STRINGSTRING
RBPMS RBPMS ACVR1 ACVR1 LOC101967701 LOC101967701 SDCBP SDCBP ENG ENG TGFB1 TGFB1 BMP10 BMP10 BMP3 BMP3 INHA INHA BMP7 BMP7 PPARG PPARG NODAL NODAL CSNK2B CSNK2B TGFBR1 TGFBR1 BMPR1A BMPR1A TWSG1 TWSG1 SMAD4 SMAD4 ACVR2A ACVR2A BMP6 BMP6 GDF9 GDF9 GDF6 GDF6 BMP2 BMP2 GDF7 GDF7 GDF15 GDF15 INHBB INHBB INHBE INHBE TGFB3 TGFB3 GDF2 GDF2 GDF5 GDF5 GDF10 GDF10 LOC101961346 LOC101961346 GDF11 GDF11 Gdf1 Gdf1 TGFBR2 TGFBR2 Inhba Inhba ENSSTOP00000030884 ENSSTOP00000030884 DAB2 DAB2 Bmp8b Bmp8b LOC101962293 LOC101962293 ACVRL1 ACVRL1 ACVR1B ACVR1B INHBC INHBC BMP4 BMP4 TGFB2 TGFB2 MSTN MSTN GDF3 GDF3 BMPR2 BMPR2 BMP5 BMP5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
RBPMSRNA binding protein, mRNA processing factor. (219 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LOC101967701TGF_BETA_2 domain-containing protein. (397 aa)
SDCBPSyndecan binding protein. (298 aa)
ENGEndoglin. (463 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
BMP10Bone morphogenetic protein 10. (422 aa)
BMP3Bone morphogenetic protein 3. (487 aa)
INHAInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (368 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
NODALNodal growth differentiation factor. (350 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (248 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (223 aa)
SMAD4Mothers against decapentaplegic homolog. (552 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (521 aa)
BMP6Bone morphogenetic protein 6. (507 aa)
GDF9Growth differentiation factor 9. (449 aa)
GDF6Growth differentiation factor 6. (460 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
GDF7Growth differentiation factor 7. (445 aa)
GDF15Growth differentiation factor 15. (329 aa)
INHBBInhibin subunit beta B. (336 aa)
INHBEInhibin subunit beta E. (349 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
GDF2Growth differentiation factor 2. (429 aa)
GDF5Growth differentiation factor 5. (495 aa)
GDF10Bone morphogenetic protein 3; Belongs to the TGF-beta family. (472 aa)
LOC101961346Left-right determination factor. (363 aa)
GDF11Growth differentiation factor 11. (387 aa)
Gdf1TGF_BETA_2 domain-containing protein. (373 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
InhbaTGF_BETA_2 domain-containing protein. (133 aa)
ENSSTOP00000030884TGF_BETA_2 domain-containing protein. (272 aa)
DAB2DAB adaptor protein 2. (767 aa)
Bmp8bTGF_BETA_2 domain-containing protein. (252 aa)
LOC101962293Left-right determination factor. (367 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (512 aa)
INHBCInhibin subunit beta C. (352 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
MSTNMyostatin. (376 aa)
GDF3Growth differentiation factor 3. (360 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
BMP5Bone morphogenetic protein 5. (454 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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