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HYAL1 HYAL1 B3GNT7 B3GNT7 NDST1 NDST1 ITIH1 ITIH1 ITIH3 ITIH3 Hs2st1 Hs2st1 NDST3 NDST3 CSGALNACT2 CSGALNACT2 UGDH UGDH IL1B IL1B Ndst2 Ndst2 HYAL4 HYAL4 SPAM1 SPAM1 B3GAT3 B3GAT3 HS3ST2 HS3ST2 EXT2 EXT2 PGLYRP3 PGLYRP3 B4GALNT3 B4GALNT3 SGSH SGSH HS3ST1 HS3ST1 SPOCK2 SPOCK2 LYG2 LYG2 XYLT1 XYLT1 HEXB HEXB HPSE HPSE ANGPT1 ANGPT1 BGN BGN CHST11 CHST11 XYLT2 XYLT2 DCN DCN CHSY1 CHSY1 EDNRB EDNRB MAMDC2 MAMDC2 HAS1 HAS1 CHPF2 CHPF2 HS3ST3B1 HS3ST3B1 TGFB1 TGFB1 Ids Ids CHPF CHPF LYVE1 LYVE1 Dse Dse GNS GNS NDST4 NDST4 LYG1 LYG1 HAS2 HAS2 CLN6 CLN6 EXT1 EXT1 ITIH2 ITIH2 TNFAIP6 TNFAIP6 ITIH5 ITIH5 ARSK ARSK HAS3 HAS3 Fgf2 Fgf2 LOC101976844 LOC101976844 HS3ST3A1 HS3ST3A1 B4GALT4 B4GALT4 CHST7 CHST7 ITIH6 ITIH6 CSGALNACT1 CSGALNACT1 B3GALT6 B3GALT6 LOC101965676 LOC101965676 PGLYRP1 PGLYRP1 CHST3 CHST3 IMPAD1 IMPAD1 B4GALT7 B4GALT7 CHSY3 CHSY3 NDNF NDNF CHST12 CHST12 CHST1 CHST1 PGLYRP2 PGLYRP2 PXYLP1 PXYLP1 EDNRA EDNRA GLCE GLCE B4GALNT4 B4GALNT4 CEMIP CEMIP PDGFRB PDGFRB CCND3 CCND3 CHST14 CHST14 SLC10A7 SLC10A7 HYAL3 HYAL3 IDUA IDUA HYAL2 HYAL2 ENSSTOP00000027992 ENSSTOP00000027992 SPOCK3 SPOCK3 ITIH4 ITIH4 PGLYRP4 PGLYRP4 SLC35D1 SLC35D1 CEMIP2 CEMIP2 EGFLAM EGFLAM Hexa Hexa
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
HYAL1Hyaluronidase. (449 aa)
B3GNT7Hexosyltransferase. (444 aa)
NDST1N-deacetylase and N-sulfotransferase 1. (882 aa)
ITIH1Inter-alpha-trypsin inhibitor heavy chain 1. (900 aa)
ITIH3Inter-alpha-trypsin inhibitor heavy chain 3. (889 aa)
Hs2st1Uncharacterized protein. (356 aa)
NDST3N-deacetylase and N-sulfotransferase 3. (873 aa)
CSGALNACT2Hexosyltransferase. (557 aa)
UGDHUDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family. (494 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa)
Ndst2Uncharacterized protein. (883 aa)
HYAL4Hyaluronidase. (481 aa)
SPAM1Hyaluronidase. (522 aa)
B3GAT3Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase; Belongs to the glycosyltransferase 43 family. (335 aa)
HS3ST2Sulfotransferase; Belongs to the sulfotransferase 1 family. (367 aa)
EXT2Exostosin glycosyltransferase 2; Belongs to the glycosyltransferase 47 family. (718 aa)
PGLYRP3Peptidoglycan recognition protein 3. (346 aa)
B4GALNT3Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (987 aa)
SGSHN-sulfoglucosamine sulfohydrolase. (502 aa)
HS3ST1Sulfotransferase; Belongs to the sulfotransferase 1 family. (311 aa)
SPOCK2SPARC (osteonectin), cwcv and kazal like domains proteoglycan 2. (423 aa)
LYG2Lysozyme g-like protein; Belongs to the glycosyl hydrolase 23 family. (212 aa)
XYLT1Xylosyltransferase 1. (840 aa)
HEXBBeta-hexosaminidase. (538 aa)
HPSEHeparanase. (539 aa)
ANGPT1Angiopoietin 1. (497 aa)
BGNBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (369 aa)
CHST11Carbohydrate sulfotransferase. (357 aa)
XYLT2Xylosyltransferase 2. (864 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
CHSY1Hexosyltransferase. (805 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
MAMDC2MAM domain containing 2. (686 aa)
HAS1Hyaluronan synthase 1. (539 aa)
CHPF2Hexosyltransferase. (772 aa)
HS3ST3B1Sulfotransferase; Belongs to the sulfotransferase 1 family. (390 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
IdsSulfatase domain-containing protein. (551 aa)
CHPFHexosyltransferase. (774 aa)
LYVE1Lymphatic vessel endothelial hyaluronan receptor 1. (318 aa)
DseDermatan sulfate epimerase. (821 aa)
GNSN-acetylglucosamine-6-sulfatase; Belongs to the sulfatase family. (552 aa)
NDST4N-deacetylase and N-sulfotransferase 4. (872 aa)
LYG1Lysozyme g-like protein; Belongs to the glycosyl hydrolase 23 family. (186 aa)
HAS2Hyaluronan synthase 2. (552 aa)
CLN6CLN6 transmembrane ER protein. (312 aa)
EXT1Exostosin glycosyltransferase 1; Belongs to the glycosyltransferase 47 family. (746 aa)
ITIH2Inter-alpha-trypsin inhibitor heavy chain 2. (912 aa)
TNFAIP6TNF alpha induced protein 6. (276 aa)
ITIH5Inter-alpha-trypsin inhibitor heavy chain 5. (944 aa)
ARSKArylsulfatase family member K. (538 aa)
HAS3Hyaluronan synthase 3. (553 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (144 aa)
LOC101976844Hyaluronidase. (485 aa)
HS3ST3A1Sulfotransferase; Belongs to the sulfotransferase 1 family. (348 aa)
B4GALT4Beta-1,4-galactosyltransferase 4. (343 aa)
CHST7Sulfotransferase; Belongs to the sulfotransferase 1 family. (485 aa)
ITIH6Inter-alpha-trypsin inhibitor heavy chain family member 6. (1298 aa)
CSGALNACT1Hexosyltransferase. (532 aa)
B3GALT6Hexosyltransferase. (323 aa)
LOC101965676Peptidase S1 domain-containing protein; Belongs to the peptidase S1 family. (283 aa)
PGLYRP1Peptidoglycan-recognition protein; Pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria. May kill Gram-positive bacteria by interfering with peptidoglycan biosynthesis. Involved in innate immunity. (195 aa)
CHST3Sulfotransferase; Belongs to the sulfotransferase 1 family. (473 aa)
IMPAD1Inositol monophosphatase domain containing 1. (329 aa)
B4GALT7Beta-1,4-galactosyltransferase 7. (327 aa)
CHSY3Hexosyltransferase. (884 aa)
NDNFNeuron derived neurotrophic factor. (568 aa)
CHST12Carbohydrate sulfotransferase. (418 aa)
CHST1Sulfotransferase; Belongs to the sulfotransferase 1 family. (411 aa)
PGLYRP2Peptidoglycan recognition protein 2. (522 aa)
PXYLP12-phosphoxylose phosphatase 1; Belongs to the histidine acid phosphatase family. (480 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
GLCEGlucuronic acid epimerase. (618 aa)
B4GALNT4Beta-1,4-N-acetylgalactosaminyltransferase; Transfers N-acetylgalactosamine (GalNAc) from UDP-GalNAc to N-acetylglucosamine-beta-benzyl with a beta-1,4-linkage to form N,N'- diacetyllactosediamine, GalNAc-beta-1,4-GlcNAc structures in N-linked glycans and probably O-linked glycans. (1099 aa)
CEMIPCell migration inducing hyaluronidase 1. (1365 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1112 aa)
CCND3Cyclin D3; Belongs to the cyclin family. (292 aa)
CHST14Carbohydrate sulfotransferase. (351 aa)
SLC10A7Sodium/bile acid cotransporter; Does not show transport activity towards bile acids or steroid sulfates; Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. (340 aa)
HYAL3Hyaluronidase. (415 aa)
IDUAIduronidase alpha-L-. (639 aa)
HYAL2Hyaluronidase. (472 aa)
ENSSTOP00000027992Sulfotransferase; Belongs to the sulfotransferase 1 family. (209 aa)
SPOCK3SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (397 aa)
ITIH4Inter-alpha-trypsin inhibitor heavy chain 4. (918 aa)
PGLYRP4Peptidoglycan recognition protein 4. (295 aa)
SLC35D1Solute carrier family 35 member D1. (280 aa)
CEMIP2Cell migration inducing hyaluronidase 2. (1383 aa)
EGFLAMEGF like, fibronectin type III and laminin G domains. (1023 aa)
HexaBeta-hexosaminidase. (527 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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