STRINGSTRING
EZR EZR ENSSTOP00000030003 ENSSTOP00000030003 LYN LYN RGS8 RGS8 GNAZ GNAZ JUP JUP MTSS1 MTSS1 CHMP4A CHMP4A IQGAP1 IQGAP1 LOC101967288 LOC101967288 Gnas Gnas TNK2 TNK2 PTPN4 PTPN4 TRAF5 TRAF5 PTPRC PTPRC ESYT1 ESYT1 LOC101963239 LOC101963239 MYH10 MYH10 MCF2L MCF2L KCNAB2 KCNAB2 ATP2A2 ATP2A2 DLG4 DLG4 CDK16 CDK16 PTPN3 PTPN3 ESYT2 ESYT2 RASA3 RASA3 KCNAB1 KCNAB1 Gng10 Gng10 GM2A GM2A Myzap Myzap AKAP5 AKAP5 GNG7 GNG7 GNA15 GNA15 CAV2 CAV2 TH TH GNAT3 GNAT3 HIP1 HIP1 TRAF1 TRAF1 GNA12 GNA12 LDLRAP1 LDLRAP1 ASPSCR1 ASPSCR1 GNA11 GNA11 ATP2C2 ATP2C2 G6PD G6PD SAMD12 SAMD12 LITAF LITAF MIEN1 MIEN1 PTPN7 PTPN7 Snx18 Snx18 ALOX15 ALOX15 SHANK3 SHANK3 Cabp1 Cabp1 I3N418_ICTTR I3N418_ICTTR MTSS2 MTSS2 MAPT MAPT MYH9 MYH9 DSG1 DSG1 GNG8 GNG8 I3MXS8_ICTTR I3MXS8_ICTTR Ppp1r9b Ppp1r9b RYR1 RYR1 CBY3 CBY3 FGR FGR I3MUP6_ICTTR I3MUP6_ICTTR GNAQ GNAQ PTEN PTEN MDP1 MDP1 GNG2 GNG2 GNB2 GNB2 EXOC1 EXOC1 SRC SRC I3MRS9_ICTTR I3MRS9_ICTTR CHUK CHUK GNAT1 GNAT1 GNG4 GNG4 GNB3 GNB3 SNX5 SNX5 SPTA1 SPTA1 Diablo Diablo FES FES RYR2 RYR2 C2cd2l C2cd2l SNAP25 SNAP25 GNB5 GNB5 STAC3 STAC3 MSN MSN CHMP4C CHMP4C ANK1 ANK1 ESYT3 ESYT3 SLA SLA GNAI1 GNAI1 NPHS2 NPHS2 TRAF2 TRAF2 LCK LCK CNR2 CNR2 PPP3CA PPP3CA GNAL GNAL PRMT8 PRMT8 RAB21 RAB21 OSBPL2 OSBPL2 Racgap1 Racgap1 STAC2 STAC2 ZAP70 ZAP70 GEM GEM SNX9 SNX9 GNB1 GNB1 FRK FRK CYLD CYLD ERRFI1 ERRFI1 GNG11 GNG11 GNGT1 GNGT1 GRAMD2A GRAMD2A PGM5 PGM5 GNAT2 GNAT2 GNA14 GNA14 GNG5 GNG5 FERMT2 FERMT2 SRMS SRMS PTK6 PTK6 S100A6 S100A6 Gnao1 Gnao1 PKP4 PKP4 TNK1 TNK1 GNGT2 GNGT2 FYN FYN TRAF6 TRAF6 RAC1 RAC1 FARP1 FARP1 SLC4A1 SLC4A1 STAC STAC TIAM1 TIAM1 IKBKB IKBKB SYK SYK Birc2 Birc2 Tgm3 Tgm3 CHMP4B CHMP4B GNB4 GNB4 HCK HCK CYTH1 CYTH1 GNG12 GNG12 RGS1 RGS1 PLEKHA4 PLEKHA4 GNG13 GNG13 KCNIP1 KCNIP1 CD2 CD2 GRAMD1A GRAMD1A RGS2 RGS2 Map2k2 Map2k2 Rnf31 Rnf31 SYAP1 SYAP1 GNA13 GNA13 GPHN GPHN GNG3 GNG3 STYK1 STYK1 KIT KIT TRAF3 TRAF3 FER FER BLK BLK FGFR3 FGFR3 CDH1 CDH1 LOC101971017 LOC101971017 SAMD10 SAMD10 Acp1 Acp1 CYTH3 CYTH3 ATP2B1 ATP2B1 PTK2 PTK2 Gng14 Gng14 PTK2B PTK2B HTRA2 HTRA2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EZREzrin. (604 aa)
ENSSTOP00000030003Uncharacterized protein. (546 aa)
LYNTyrosine-protein kinase. (512 aa)
RGS8Regulator of G protein signaling 8. (180 aa)
GNAZG protein subunit alpha z. (355 aa)
JUPJunction plakoglobin. (780 aa)
MTSS1MTSS I-BAR domain containing 1. (759 aa)
CHMP4ACharged multivesicular body protein 4A. (259 aa)
IQGAP1IQ motif containing GTPase activating protein 1. (1657 aa)
LOC101967288Uncharacterized protein. (848 aa)
GnasUncharacterized protein. (244 aa)
TNK2Tyrosine kinase non receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1055 aa)
PTPN4Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (926 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (558 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1180 aa)
ESYT1Extended synaptotagmin 1. (1106 aa)
LOC101963239Uncharacterized protein. (556 aa)
MYH10Myosin heavy chain 10; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2007 aa)
MCF2LMCF.2 cell line derived transforming sequence like. (1127 aa)
KCNAB2Potassium voltage-gated channel subfamily A regulatory beta subunit 2. (343 aa)
ATP2A2Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1042 aa)
DLG4Discs large MAGUK scaffold protein 4; Belongs to the MAGUK family. (767 aa)
CDK16Cyclin dependent kinase 16; Belongs to the protein kinase superfamily. (496 aa)
PTPN3Tyrosine-protein phosphatase non-receptor type; May act at junctions between the membrane and the cytoskeleton. (882 aa)
ESYT2Extended synaptotagmin 2. (738 aa)
RASA3RAS p21 protein activator 3. (834 aa)
KCNAB1Potassium voltage-gated channel subfamily A member regulatory beta subunit 1. (385 aa)
Gng10Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GM2AGM2 ganglioside activator. (192 aa)
MyzapUncharacterized protein. (415 aa)
AKAP5A-kinase anchoring protein 5. (435 aa)
GNG7Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
GNA15G protein subunit alpha 15. (325 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
THTyrosine hydroxylase. (497 aa)
GNAT3G protein subunit alpha transducin 3. (354 aa)
HIP1Huntingtin interacting protein 1. (989 aa)
TRAF1TNF receptor-associated factor. (415 aa)
GNA12G protein subunit alpha 12. (343 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
ASPSCR1ASPSCR1 tether for SLC2A4, UBX domain containing. (508 aa)
GNA11G protein subunit alpha 11. (359 aa)
ATP2C2ATPase secretory pathway Ca2+ transporting 2; Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. (791 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (515 aa)
SAMD12Sterile alpha motif domain containing 12. (161 aa)
LITAFLipopolysaccharide induced TNF factor. (167 aa)
MIEN1Migration and invasion enhancer 1. (115 aa)
PTPN7Protein tyrosine phosphatase non-receptor type 7. (362 aa)
Snx18Sorting nexin. (618 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1645 aa)
Cabp1Uncharacterized protein. (241 aa)
I3N418_ICTTRGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (59 aa)
MTSS2MTSS I-BAR domain containing 2. (743 aa)
MAPTMicrotubule-associated protein. (430 aa)
MYH9Myosin heavy chain 9; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1960 aa)
DSG1Desmoglein 1; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (1098 aa)
GNG8Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (70 aa)
I3MXS8_ICTTRUncharacterized protein. (310 aa)
Ppp1r9bPDZ domain-containing protein. (361 aa)
RYR1Ryanodine receptor 1. (4864 aa)
CBY3Chibby family member 3. (212 aa)
FGRTyrosine-protein kinase. (527 aa)
I3MUP6_ICTTRGuanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
GNAQG protein subunit alpha q. (313 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
MDP1Uncharacterized protein. (164 aa)
GNG2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (71 aa)
GNB2G protein subunit beta 2. (371 aa)
EXOC1Exocyst complex component 1. (901 aa)
SRCTyrosine-protein kinase. (541 aa)
I3MRS9_ICTTRPDZ domain-containing protein. (197 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
GNAT1G protein subunit alpha transducin 1. (350 aa)
GNG4Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (77 aa)
GNB3G protein subunit beta 3. (340 aa)
SNX5Sorting nexin; Involved in several stages of intracellular trafficking. (394 aa)
SPTA1Spectrin alpha, erythrocytic 1. (2417 aa)
DiabloUncharacterized protein. (234 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
RYR2Ryanodine receptor 2. (4888 aa)
C2cd2lUncharacterized protein. (267 aa)
SNAP25Synaptosomal-associated protein; Belongs to the SNAP-25 family. (206 aa)
GNB5G protein subunit beta 5. (386 aa)
STAC3SH3 and cysteine rich domain 3. (362 aa)
MSNMoesin. (577 aa)
CHMP4CCharged multivesicular body protein 4C. (233 aa)
ANK1Ankyrin 1. (1913 aa)
ESYT3Extended synaptotagmin 3. (888 aa)
SLASrc like adaptor. (276 aa)
GNAI1G protein subunit alpha i1. (354 aa)
NPHS2NPHS2 stomatin family member, podocin. (382 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (501 aa)
LCKTyrosine-protein kinase. (521 aa)
CNR2Cannabinoid receptor 2; Belongs to the G-protein coupled receptor 1 family. (347 aa)
PPP3CASerine/threonine-protein phosphatase. (511 aa)
GNALG protein subunit alpha L. (378 aa)
PRMT8Protein arginine methyltransferase 8; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (369 aa)
RAB21RAB21, member RAS oncogene family. (221 aa)
OSBPL2Oxysterol-binding protein; Belongs to the OSBP family. (483 aa)
Racgap1Uncharacterized protein. (632 aa)
STAC2SH3 and cysteine rich domain 2. (408 aa)
ZAP70Tyrosine-protein kinase. (608 aa)
GEMGTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa)
SNX9Sorting nexin. (610 aa)
GNB1G protein subunit beta 1. (340 aa)
FRKTyrosine-protein kinase. (511 aa)
CYLDCYLD lysine 63 deubiquitinase; Belongs to the peptidase C19 family. (956 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (459 aa)
GNG11Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (73 aa)
GNGT1Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (74 aa)
GRAMD2AGRAM domain containing 2A. (318 aa)
PGM5Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (567 aa)
GNAT2G protein subunit alpha transducin 2. (354 aa)
GNA14G protein subunit alpha 14. (355 aa)
GNG5Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (68 aa)
FERMT2Fermitin family member 2. (680 aa)
SRMSTyrosine-protein kinase. (534 aa)
PTK6Tyrosine-protein kinase. (450 aa)
S100A6Protein S100; Belongs to the S-100 family. (92 aa)
Gnao1G protein subunit alpha o1. (344 aa)
PKP4Plakophilin 4. (1191 aa)
TNK1Tyrosine kinase non receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (662 aa)
GNGT2Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (69 aa)
FYNTyrosine-protein kinase. (537 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
RAC1Rac family small GTPase 1. (211 aa)
FARP1FERM, ARH/RhoGEF and pleckstrin domain protein 1. (1048 aa)
SLC4A1Anion exchange protein. (917 aa)
STACSH3 and cysteine rich domain. (402 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1567 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
SYKTyrosine-protein kinase. (626 aa)
Birc2Uncharacterized protein. (611 aa)
Tgm3TGc domain-containing protein. (697 aa)
CHMP4BCharged multivesicular body protein 4B. (224 aa)
GNB4G protein subunit beta 4. (340 aa)
HCKTyrosine-protein kinase. (502 aa)
CYTH1Cytohesin 1. (389 aa)
GNG12Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
RGS1Regulator of G protein signaling 1. (209 aa)
PLEKHA4Pleckstrin homology domain containing A4. (734 aa)
GNG13G protein subunit gamma 13. (67 aa)
KCNIP1Potassium voltage-gated channel interacting protein 1. (227 aa)
CD2CD2 molecule. (339 aa)
GRAMD1AGRAM domain containing 1A. (719 aa)
RGS2Regulator of G protein signaling 2. (211 aa)
Map2k2Mitogen-activated protein kinase kinase 2; Belongs to the protein kinase superfamily. (498 aa)
Rnf31Uncharacterized protein. (1071 aa)
SYAP1Synapse associated protein 1. (358 aa)
GNA13G protein subunit alpha 13. (306 aa)
GPHNMolybdopterin molybdenumtransferase; Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. (769 aa)
GNG3Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (75 aa)
STYK1Serine/threonine/tyrosine kinase 1. (328 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (566 aa)
FERTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa)
BLKTyrosine-protein kinase. (499 aa)
FGFR3Fibroblast growth factor receptor. (804 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
LOC101971017PX domain-containing protein. (498 aa)
SAMD10Sterile alpha motif domain containing 10. (202 aa)
Acp1LMWPc domain-containing protein. (143 aa)
CYTH3Cytohesin 3. (399 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa)
PTK2Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1137 aa)
Gng14Guanine nucleotide-binding protein subunit gamma; Guanine nucleotide-binding proteins (G proteins) are involved as a modulator or transducer in various transmembrane signaling systems. The beta and gamma chains are required for the GTPase activity, for replacement of GDP by GTP, and for G protein-effector interaction. (72 aa)
PTK2BProtein tyrosine kinase 2 beta. (968 aa)
HTRA2HtrA serine peptidase 2. (458 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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