STRINGSTRING
LIPI LIPI PLCH1 PLCH1 DDHD1 DDHD1 PROCA1 PROCA1 Pla2g4b Pla2g4b PLCL2 PLCL2 GDPD3 GDPD3 PLA2G4C PLA2G4C LPL LPL PLCD1 PLCD1 ENPP2 ENPP2 PLA2G3 PLA2G3 PNLIP PNLIP PLA1A PLA1A PLA2G1B PLA2G1B PLD6 PLD6 SMPDL3B SMPDL3B SEC23IP SEC23IP PLCG2 PLCG2 ABHD2 ABHD2 NOTUM NOTUM PLB1 PLB1 DAGLB DAGLB TMEM8B TMEM8B PLA2G12A PLA2G12A PLBD2 PLBD2 PLA2G10 PLA2G10 GDPD1 GDPD1 PLA2G12B PLA2G12B GDE1 GDE1 PNLIPRP1 PNLIPRP1 PNLIPRP2 PNLIPRP2 SMPD1 SMPD1 PLA2G2D PLA2G2D PLCD3 PLCD3 PLA2G7 PLA2G7 PLD1 PLD1 PLCZ1 PLCZ1 Oc90 Oc90 LIPH LIPH LOC101971868 LOC101971868 Lipe Lipe FAAH FAAH PLCG1 PLCG1 LYPLA2 LYPLA2 ABHD12B ABHD12B I3MIY0_ICTTR I3MIY0_ICTTR PLA2G2E PLA2G2E ABHD16A ABHD16A PLBD1 PLBD1 PLA2G15 PLA2G15 SMPD3 SMPD3 ENPP7 ENPP7 PNPLA3 PNPLA3 PLA2G4E PLA2G4E PLA2G4D PLA2G4D PLA2G4F PLA2G4F ABHD12 ABHD12 PNPLA7 PNPLA7 PLD2 PLD2 PRDX6 PRDX6 ABHD6 ABHD6 LIPG LIPG PLCB1 PLCB1 PNPLA6 PNPLA6 ABHD3 ABHD3 LOC101973014 LOC101973014 PLCH2 PLCH2 LDAH LDAH CCR1 CCR1 PLCE1 PLCE1 LCAT LCAT LOC101956324 LOC101956324 PNPLA4 PNPLA4 LOC101971249 LOC101971249 ABHD16B ABHD16B ASPG ASPG I3N030_ICTTR I3N030_ICTTR Smpd5 Smpd5 PLA2G2A PLA2G2A SMPD4 SMPD4 PNPLA5 PNPLA5 PLCL1 PLCL1 MGLL MGLL FAAH2 FAAH2 PLAAT3 PLAAT3 CEL CEL TM7SF3 TM7SF3 NAPEPLD NAPEPLD ABHD1 ABHD1 LIPA LIPA I3NFT9_ICTTR I3NFT9_ICTTR PNPLA1 PNPLA1 LOC106145384 LOC106145384 PLA2G2F PLA2G2F GPLD1 GPLD1 PLCD4 PLCD4 PLCB4 PLCB4 DDHD2 DDHD2 ABHD4 ABHD4 ABHD15 ABHD15 PNPLA2 PNPLA2 HMOX1 HMOX1 PLA2G5 PLA2G5 DAGLA DAGLA PLCB2 PLCB2 PNPLA8 PNPLA8 PITPNM3 PITPNM3 LYPLA1 LYPLA1 SMPD2 SMPD2 Kiaa0895 Kiaa0895 PLCB3 PLCB3 LIPC LIPC PLA2G4A PLA2G4A PLA2G6 PLA2G6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LIPILipase I. (415 aa)
PLCH1Phosphoinositide phospholipase C. (1685 aa)
DDHD1DDHD domain containing 1. (796 aa)
PROCA1Protein interacting with cyclin A1. (374 aa)
Pla2g4bPhospholipase A2. (774 aa)
PLCL2Phosphoinositide phospholipase C. (1100 aa)
GDPD3Glycerophosphodiester phosphodiesterase domain containing 3. (331 aa)
PLA2G4CPhospholipase A2 group IVC. (571 aa)
LPLLipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (473 aa)
PLCD1Phosphoinositide phospholipase C. (756 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
PLA2G3Phospholipase A2 group III. (626 aa)
PNLIPPancreatic triacylglycerol lipase; Plays an important role in fat metabolism. It preferentially splits the esters of long-chain fatty acids at positions 1 and 3, producing mainly 2-monoacylglycerol and free fatty acids, and shows considerably higher activity against insoluble emulsified substrates than against soluble ones (By similarity). Plays a role in hibernation as a key enzyme that shows high activity at low temperatures. When expressed in the hibernating heart it liberates fatty acids from triglycerides at temperatures as low as 0 degrees Celsius. (465 aa)
PLA1APhospholipase A1 member A. (456 aa)
PLA2G1BPhospholipase A(2). (117 aa)
PLD6Phospholipase D family member 6. (222 aa)
SMPDL3BAcid sphingomyelinase-like phosphodiesterase. (456 aa)
SEC23IPSEC23 interacting protein. (1001 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1267 aa)
ABHD2Abhydrolase domain containing 2. (425 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (503 aa)
PLB1Phospholipase B1. (1442 aa)
DAGLBDiacylglycerol lipase beta. (672 aa)
TMEM8BTransmembrane protein 8B. (896 aa)
PLA2G12APhospholipase A2 group XIIA. (189 aa)
PLBD2Phospholipase B-like; Putative phospholipase. (589 aa)
PLA2G10Phospholipase A(2). (148 aa)
GDPD1Glycerophosphodiester phosphodiesterase domain containing 1. (314 aa)
PLA2G12BPhospholipase A2 group XIIB. (195 aa)
GDE1Glycerophosphodiester phosphodiesterase 1. (328 aa)
PNLIPRP1Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (473 aa)
PNLIPRP2Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (481 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
PLA2G2DPhospholipase A(2). (145 aa)
PLCD3Phosphoinositide phospholipase C. (782 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (443 aa)
PLD1Phospholipase. (1037 aa)
PLCZ1Phosphoinositide phospholipase C. (594 aa)
Oc90Uncharacterized protein. (483 aa)
LIPHLipase H. (444 aa)
LOC101971868Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (566 aa)
LipeHormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. (763 aa)
FAAHFatty acid amide hydrolase. (579 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
LYPLA2Lysophospholipase 2. (231 aa)
ABHD12BAbhydrolase domain containing 12B. (359 aa)
I3MIY0_ICTTRUncharacterized protein. (238 aa)
PLA2G2EPhospholipase A(2). (142 aa)
ABHD16AAbhydrolase domain containing 16A. (558 aa)
PLBD1Phospholipase B-like; Putative phospholipase. (494 aa)
PLA2G15Phospholipase A2 group XV. (413 aa)
SMPD3Sphingomyelin phosphodiesterase 3. (655 aa)
ENPP7Ectonucleotide pyrophosphatase/phosphodiesterase 7. (427 aa)
PNPLA3Patatin like phospholipase domain containing 3. (420 aa)
PLA2G4EPhospholipase A2. (876 aa)
PLA2G4DPhospholipase A2. (827 aa)
PLA2G4FPhospholipase A2. (840 aa)
ABHD12Abhydrolase domain containing 12. (397 aa)
PNPLA7Patatin like phospholipase domain containing 7. (1354 aa)
PLD2Phospholipase. (933 aa)
PRDX6Peroxiredoxin 6. (224 aa)
ABHD6Abhydrolase domain containing 6. (337 aa)
LIPGLipase G, endothelial type. (500 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1216 aa)
PNPLA6Patatin like phospholipase domain containing 6. (1326 aa)
ABHD3Abhydrolase domain containing 3. (338 aa)
LOC101973014Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (565 aa)
PLCH2Phosphoinositide phospholipase C. (1480 aa)
LDAHLipid droplet associated hydrolase. (325 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
PLCE1Phosphoinositide phospholipase C. (2298 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
LOC101956324Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (536 aa)
PNPLA4Patatin like phospholipase domain containing 4. (253 aa)
LOC101971249Uncharacterized protein. (298 aa)
ABHD16BAbhydrolase domain containing 16B. (466 aa)
ASPGAsparaginase. (564 aa)
I3N030_ICTTRLRAT domain-containing protein. (241 aa)
Smpd5Endo/exonuclease/phosphatase domain-containing protein. (472 aa)
PLA2G2APhospholipase A(2). (145 aa)
SMPD4Sphingomyelin phosphodiesterase 4. (827 aa)
PNPLA5Patatin like phospholipase domain containing 5. (389 aa)
PLCL1Phosphoinositide phospholipase C. (1096 aa)
MGLLMonoglyceride lipase. (311 aa)
FAAH2Fatty acid amide hydrolase 2. (491 aa)
PLAAT3Phospholipase A and acyltransferase 3. (189 aa)
CELCarboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (558 aa)
TM7SF3Transmembrane 7 superfamily member 3. (570 aa)
NAPEPLDN-acyl phosphatidylethanolamine phospholipase D. (400 aa)
ABHD1Abhydrolase domain containing 1. (405 aa)
LIPALipase; Belongs to the AB hydrolase superfamily. Lipase family. (397 aa)
I3NFT9_ICTTRCOesterase domain-containing protein. (179 aa)
PNPLA1Patatin like phospholipase domain containing 1. (515 aa)
LOC106145384Carboxylic ester hydrolase; Belongs to the type-B carboxylesterase/lipase family. (495 aa)
PLA2G2FPhospholipase A(2). (209 aa)
GPLD1Glycosylphosphatidylinositol specific phospholipase D1. (896 aa)
PLCD4Phosphoinositide phospholipase C. (783 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1206 aa)
DDHD2DDHD domain containing 2. (701 aa)
ABHD4Abhydrolase domain containing 4. (355 aa)
ABHD15Abhydrolase domain containing 15. (474 aa)
PNPLA2Patatin like phospholipase domain containing 2. (489 aa)
HMOX1Heme oxygenase 1. (288 aa)
PLA2G5Phospholipase A(2). (161 aa)
DAGLADiacylglycerol lipase alpha. (1042 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1182 aa)
PNPLA8Patatin like phospholipase domain containing 8. (692 aa)
PITPNM3PITPNM family member 3. (973 aa)
LYPLA1Lysophospholipase 1. (230 aa)
SMPD2Sphingomyelin phosphodiesterase 2. (419 aa)
Kiaa0895Uncharacterized protein. (292 aa)
PLCB31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1255 aa)
LIPCLipase C, hepatic type. (463 aa)
PLA2G4APhospholipase A2. (750 aa)
PLA2G6Phospholipase A2 group VI. (807 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
Server load: low (18%) [HD]