STRINGSTRING
CYP26C1 CYP26C1 JAG1 JAG1 PDCD6 PDCD6 TFAP2A TFAP2A ZEB2 ZEB2 SEMA3C SEMA3C NRP2 NRP2 KITLG KITLG Cfl1 Cfl1 SEMA4A SEMA4A FAM172A FAM172A LOC101966144 LOC101966144 ERBB4 ERBB4 ALDH1A2 ALDH1A2 SEMA3G SEMA3G EDN1 EDN1 SEMA6C SEMA6C RADIL RADIL Cdc42 Cdc42 MAPK3 MAPK3 SEMA4D SEMA4D SEMA4F SEMA4F RET RET NOLC1 NOLC1 CDH2 CDH2 SEMA5A SEMA5A FN1 FN1 PAX6 PAX6 TBX1 TBX1 RDH10 RDH10 ACVR1 ACVR1 Hif1a Hif1a SEMA3D SEMA3D PHACTR4 PHACTR4 SEMA4C SEMA4C ANXA6 ANXA6 CITED2 CITED2 PAX3 PAX3 SOX8 SOX8 TCOF1 TCOF1 SEMA4G SEMA4G EDNRB EDNRB HTR2B HTR2B NRTN NRTN SEMA4B SEMA4B SEMA5B SEMA5B SEMA3E SEMA3E GBX2 GBX2 SMO SMO CORO1C CORO1C EDN3 EDN3 ISL1 ISL1 NRP1 NRP1 MAPK1 MAPK1 SEMA6D SEMA6D KLHL12 KLHL12 CYP26A1 CYP26A1 BMPR1A BMPR1A SEMA3F SEMA3F SHH SHH LAMA5 LAMA5 PEF1 PEF1 FOXC2 FOXC2 SOX10 SOX10 SEMA7A SEMA7A KBTBD8 KBTBD8 OVOL2 OVOL2 EFNB1 EFNB1 I3N4S4_ICTTR I3N4S4_ICTTR GDNF GDNF PHOX2B PHOX2B HES1 HES1 I3N6Q6_ICTTR I3N6Q6_ICTTR SNAI2 SNAI2 HAND2 HAND2 SOX9 SOX9 EDNRA EDNRA FGF19 FGF19 SEMA6B SEMA6B Pitx2 Pitx2 DICER1 DICER1 SEMA6A SEMA6A SEMA3B SEMA3B FOLR1 FOLR1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYP26C1Cytochrome P450 family 26 subfamily C member 1; Belongs to the cytochrome P450 family. (518 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
PDCD6Programmed cell death 6. (191 aa)
TFAP2ATranscription factor AP-2 alpha. (477 aa)
ZEB2Zinc finger E-box binding homeobox 2. (1249 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (926 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
Cfl1ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (203 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (758 aa)
FAM172AFamily with sequence similarity 172 member A. (416 aa)
LOC101966144Uncharacterized protein. (147 aa)
ERBB4Receptor protein-tyrosine kinase. (1308 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (773 aa)
EDN1Endothelin 1. (202 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (866 aa)
RADILRap associating with DIL domain. (1070 aa)
Cdc42Uncharacterized protein. (191 aa)
MAPK3Mitogen-activated protein kinase. (361 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (747 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1112 aa)
NOLC1Nucleolar and coiled-body phosphoprotein 1. (703 aa)
CDH2Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (920 aa)
SEMA5ASemaphorin 5A. (1074 aa)
FN1Fibronectin 1. (2474 aa)
PAX6Paired box 6. (436 aa)
TBX1T-box transcription factor 1. (406 aa)
RDH10Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa)
ACVR1Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
Hif1aUncharacterized protein. (821 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (735 aa)
PHACTR4Phosphatase and actin regulator. (712 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (831 aa)
ANXA6Annexin. (673 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (274 aa)
PAX3Paired box 3. (484 aa)
SOX8SRY-box transcription factor 8. (466 aa)
TCOF1Treacle ribosome biogenesis factor 1. (1455 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (839 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
HTR2B5-hydroxytryptamine receptor 2B. (480 aa)
NRTNNeurturin. (197 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (823 aa)
SEMA5BSemaphorin 5B. (1093 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (721 aa)
GBX2Gastrulation brain homeobox 2. (348 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (783 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (474 aa)
EDN3Endothelin 3. (197 aa)
ISL1ISL LIM homeobox 1. (349 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
MAPK1Mitogen-activated protein kinase. (331 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1061 aa)
KLHL12Kelch like family member 12. (568 aa)
CYP26A1Cytochrome P450 family 26 subfamily A member 1; Belongs to the cytochrome P450 family. (497 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
SHHSonic hedgehog signaling molecule. (370 aa)
LAMA5Laminin subunit alpha 5. (3474 aa)
PEF1Penta-EF-hand domain containing 1. (279 aa)
FOXC2Forkhead box C2. (500 aa)
SOX10SRY-box transcription factor 10. (466 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
KBTBD8Kelch repeat and BTB domain containing 8. (600 aa)
OVOL2Ovo like zinc finger 2. (276 aa)
EFNB1Ephrin B1; Belongs to the ephrin family. (345 aa)
I3N4S4_ICTTRUncharacterized protein. (162 aa)
GDNFGlial cell line-derived neurotrophic factor; Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high- affinity dopamine uptake. (212 aa)
PHOX2BPaired like homeobox 2B. (252 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
I3N6Q6_ICTTRADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family. (160 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
HAND2Heart and neural crest derivatives expressed 2. (217 aa)
SOX9SRY-box transcription factor 9. (509 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (801 aa)
Pitx2Homeobox protein. (325 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1904 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (778 aa)
FOLR1Folate receptor alpha. (255 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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