18 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	APOC3	Apolipoprotein C3. (130 aa)
	PNPLA3	Patatin like phospholipase domain containing 3. (420 aa)
	CPS1	Carbamoyl-phosphate synthase 1. (1500 aa)
	LPL	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans. (473 aa)
	PNLIPRP2	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family. (481 aa)
	LIPH	Lipase H. (444 aa)
	LIPC	Lipase C, hepatic type. (463 aa)
	PNPLA2	Patatin like phospholipase domain containing 2. (489 aa)
	LIPI	Lipase I. (415 aa)
	APOB	Apolipoprotein B. (4482 aa)
	MGLL	Monoglyceride lipase. (311 aa)
	Lipe	Hormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production. (763 aa)
	PNPLA5	Patatin like phospholipase domain containing 5. (389 aa)
	APOA5	Apolipoprotein A5. (370 aa)
	PNPLA4	Patatin like phospholipase domain containing 4. (253 aa)
	LIPG	Lipase G, endothelial type. (500 aa)
	DDHD2	DDHD domain containing 2. (701 aa)
	PNPLA1	Patatin like phospholipase domain containing 1. (515 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APOA5	APOB	ENSSTOP00000017348	ENSSTOP00000020666	Apolipoprotein A5.	Apolipoprotein B.	0.852
APOA5	APOC3	ENSSTOP00000017348	ENSSTOP00000022848	Apolipoprotein A5.	Apolipoprotein C3.	0.888
APOA5	LIPC	ENSSTOP00000017348	ENSSTOP00000030828	Apolipoprotein A5.	Lipase C, hepatic type.	0.819
APOA5	LPL	ENSSTOP00000017348	ENSSTOP00000001322	Apolipoprotein A5.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.639
APOB	APOA5	ENSSTOP00000020666	ENSSTOP00000017348	Apolipoprotein B.	Apolipoprotein A5.	0.852
APOB	APOC3	ENSSTOP00000020666	ENSSTOP00000022848	Apolipoprotein B.	Apolipoprotein C3.	0.973
APOB	LIPC	ENSSTOP00000020666	ENSSTOP00000030828	Apolipoprotein B.	Lipase C, hepatic type.	0.943
APOB	LPL	ENSSTOP00000020666	ENSSTOP00000001322	Apolipoprotein B.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.506
APOB	Lipe	ENSSTOP00000020666	ENSSTOP00000010392	Apolipoprotein B.	Hormone-sensitive lipase; In adipose tissue and heart, it primarily hydrolyzes stored triglycerides to free fatty acids, while in steroidogenic tissues, it principally converts cholesteryl esters to free cholesterol for steroid hormone production.	0.449
APOC3	APOA5	ENSSTOP00000022848	ENSSTOP00000017348	Apolipoprotein C3.	Apolipoprotein A5.	0.888
APOC3	APOB	ENSSTOP00000022848	ENSSTOP00000020666	Apolipoprotein C3.	Apolipoprotein B.	0.973
APOC3	LIPC	ENSSTOP00000022848	ENSSTOP00000030828	Apolipoprotein C3.	Lipase C, hepatic type.	0.635
DDHD2	LIPC	ENSSTOP00000024682	ENSSTOP00000030828	DDHD domain containing 2.	Lipase C, hepatic type.	0.607
DDHD2	PNLIPRP2	ENSSTOP00000024682	ENSSTOP00000007959	DDHD domain containing 2.	Triacylglycerol lipase; Belongs to the AB hydrolase superfamily. Lipase family.	0.498
LIPC	APOA5	ENSSTOP00000030828	ENSSTOP00000017348	Lipase C, hepatic type.	Apolipoprotein A5.	0.819
LIPC	APOB	ENSSTOP00000030828	ENSSTOP00000020666	Lipase C, hepatic type.	Apolipoprotein B.	0.943
LIPC	APOC3	ENSSTOP00000030828	ENSSTOP00000022848	Lipase C, hepatic type.	Apolipoprotein C3.	0.635
LIPC	DDHD2	ENSSTOP00000030828	ENSSTOP00000024682	Lipase C, hepatic type.	DDHD domain containing 2.	0.607
LIPC	LIPG	ENSSTOP00000030828	ENSSTOP00000014330	Lipase C, hepatic type.	Lipase G, endothelial type.	0.841
LIPC	LPL	ENSSTOP00000030828	ENSSTOP00000001322	Lipase C, hepatic type.	Lipoprotein lipase; Key enzyme in triglyceride metabolism. Catalyzes the hydrolysis of triglycerides from circulating chylomicrons and very low density lipoproteins (VLDL), and thereby plays an important role in lipid clearance from the blood stream, lipid utilization and storage. Mediates margination of triglyceride-rich lipoprotein particles in capillaries. Recruited to its site of action on the luminal surface of vascular endothelium by binding to GPIHBP1 and cell surface heparan sulfate proteoglycans.	0.924