STRINGSTRING
SOCS2 SOCS2 MT-CO2 MT-CO2 LOC101978336 LOC101978336 Anxa2 Anxa2 VDR VDR SCNN1B SCNN1B ATP2B2 ATP2B2 TRPC1 TRPC1 NME1 NME1 DDR1 DDR1 CELSR2 CELSR2 KCNMA1 KCNMA1 ENSSTOP00000025025 ENSSTOP00000025025 NCOR2 NCOR2 COPA COPA CYBA CYBA TRAF3IP2 TRAF3IP2 ANO1 ANO1 PAM PAM USF2 USF2 TP73 TP73 FOXB1 FOXB1 ADORA1 ADORA1 CHRM3 CHRM3 RAB14 RAB14 LOC101967640 LOC101967640 CEL CEL SLC6A3 SLC6A3 ZBTB7B ZBTB7B NEURL1 NEURL1 FGF10 FGF10 MED1 MED1 Kcnn4 Kcnn4 CAV1 CAV1 ATG5 ATG5 CREB1 CREB1 CHUK CHUK ATP7B ATP7B SLC29A2 SLC29A2 GHRHR GHRHR Aqp1 Aqp1 LOC101967926 LOC101967926 AQP4 AQP4 GPAT4 GPAT4 PRKCE PRKCE CRADD CRADD XDH XDH NPR3 NPR3 CDO1 CDO1 UCN UCN Rplp0 Rplp0 AQP5 AQP5 APRT APRT EIF2AK3 EIF2AK3 AGR2 AGR2 PRLR PRLR STAT5A STAT5A STAT5B STAT5B Traf3ip2 Traf3ip2 VAMP8 VAMP8 UMPS UMPS KALRN KALRN Hif1a Hif1a CHRM1 CHRM1 SLC29A1 SLC29A1 ATP7A ATP7A HK2 HK2 SLC4A5 SLC4A5 EDN1 EDN1 CCND1 CCND1 ERBB4 ERBB4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SOCS2Suppressor of cytokine signaling 2. (159 aa)
MT-CO2Cytochrome c oxidase subunit 2; Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. Subunit 2 transfers the electrons from cytochrome c via its binuclear copper A center to the bimetallic center of the catalytic subunit 1. (227 aa)
LOC10197833660S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (300 aa)
Anxa2Annexin. (339 aa)
VDRVitamin D receptor. (423 aa)
SCNN1BSodium channel epithelial 1 beta subunit; Belongs to the amiloride-sensitive sodium channel (TC 1.A.6) family. (640 aa)
ATP2B2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1243 aa)
TRPC1Transient receptor potential cation channel subfamily C member 1; Belongs to the transient receptor (TC 1.A.4) family. (748 aa)
NME1Nucleoside diphosphate kinase. (152 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (915 aa)
CELSR2Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2910 aa)
KCNMA1Potassium calcium-activated channel subfamily M alpha 1. (1219 aa)
ENSSTOP0000002502560S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (286 aa)
NCOR2Nuclear receptor corepressor 2. (2447 aa)
COPACoatomer subunit alpha; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. (1221 aa)
CYBACytochrome b-245 light chain; Critical component of the membrane-bound oxidase of phagocytes that generates superoxide. Associates with NOX3 to form a functional NADPH oxidase constitutively generating superoxide. (195 aa)
TRAF3IP2TRAF3 interacting protein 2. (476 aa)
ANO1Anoctamin. (997 aa)
PAMPeptidylglycine alpha-amidating monooxygenase. (979 aa)
USF2Upstream transcription factor 2, c-fos interacting. (344 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (634 aa)
FOXB1Forkhead box B1. (325 aa)
ADORA1Adenosine receptor A1; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (326 aa)
CHRM3Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (590 aa)
RAB14RAB14, member RAS oncogene family. (215 aa)
LOC101967640Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (125 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (558 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (587 aa)
ZBTB7BZinc finger and BTB domain containing 7B. (539 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (574 aa)
FGF10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (210 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa)
Kcnn4CaMBD domain-containing protein. (167 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa)
CREB1cAMP responsive element binding protein 1. (341 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
ATP7BATPase copper transporting beta. (1464 aa)
SLC29A2Solute carrier family 29 member 2. (458 aa)
GHRHRGrowth hormone releasing hormone receptor; Belongs to the G-protein coupled receptor 2 family. (423 aa)
Aqp1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
LOC101967926Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (124 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (316 aa)
GPAT4Glycerol-3-phosphate acyltransferase 4. (456 aa)
PRKCEProtein kinase C epsilon type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays essential roles in the regulation of multiple cellular processes linked to cytoskeletal proteins, such as cell adhesion, motility, migration and cell cycle, functions in neuron growth and ion channel regulation, and is involved in immune response, cancer cell invasion and regulation of apoptosis. Mediates cell adhesion to the extracellular matrix via integrin- dependent signaling, by mediating angiotensin-2-induced activation of integrin beta- [...] (737 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
XDHXanthine dehydrogenase. (1300 aa)
NPR3Natriuretic peptide receptor 3. (535 aa)
CDO1Cysteine dioxygenase. (200 aa)
UCNUrocortin. (127 aa)
Rplp060S acidic ribosomal protein P0; Ribosomal protein P0 is the functional equivalent of E.coli protein L10. (317 aa)
AQP5Aquaporin 5; Belongs to the MIP/aquaporin (TC 1.A.8) family. (256 aa)
APRTAdenine phosphoribosyltransferase. (180 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1005 aa)
AGR2Anterior gradient 2, protein disulphide isomerase family member. (175 aa)
PRLRProlactin receptor; This is a receptor for the anterior pituitary hormone prolactin. (616 aa)
STAT5ASignal transducer and activator of transcription. (773 aa)
STAT5BSignal transducer and activator of transcription. (765 aa)
Traf3ip2SEFIR domain-containing protein. (109 aa)
VAMP8Vesicle associated membrane protein 8. (141 aa)
UMPSUridine monophosphate synthetase. (480 aa)
KALRNKalirin RhoGEF kinase. (2951 aa)
Hif1aUncharacterized protein. (821 aa)
CHRM1Muscarinic acetylcholine receptor; The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. (460 aa)
SLC29A1Solute carrier family 29 member 1 (Augustine blood group). (263 aa)
ATP7AATPase copper transporting alpha. (1495 aa)
HK2Hexokinase 2. (917 aa)
SLC4A5Anion exchange protein. (1114 aa)
EDN1Endothelin 1. (202 aa)
CCND1Cyclin D1. (250 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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