STRINGSTRING
NEDD4L NEDD4L WNK4 WNK4 AKT2 AKT2 I3NC46_ICTTR I3NC46_ICTTR CHP2 CHP2 NOS1 NOS1 CNKSR3 CNKSR3 WNK2 WNK2 KIF5B KIF5B FGF14 FGF14 FXYD1 FXYD1 Gnas Gnas PRSS8 PRSS8 AKT1 AKT1 WNK3 WNK3 SCN5A SCN5A WNK1 WNK1 GPER1 GPER1 ENSSTOP00000032442 ENSSTOP00000032442 CNTN1 CNTN1 SCN3B SCN3B GLRX GLRX Sgk1 Sgk1 SCN4B SCN4B DRD4 DRD4 ATP1B2 ATP1B2 Dmd Dmd DNM2 DNM2 SCN1B SCN1B AHCYL1 AHCYL1 CHP1 CHP1 MLLT6 MLLT6 Atp1b3 Atp1b3 ATP1B1 ATP1B1 AKT3 AKT3 FGF12 FGF12 TESC TESC SLC9A1 SLC9A1 I3MQ94_ICTTR I3MQ94_ICTTR IKBKB IKBKB NKX2-5 NKX2-5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NEDD4LNEDD4 like E3 ubiquitin protein ligase. (962 aa)
WNK4WNK lysine deficient protein kinase 4. (1246 aa)
AKT2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (467 aa)
I3NC46_ICTTRNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (397 aa)
CHP2Calcineurin like EF-hand protein 2. (195 aa)
NOS1Nitric oxide synthase; Produces nitric oxide (NO). (1329 aa)
CNKSR3CNKSR family member 3. (547 aa)
WNK2WNK lysine deficient protein kinase 2. (2057 aa)
KIF5BKinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (963 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
FXYD1FXYD domain-containing ion transport regulator; Belongs to the FXYD family. (68 aa)
GnasUncharacterized protein. (244 aa)
PRSS8Serine protease 8; Belongs to the peptidase S1 family. (342 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
WNK3WNK lysine deficient protein kinase 3. (1745 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (2019 aa)
WNK1WNK lysine deficient protein kinase 1. (2635 aa)
GPER1G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (375 aa)
ENSSTOP00000032442ANK_REP_REGION domain-containing protein. (460 aa)
CNTN1Contactin 1. (627 aa)
SCN3BSodium voltage-gated channel beta subunit 3. (215 aa)
GLRXGlutaredoxin. (107 aa)
Sgk1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (454 aa)
SCN4BSodium voltage-gated channel beta subunit 4. (228 aa)
DRD4Dopamine receptor D4; Belongs to the G-protein coupled receptor 1 family. (374 aa)
ATP1B2Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (290 aa)
DmdUncharacterized protein. (1255 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
SCN1BSodium voltage-gated channel beta subunit 1. (210 aa)
AHCYL1Adenosylhomocysteinase like 1; Belongs to the adenosylhomocysteinase family. (530 aa)
CHP1Calcineurin like EF-hand protein 1. (195 aa)
MLLT6MLLT6, PHD finger containing. (1105 aa)
Atp1b3Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (265 aa)
ATP1B1Sodium/potassium-transporting ATPase subunit beta; This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. Belongs to the X(+)/potassium ATPases subunit beta family. (303 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
TESCTescalcin. (207 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (810 aa)
I3MQ94_ICTTRUncharacterized protein. (1171 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (756 aa)
NKX2-5NK2 homeobox 5. (321 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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