(7 nodes) Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen network (Ictidomys tridecemlineatus)

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Your Input:
	LOC101977410	Uncharacterized protein; Belongs to the cytochrome P450 family. (508 aa)
	LOC101978636	Uncharacterized protein; Belongs to the cytochrome P450 family. (525 aa)
	LOC101955536	Uncharacterized protein. (346 aa)
	CYP2U1	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family. (546 aa)
	LOC101968373	Uncharacterized protein; Belongs to the cytochrome P450 family. (514 aa)
	CYP27A1	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (534 aa)
	CYP11A1	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...] (519 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CYP11A1	CYP27A1	ENSSTOP00000006311	ENSSTOP00000005904	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.704
CYP11A1	LOC101955536	ENSSTOP00000006311	ENSSTOP00000023732	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein.	0.737
CYP11A1	LOC101977410	ENSSTOP00000006311	ENSSTOP00000012140	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.581
CYP11A1	LOC101978636	ENSSTOP00000006311	ENSSTOP00000014247	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.585
CYP27A1	CYP11A1	ENSSTOP00000005904	ENSSTOP00000006311	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.704
CYP27A1	CYP2U1	ENSSTOP00000005904	ENSSTOP00000028667	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	0.414
CYP27A1	LOC101955536	ENSSTOP00000005904	ENSSTOP00000023732	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.612
CYP27A1	LOC101968373	ENSSTOP00000005904	ENSSTOP00000001317	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.715
CYP27A1	LOC101977410	ENSSTOP00000005904	ENSSTOP00000012140	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.609
CYP27A1	LOC101978636	ENSSTOP00000005904	ENSSTOP00000014247	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.609
CYP2U1	CYP27A1	ENSSTOP00000028667	ENSSTOP00000005904	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.414
CYP2U1	LOC101955536	ENSSTOP00000028667	ENSSTOP00000023732	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.836
CYP2U1	LOC101977410	ENSSTOP00000028667	ENSSTOP00000012140	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.835
CYP2U1	LOC101978636	ENSSTOP00000028667	ENSSTOP00000014247	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.836
LOC101955536	CYP11A1	ENSSTOP00000023732	ENSSTOP00000006311	Uncharacterized protein.	Cholesterol side-chain cleavage enzyme, mitochondrial; A cytochrome P450 monooxygenase that catalyzes the side-chain hydroxylation and cleavage of cholesterol to pregnenolone, the precursor of most steroid hormones. Catalyzes three sequential oxidation reactions of cholesterol, namely the hydroxylation at C22 followed with the hydroxylation at C20 to yield 20R,22R- hydroxycholesterol that is further cleaved between C20 and C22 to yield the C21-steroid pregnenolone and 4-methylpentanal. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate and reducing the se [...]	0.737
LOC101955536	CYP27A1	ENSSTOP00000023732	ENSSTOP00000005904	Uncharacterized protein.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.612
LOC101955536	CYP2U1	ENSSTOP00000023732	ENSSTOP00000028667	Uncharacterized protein.	Cytochrome P450 family 2 subfamily U member 1; Belongs to the cytochrome P450 family.	0.836
LOC101955536	LOC101968373	ENSSTOP00000023732	ENSSTOP00000001317	Uncharacterized protein.	Uncharacterized protein; Belongs to the cytochrome P450 family.	0.750
LOC101968373	CYP27A1	ENSSTOP00000001317	ENSSTOP00000005904	Uncharacterized protein; Belongs to the cytochrome P450 family.	Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family.	0.715
LOC101968373	LOC101955536	ENSSTOP00000001317	ENSSTOP00000023732	Uncharacterized protein; Belongs to the cytochrome P450 family.	Uncharacterized protein.	0.750