STRINGSTRING
SH2B3 SH2B3 GRIP2 GRIP2 LRRK2 LRRK2 FRS2 FRS2 GNB2 GNB2 NUP62 NUP62 SPATA2 SPATA2 SAV1 SAV1 SHANK3 SHANK3 PTPN11 PTPN11 LDLRAP1 LDLRAP1 GNB5 GNB5 BLNK BLNK GNB3 GNB3 GRB2 GRB2 AXIN1 AXIN1 TRADD TRADD GNB1 GNB1 HOMER2 HOMER2 RGS14 RGS14 SH2B1 SH2B1 FRS3 FRS3 POC1B POC1B GNB4 GNB4 MAPK8IP3 MAPK8IP3 GAB2 GAB2 DOK3 DOK3 MAGI2 MAGI2 DOK1 DOK1 GRIP1 GRIP1 SPAG9 SPAG9 DOK2 DOK2 TRAT1 TRAT1 SORBS1 SORBS1 SHANK2 SHANK2 STAP1 STAP1 GRB10 GRB10 CRK CRK POC1A POC1A SH2B2 SH2B2 LAT LAT SHANK1 SHANK1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SH2B3SH2B adaptor protein 3. (429 aa)
GRIP2Glutamate receptor interacting protein 2. (949 aa)
LRRK2Leucine rich repeat kinase 2. (2520 aa)
FRS2Fibroblast growth factor receptor substrate 2. (508 aa)
GNB2G protein subunit beta 2. (371 aa)
NUP62Nucleoporin 62. (520 aa)
SPATA2Spermatogenesis associated 2. (509 aa)
SAV1Salvador family WW domain containing protein 1. (335 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1645 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
LDLRAP1Low density lipoprotein receptor adaptor protein 1. (308 aa)
GNB5G protein subunit beta 5. (386 aa)
BLNKB cell linker. (456 aa)
GNB3G protein subunit beta 3. (340 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
AXIN1Axin 1. (869 aa)
TRADDTNFRSF1A associated via death domain. (302 aa)
GNB1G protein subunit beta 1. (340 aa)
HOMER2Homer scaffold protein 2. (354 aa)
RGS14Regulator of G protein signaling 14. (568 aa)
SH2B1SH2B adaptor protein 1. (757 aa)
FRS3Fibroblast growth factor receptor substrate 3. (491 aa)
POC1BPOC1 centriolar protein B. (473 aa)
GNB4G protein subunit beta 4. (340 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1337 aa)
GAB2GRB2 associated binding protein 2. (638 aa)
DOK3Docking protein 3. (443 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1188 aa)
DOK1Docking protein 1. (496 aa)
GRIP1Glutamate receptor interacting protein 1. (1128 aa)
SPAG9Sperm associated antigen 9. (1329 aa)
DOK2Docking protein 2. (404 aa)
TRAT1T cell receptor associated transmembrane adaptor 1. (186 aa)
SORBS1Sorbin and SH3 domain containing 1. (931 aa)
SHANK2SH3 and multiple ankyrin repeat domains 2. (1572 aa)
STAP1Signal transducing adaptor family member 1. (297 aa)
GRB10Growth factor receptor bound protein 10. (576 aa)
CRKCRK proto-oncogene, adaptor protein. (305 aa)
POC1APOC1 centriolar protein A. (407 aa)
SH2B2SH2B adaptor protein 2. (636 aa)
LATLinker for activation of T cells. (234 aa)
SHANK1SH3 and multiple ankyrin repeat domains 1. (1514 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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