88 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LRP5	Uncharacterized protein. (1516 aa)
	HK1	Hexokinase 1. (920 aa)
	AOAH	Acyloxyacyl hydrolase. (587 aa)
	PKM	Pyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
	ENSSTOP00000030853	P-type domain-containing protein. (219 aa)
	PKLR	Pyruvate kinase; Belongs to the pyruvate kinase family. (565 aa)
	PFKFB2	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2. (556 aa)
	LOC101972267	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (275 aa)
	CTBS	Chitobiase; Belongs to the glycosyl hydrolase 18 family. (381 aa)
	GALT	Galactose-1-phosphate uridylyltransferase. (379 aa)
	ENSSTOP00000027444	Uncharacterized protein; Belongs to the LDH/MDH superfamily. (301 aa)
	ENO2	Enolase 2. (434 aa)
	TKFC	Triokinase and FMN cyclase. (578 aa)
	KHK	Ketohexokinase. (343 aa)
	ENSSTOP00000025862	Uncharacterized protein. (299 aa)
	LOC101967464	Uncharacterized protein. (194 aa)
	Gk	Uncharacterized protein; Belongs to the FGGY kinase family. (559 aa)
	PYGM	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (842 aa)
	GALE	UDP-glucose 4-epimerase; Belongs to the NAD(P)-dependent epimerase/dehydratase family. (348 aa)
	IDNK	Gluconokinase; Belongs to the gluconokinase GntK/GntV family. (174 aa)
	GM2A	GM2 ganglioside activator. (192 aa)
	LOC101965577	Gp_dh_N domain-containing protein; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family. (325 aa)
	PFKL	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	PGAM1	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
	MPPED1	Metallophosphoesterase domain containing 1. (286 aa)
	NAGA	Alpha-galactosidase. (423 aa)
	MIOX	Myo-inositol oxygenase. (285 aa)
	TPI1	Triosephosphate isomerase. (299 aa)
	BPGM	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (258 aa)
	TKTL2	Transketolase like 2. (627 aa)
	NEU2	Neuraminidase 2. (388 aa)
	ADRB1	Adrenoceptor beta 1. (418 aa)
	G6PC	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (357 aa)
	NUDT5	Nudix hydrolase 5; Belongs to the Nudix hydrolase family. (198 aa)
	DHTKD1	Dehydrogenase E1 and transketolase domain containing 1. (921 aa)
	MPPED2	Metallophosphoesterase domain containing 2. (294 aa)
	TREH	Trehalase. (579 aa)
	PYGB	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (843 aa)
	DHDH	Dihydrodiol dehydrogenase. (333 aa)
	LCT	Lactase. (1928 aa)
	SI	Sucrase-isomaltase. (1629 aa)
	GK5	Glycerol kinase 5; Belongs to the FGGY kinase family. (511 aa)
	GALK1	Galactokinase 1. (392 aa)
	NEU1	Neuraminidase 1. (416 aa)
	NEU3	Neuraminidase 3. (435 aa)
	RBKS	Ribokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (322 aa)
	STBD1	Starch binding domain 1. (348 aa)
	ENO1	Enolase 1. (434 aa)
	PYGL	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (851 aa)
	GLB1	Beta-galactosidase. (668 aa)
	GUSB	Beta-glucuronidase; Plays an important role in the degradation of dermatan and keratan sulfates; Belongs to the glycosyl hydrolase 2 family. (575 aa)
	SORD	Sorbitol dehydrogenase. (357 aa)
	PGAM2	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (253 aa)
	BAD	BCL2 associated agonist of cell death. (208 aa)
	PGM2	Phosphoglucomutase 2. (617 aa)
	HEXB	Beta-hexosaminidase. (538 aa)
	Gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (346 aa)
	G6PC2	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (355 aa)
	GAPDHS	Glyceraldehyde-3-phosphate dehydrogenase. (413 aa)
	ALDOB	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	PRKAG3	Protein kinase AMP-activated non-catalytic subunit gamma 3. (490 aa)
	PFKP	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (791 aa)
	MAN2C1	Mannosidase alpha class 2C member 1. (1039 aa)
	GPD2	Glycerol-3-phosphate dehydrogenase; Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family. (727 aa)
	TKTL1	Transketolase like 1. (596 aa)
	PHKG2	Phosphorylase kinase catalytic subunit gamma 2; Belongs to the protein kinase superfamily. (406 aa)
	HK3	Hexokinase 3. (867 aa)
	FOXK2	Forkhead box K2. (596 aa)
	MGAM	Maltase-glucoamylase. (1489 aa)
	RB1CC1	RB1 inducible coiled-coil 1. (1593 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (472 aa)
	GCK	Phosphotransferase. (467 aa)
	I3M0U3_ICTTR	Uncharacterized protein; Belongs to the glycosyl hydrolase 31 family. (270 aa)
	ENO4	Enolase 4. (620 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
	HK2	Hexokinase 2. (917 aa)
	Pgk1	Phosphoglycerate kinase. (417 aa)
	PFKM	ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (780 aa)
	ABHD10	Abhydrolase domain containing 10. (303 aa)
	PGD	6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
	DERA	Deoxyribose-phosphate aldolase. (318 aa)
	Aldoa	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (417 aa)
	ENO3	Enolase 3. (434 aa)
	FOXK1	Forkhead box K1. (608 aa)
	ALDOC	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
	HKDC1	Hexokinase domain containing 1. (917 aa)
	OGDH	Oxoglutarate dehydrogenase. (1023 aa)
	Ldha	L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ABHD10	PRKAG3	ENSSTOP00000001160	ENSSTOP00000005927	Abhydrolase domain containing 10.	Protein kinase AMP-activated non-catalytic subunit gamma 3.	0.498
ABHD10	SORD	ENSSTOP00000001160	ENSSTOP00000007803	Abhydrolase domain containing 10.	Sorbitol dehydrogenase.	0.466
ADRB1	HTR2A	ENSSTOP00000018161	ENSSTOP00000002559	Adrenoceptor beta 1.	5-hydroxytryptamine receptor 2A.	0.532
ALDOB	ALDOC	ENSSTOP00000006281	ENSSTOP00000000485	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.897
ALDOB	Aldoa	ENSSTOP00000006281	ENSSTOP00000000776	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	0.905
ALDOB	BPGM	ENSSTOP00000006281	ENSSTOP00000020627	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.903
ALDOB	DERA	ENSSTOP00000006281	ENSSTOP00000000862	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Deoxyribose-phosphate aldolase.	0.847
ALDOB	ENO1	ENSSTOP00000006281	ENSSTOP00000010782	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Enolase 1.	0.918
ALDOB	ENO2	ENSSTOP00000006281	ENSSTOP00000027044	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Enolase 2.	0.918
ALDOB	ENO3	ENSSTOP00000006281	ENSSTOP00000000606	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Enolase 3.	0.923
ALDOB	ENO4	ENSSTOP00000006281	ENSSTOP00000002347	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Enolase 4.	0.918
ALDOB	ENSSTOP00000025862	ENSSTOP00000006281	ENSSTOP00000025862	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Uncharacterized protein.	0.600
ALDOB	ENSSTOP00000027444	ENSSTOP00000006281	ENSSTOP00000027444	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Uncharacterized protein; Belongs to the LDH/MDH superfamily.	0.843
ALDOB	G6PC	ENSSTOP00000006281	ENSSTOP00000016360	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.841
ALDOB	G6PC2	ENSSTOP00000006281	ENSSTOP00000006648	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family.	0.841
ALDOB	GAPDHS	ENSSTOP00000006281	ENSSTOP00000006574	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.935
ALDOB	GCK	ENSSTOP00000006281	ENSSTOP00000002448	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Phosphotransferase.	0.865
ALDOB	GPI	ENSSTOP00000006281	ENSSTOP00000002308	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Glucose-6-phosphate isomerase; Belongs to the GPI family.	0.955
ALDOB	Gapdh	ENSSTOP00000006281	ENSSTOP00000006739	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Glyceraldehyde-3-phosphate dehydrogenase.	0.914
ALDOB	HK1	ENSSTOP00000006281	ENSSTOP00000032607	Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family.	Hexokinase 1.	0.865