60 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LIPG	Lipase G, endothelial type. (500 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1500 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (473 aa)
	SLC27A5	Solute carrier family 27 member 5. (690 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (711 aa)
	PCSK9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (682 aa)
	Dbi	ACB domain-containing protein. (87 aa)
	GPAT2	Glycerol-3-phosphate acyltransferase 2, mitochondrial. (801 aa)
	G6PC2	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (640 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (527 aa)
	PNLIPRP2	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (481 aa)
	NKX2-3	NK2 homeobox 3. (360 aa)
	INSIG2	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
	LPIN1	Lipin 1. (930 aa)
	LIPH	Lipase H. (444 aa)
	Lipe	Hormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. (763 aa)
	MOGAT2	Monoacylglycerol O-acyltransferase 2. (334 aa)
	DGAT2	Diacylglycerol O-acyltransferase 2. (388 aa)
	GPAT4	Glycerol-3-phosphate acyltransferase 4. (456 aa)
	CPT1A	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
	CAV3	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (151 aa)
	GK5	Glycerol kinase 5; Belongs to the FGGY kinase family. (511 aa)
	LIPI	Lipase I. (415 aa)
	PNPLA3	Patatin like phospholipase domain containing 3. (420 aa)
	SLC37A4	Solute carrier family 37 member 4. (429 aa)
	PCK1	Phosphoenolpyruvate carboxykinase 1. (622 aa)
	MOGAT1	Monoacylglycerol O-acyltransferase 1. (335 aa)
	SIRT1	Sirtuin 1. (602 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	LMF1	Lipase maturation factor; Involved in the maturation of specific proteins in the endoplasmic reticulum; Belongs to the lipase maturation factor family. (556 aa)
	G6PC	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
	PNPLA4	Patatin like phospholipase domain containing 4. (253 aa)
	APOA5	Apolipoprotein A5. (370 aa)
	LPIN3	Lipin 3. (841 aa)
	Tnxb	Uncharacterized protein. (3000 aa)
	SLC22A4	Solute carrier family 22 member 4. (553 aa)
	GPAT3	Glycerol-3-phosphate acyltransferase 3. (370 aa)
	PNPLA5	Patatin like phospholipase domain containing 5. (389 aa)
	MGLL	Monoglyceride lipase. (311 aa)
	PTPN11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	PLAAT3	Phospholipase A and acyltransferase 3. (189 aa)
	MOGAT3	Monoacylglycerol O-acyltransferase 3. (343 aa)
	APOB	Apolipoprotein B. (4482 aa)
	LPGAT1	Lysophosphatidylglycerol acyltransferase 1. (370 aa)
	APOC3	Apolipoprotein C3. (130 aa)
	Apobr	Uncharacterized protein. (478 aa)
	PNPLA1	Patatin like phospholipase domain containing 1. (515 aa)
	DGAT1	O-acyltransferase. (500 aa)
	APOH	Apolipoprotein H. (306 aa)
	GPX1	Glutathione peroxidase; Belongs to the glutathione peroxidase family. (201 aa)
	SEL1L	SEL1L adaptor subunit of ERAD E3 ubiquitin ligase. (794 aa)
	DDHD2	DDHD domain containing 2. (701 aa)
	LPIN2	Lipin 2. (866 aa)
	Gk	Uncharacterized protein; Belongs to the FGGY kinase family. (559 aa)
	INSIG1	Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (254 aa)
	PNPLA2	Patatin like phospholipase domain containing 2. (489 aa)
	Acsl6	AMP-binding domain-containing protein. (722 aa)
	LIPC	Lipase C, hepatic type. (463 aa)
	GPAM	Glycerol-3-phosphate acyltransferase 1, mitochondrial. (827 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACSL4	Acsl6	ENSSTOP00000004738	ENSSTOP00000029381	Acyl-CoA synthetase long chain family member 4.	AMP-binding domain-containing protein.	0.876
ACSL4	CPT1A	ENSSTOP00000004738	ENSSTOP00000011534	Acyl-CoA synthetase long chain family member 4.	Carnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family.	0.912
ACSL4	DGAT1	ENSSTOP00000004738	ENSSTOP00000023501	Acyl-CoA synthetase long chain family member 4.	O-acyltransferase.	0.414
ACSL4	GPAT3	ENSSTOP00000004738	ENSSTOP00000019611	Acyl-CoA synthetase long chain family member 4.	Glycerol-3-phosphate acyltransferase 3.	0.567
ACSL4	GPAT4	ENSSTOP00000004738	ENSSTOP00000011397	Acyl-CoA synthetase long chain family member 4.	Glycerol-3-phosphate acyltransferase 4.	0.567
ACSL4	LIPC	ENSSTOP00000004738	ENSSTOP00000030828	Acyl-CoA synthetase long chain family member 4.	Lipase C, hepatic type.	0.850
ACSL4	LIPG	ENSSTOP00000004738	ENSSTOP00000014330	Acyl-CoA synthetase long chain family member 4.	Lipase G, endothelial type.	0.859
ACSL4	LPGAT1	ENSSTOP00000004738	ENSSTOP00000021729	Acyl-CoA synthetase long chain family member 4.	Lysophosphatidylglycerol acyltransferase 1.	0.536
ACSL4	LPL	ENSSTOP00000004738	ENSSTOP00000001322	Acyl-CoA synthetase long chain family member 4.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.850
ACSL4	Lipe	ENSSTOP00000004738	ENSSTOP00000010392	Acyl-CoA synthetase long chain family member 4.	Hormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.	0.464
ACSL4	MGLL	ENSSTOP00000004738	ENSSTOP00000019904	Acyl-CoA synthetase long chain family member 4.	Monoglyceride lipase.	0.864
ACSL4	PNLIPRP2	ENSSTOP00000004738	ENSSTOP00000007959	Acyl-CoA synthetase long chain family member 4.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.849
ACSL4	PNPLA2	ENSSTOP00000004738	ENSSTOP00000025960	Acyl-CoA synthetase long chain family member 4.	Patatin like phospholipase domain containing 2.	0.860
ACSL4	PNPLA3	ENSSTOP00000004738	ENSSTOP00000012596	Acyl-CoA synthetase long chain family member 4.	Patatin like phospholipase domain containing 3.	0.853
ACSL4	PNPLA4	ENSSTOP00000004738	ENSSTOP00000016383	Acyl-CoA synthetase long chain family member 4.	Patatin like phospholipase domain containing 4.	0.626
ACSL4	PNPLA5	ENSSTOP00000004738	ENSSTOP00000019753	Acyl-CoA synthetase long chain family member 4.	Patatin like phospholipase domain containing 5.	0.804
APOA5	APOB	ENSSTOP00000017348	ENSSTOP00000020666	Apolipoprotein A5.	Apolipoprotein B.	0.852
APOA5	APOC3	ENSSTOP00000017348	ENSSTOP00000022848	Apolipoprotein A5.	Apolipoprotein C3.	0.888
APOA5	APOH	ENSSTOP00000017348	ENSSTOP00000023576	Apolipoprotein A5.	Apolipoprotein H.	0.871
APOA5	Dbi	ENSSTOP00000017348	ENSSTOP00000006039	Apolipoprotein A5.	ACB domain-containing protein.	0.422