(15 nodes) Regulation of striated muscle tissue development network (Ictidomys tridecemlineatus)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	FGF8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
	LEF1	Lymphoid enhancer binding factor 1. (399 aa)
	MRTFB	Myocardin related transcription factor B. (1081 aa)
	CREB1	cAMP responsive element binding protein 1. (341 aa)
	LOX	Lysyl oxidase. (397 aa)
	LUC7L	LUC7 like. (371 aa)
	SMAD3	Mothers against decapentaplegic homolog. (425 aa)
	SOX15	SRY-box transcription factor 15. (249 aa)
	HDAC7	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (956 aa)
	BMP4	Bone morphogenetic protein 4. (409 aa)
	FGF3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (220 aa)
	SIRT2	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa)
	ERBB3	Erb-b2 receptor tyrosine kinase 3. (1248 aa)
	CENPF	Centromere protein F. (2997 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMP4	FGF8	ENSSTOP00000001023	ENSSTOP00000027210	Bone morphogenetic protein 4.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.573
BMP4	LEF1	ENSSTOP00000001023	ENSSTOP00000032586	Bone morphogenetic protein 4.	Lymphoid enhancer binding factor 1.	0.441
BMP4	SMAD3	ENSSTOP00000001023	ENSSTOP00000009229	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.725
CREB1	SMAD3	ENSSTOP00000014755	ENSSTOP00000009229	cAMP responsive element binding protein 1.	Mothers against decapentaplegic homolog.	0.562
ERBB3	FGF3	ENSSTOP00000023609	ENSSTOP00000020960	Erb-b2 receptor tyrosine kinase 3.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.855
ERBB3	FGF8	ENSSTOP00000023609	ENSSTOP00000027210	Erb-b2 receptor tyrosine kinase 3.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.854
FGF3	ERBB3	ENSSTOP00000020960	ENSSTOP00000023609	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Erb-b2 receptor tyrosine kinase 3.	0.855
FGF3	FGF8	ENSSTOP00000020960	ENSSTOP00000027210	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.831
FGF3	TGFB1	ENSSTOP00000020960	ENSSTOP00000008874	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.453
FGF8	BMP4	ENSSTOP00000027210	ENSSTOP00000001023	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Bone morphogenetic protein 4.	0.573
FGF8	ERBB3	ENSSTOP00000027210	ENSSTOP00000023609	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Erb-b2 receptor tyrosine kinase 3.	0.854
FGF8	FGF3	ENSSTOP00000027210	ENSSTOP00000020960	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.831
FGF8	TGFB1	ENSSTOP00000027210	ENSSTOP00000008874	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.451
HDAC7	LEF1	ENSSTOP00000001667	ENSSTOP00000032586	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	Lymphoid enhancer binding factor 1.	0.478
HDAC7	SIRT2	ENSSTOP00000001667	ENSSTOP00000021109	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	0.469
LEF1	BMP4	ENSSTOP00000032586	ENSSTOP00000001023	Lymphoid enhancer binding factor 1.	Bone morphogenetic protein 4.	0.441
LEF1	HDAC7	ENSSTOP00000032586	ENSSTOP00000001667	Lymphoid enhancer binding factor 1.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.478
LEF1	SMAD3	ENSSTOP00000032586	ENSSTOP00000009229	Lymphoid enhancer binding factor 1.	Mothers against decapentaplegic homolog.	0.825
LEF1	SOX15	ENSSTOP00000032586	ENSSTOP00000005049	Lymphoid enhancer binding factor 1.	SRY-box transcription factor 15.	0.566
SIRT2	HDAC7	ENSSTOP00000021109	ENSSTOP00000001667	NAD-dependent protein deacetylase; NAD-dependent protein deacetylase.	Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.	0.469