyme A synthetase. (687 aa) |
| | ACLY | ATP-citrate synthase; Catalyzes the cleavage of citrate into oxaloacetate and acetyl-CoA, the latter serving as common substrate for de novo cholesterol and fatty acid synthesis; In the N-terminal section; belongs to the succinate/malate CoA ligase beta subunit family. (1101 aa) |
| | ALOX12 | Arachidonate 12-lipoxygenase, 12S type. (664 aa) |
| | SCD5 | Stearoyl-CoA desaturase 5; Belongs to the fatty acid desaturase type 1 family. (330 aa) |
| | LIPH | Lipase H. (444 aa) |
| | ACSM3 | Acyl-CoA synthetase medium chain family member 3. (580 aa) |
| | MYO5A | Myosin VA; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1845 aa) |
| | I3M9W2_ICTTR | AMP-binding domain-containing protein. (358 aa) |
| | PLA2G10 | Phospholipase A(2). (148 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (739 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | QKI | QKI, KH domain containing RNA binding. (277 aa) |
| | Ptgs2 | EGF-like domain-containing protein. (605 aa) |
| | FADS6 | Fatty acid desaturase 6. (342 aa) |
| | FA2H | Fatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa) |
| | FASN | Fatty acid synthase. (2467 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | LOC101963157 | Uncharacterized protein. (662 aa) |
| | ENSSTOP00000032295 | Uncharacterized protein. (488 aa) |
| | CBR4 | Carbonyl reductase 4. (237 aa) |
| | PLA2G4A | Phospholipase A2. (750 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | HACD4 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (231 aa) |
| | LIPC | Lipase C, hepatic type. (463 aa) |
| | ELOVL1 | Elongation of very long chain fatty acids protein 1; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate to the production of both saturated and monounsaturated VLCFAs of different chain lengths that [...] (279 aa) |
| | ACSBG1 | Acyl-CoA synthetase bubblegum family member 1. (730 aa) |
| | ENSSTOP00000027930 | Uncharacterized protein. (173 aa) |
| | ACSS2 | Acyl-CoA synthetase short chain family member 2. (714 aa) |
| | PNPLA8 | Patatin like phospholipase domain containing 8. (692 aa) |
| | LOC101965950 | FA_desaturase domain-containing protein; Belongs to the fatty acid desaturase type 1 family. (357 aa) |
| | ENSSTOP00000026272 | CS domain-containing protein. (150 aa) |
| | Acsm2b | Uncharacterized protein. (580 aa) |
| | ABCD3 | ATP binding cassette subfamily D member 3. (659 aa) |
| | MCAT | Malonyl-CoA-acyl carrier protein transacylase. (305 aa) |
| | HPGDS | Hematopoietic prostaglandin D synthase; Belongs to the GST superfamily. (204 aa) |
| | PTGES3 | CS domain-containing protein. (182 aa) |
| | ELOVL6 | Elongation of very long chain fatty acids protein 6; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that elongates fatty acids with 12, 14 and 16 carbons with higher activity toward C16:0 acyl-CoAs. Catalyzes the synthesis of unsaturated C16 long chain fatty acids and, to a lesser extent, C18:0 and those with low desaturation degre [...] (265 aa) |
| | ENSSTOP00000024432 | MCD domain-containing protein. (267 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (561 aa) |
| | MECR | Mitochondrial trans-2-enoyl-CoA reductase. (387 aa) |
| | ACOT7 | Acyl-CoA thioesterase 7. (383 aa) |
| | NDUFAB1 | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis. (156 aa) |
| | TMEM196 | Transmembrane protein 196. (148 aa) |
| | THNSL1 | Threonine synthase like 1. (748 aa) |
| | LOC101971249 | Uncharacterized protein. (298 aa) |
| | ASAH2 | Neutral ceramidase. (716 aa) |
| | GSTP1 | Glutathione S-transferase pi 1. (210 aa) |
| | HSDL1 | Hydroxysteroid dehydrogenase like 1; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (330 aa) |
| | TECRL | Trans-2,3-enoyl-CoA reductase like. (363 aa) |
| | HACD2 | Very-long-chain (3R)-3-hydroxyacyl-CoA dehydratase; Catalyzes the third of the four reactions of the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of two carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of fatty acid elongation. Thereby, it participates to the production of VLCFAs of different chain lengths that are involved in multiple biological processes as precursors [...] (254 aa) |
| | ELOVL4 | Elongation of very long chain fatty acids protein 4; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that specifically elongates C24:0 and C26:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane [...] (314 aa) |
| | LOC101973650 | Cytochrome b5 heme-binding domain-containing protein. (483 aa) |
| | FADS3 | Fatty acid desaturase 3. (449 aa) |
| | ACSL3 | Acyl-CoA synthetase long chain family member 3. (720 aa) |
| | ABHD1 | Abhydrolase domain containing 1. (405 aa) |
| | ACSM4 | Acyl-CoA synthetase medium chain family member 4. (580 aa) |
| | LPL | Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (473 aa) |
| | PTGS1 | Prostaglandin-endoperoxide synthase 1. (578 aa) |
| | LIAS | Lipoyl synthase, mitochondrial; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. (375 aa) |
