STRINGSTRING
MTM1 MTM1 FA2H FA2H PLPPR2 PLPPR2 DGKH DGKH CERKL CERKL ABCD4 ABCD4 PLA2G7 PLA2G7 SESN2 SESN2 PLPPR5 PLPPR5 MTMR7 MTMR7 DECR1 DECR1 GBA GBA MTMR10 MTMR10 GCDH GCDH MTMR12 MTMR12 ALDH1L2 ALDH1L2 MBOAT1 MBOAT1 ABCD1 ABCD1 B4GALNT2 B4GALNT2 ACADSB ACADSB PLPP4 PLPP4 ST3GAL2 ST3GAL2 ADH7 ADH7 MTMR11 MTMR11 CYGB CYGB LOC101973579 LOC101973579 ALOX12 ALOX12 ACOX2 ACOX2 ETFB ETFB ADH5 ADH5 ETFA ETFA PEX13 PEX13 ACAT2 ACAT2 HSD17B10 HSD17B10 LOC101962071 LOC101962071 GBA2 GBA2 MTMR6 MTMR6 INPP5F INPP5F INPP5K INPP5K ETFDH ETFDH SLC25A17 SLC25A17 ACAT1 ACAT1 ECI2 ECI2 HAO2 HAO2 PIK3C2B PIK3C2B CROT CROT HAO1 HAO1 ALOX15B ALOX15B INPP5J INPP5J CYP24A1 CYP24A1 INPP5B INPP5B HADHB HADHB HADH HADH DGKI DGKI PLPP5 PLPP5 B4GALNT1 B4GALNT1 PORCN PORCN PLPPR4 PLPPR4 CYP2E1 CYP2E1 LPCAT3 LPCAT3 LCAT LCAT A3GALT2 A3GALT2 CYP4V2 CYP4V2 ECHDC1 ECHDC1 I3MWA1_ICTTR I3MWA1_ICTTR ACADL ACADL PLPP2 PLPP2 SCP2 SCP2 I3MY97_ICTTR I3MY97_ICTTR SLC35C1 SLC35C1 LOC101958718 LOC101958718 LOC101967023 LOC101967023 ACADS ACADS MTMR8 MTMR8 FIG4 FIG4 ACAA2 ACAA2 ALOX15 ALOX15 EHHADH EHHADH PLPPR3 PLPPR3 ACAD11 ACAD11 AGK AGK ST3GAL4 ST3GAL4 HADHA HADHA ALOX12B ALOX12B SPHK1 SPHK1 CERK CERK Plpp3 Plpp3 MTMR9 MTMR9 MBOAT7 MBOAT7 MAPK14 MAPK14 PPARD PPARD PEX2 PEX2 PRKAA1 PRKAA1 ADH4 ADH4 AUH AUH ENSSTOP00000024432 ENSSTOP00000024432 Smim24 Smim24 PSORS1C2 PSORS1C2 Ech1 Ech1 PLPP1 PLPP1 CPT1C CPT1C LOC101963157 LOC101963157 INPP4B INPP4B ABCD3 ABCD3 GBGT1 GBGT1 DGKG DGKG PEX5 PEX5 ENSSTOP00000026931 ENSSTOP00000026931 ACADVL ACADVL ENSSTOP00000027857 ENSSTOP00000027857 CRAT CRAT ENSSTOP00000027890 ENSSTOP00000027890 ECHDC2 ECHDC2 RNF213 RNF213 MBOAT2 MBOAT2 MTMR4 MTMR4 PIP4P2 PIP4P2 HACL1 HACL1 DGKB DGKB MTMR2 MTMR2 ENSSTOP00000030369 ENSSTOP00000030369 ACAD10 ACAD10 PIP4P1 PIP4P1 PEX7 PEX7 DGKA DGKA MTMR3 MTMR3 DGKZ DGKZ STARD4 STARD4 INPP5A INPP5A ACOX1 ACOX1 Sacm1l Sacm1l B3GALT1 B3GALT1 ADIPOR1 ADIPOR1 MTMR1 MTMR1 SYNJ1 SYNJ1 CCDC180 CCDC180 ADIPOQ ADIPOQ OCRL OCRL SGPP2 SGPP2 ACOX3 ACOX3 CPT2 CPT2 SYNJ2 SYNJ2 LEP LEP PLPP6 PLPP6 GLT6D1 GLT6D1 SLC27A2 SLC27A2 PTEN PTEN DGKQ DGKQ IVD IVD LOC101974037 LOC101974037 ECHS1 ECHS1 CPT1B CPT1B Inpp5e Inpp5e CYP1A1 CYP1A1 HSD17B4 HSD17B4 LOC101972042 LOC101972042 BDH2 BDH2 ECI1 ECI1 I3MKI0_ICTTR I3MKI0_ICTTR CPT1A CPT1A PPARG PPARG ABCD2 ABCD2 SPHK2 SPHK2 SOAT1 SOAT1 ILVBL ILVBL MBOAT4 MBOAT4 DGKD DGKD INPP5D INPP5D LOC101958596 LOC101958596 SGPP1 SGPP1 SOAT2 SOAT2 INPPL1 INPPL1 EPHX2 EPHX2 TMEM130 TMEM130
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MTM1Myotubularin 1. (603 aa)
FA2HFatty acid 2-hydroxylase; Catalyzes stereospecific hydroxylation of free fatty acids at the C-2 position to produce (R)-2-hydroxy fatty acids, which are building blocks of sphingolipids and glycosphingolipids common in neural tissue and epidermis. Plays an essential role in the synthesis of galactosphingolipids of the myelin sheath. Responsible for the synthesis of sphingolipids and glycosphingolipids involved in the formation of epidermal lamellar bodies critical for skin permeability barrier. Participates in the synthesis of glycosphingolipids and a fraction of type II wax diesters i [...] (372 aa)
PLPPR2Phospholipid phosphatase related 2. (452 aa)
DGKHDiacylglycerol kinase. (1216 aa)
CERKLCeramide kinase like. (540 aa)
ABCD4ATP binding cassette subfamily D member 4. (593 aa)
PLA2G7Platelet-activating factor acetylhydrolase. (443 aa)
SESN2Sestrin 2. (479 aa)
PLPPR5Phospholipid phosphatase related 5. (321 aa)
MTMR7Myotubularin related protein 7. (661 aa)
DECR12,4-dienoyl-CoA reductase 1. (335 aa)
GBAGlucosylceramidase. (516 aa)
MTMR10Myotubularin related protein 10. (769 aa)
GCDHGlutaryl-CoA dehydrogenase. (438 aa)
MTMR12Myotubularin related protein 12. (747 aa)
ALDH1L210-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (923 aa)
MBOAT1Membrane bound O-acyltransferase domain containing 1; Belongs to the membrane-bound acyltransferase family. (417 aa)
ABCD1ATP binding cassette subfamily D member 1. (739 aa)
B4GALNT2Beta-1,4-N-acetyl-galactosaminyltransferase 2. (471 aa)
ACADSBAcyl-CoA dehydrogenase short/branched chain. (445 aa)
PLPP4Phospholipid phosphatase 4. (271 aa)
ST3GAL2ST3 beta-galactoside alpha-2,3-sialyltransferase 2; Belongs to the glycosyltransferase 29 family. (350 aa)
ADH7Alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide. (374 aa)
MTMR11Myotubularin related protein 11. (687 aa)
CYGBCytoglobin; Belongs to the globin family. (190 aa)
LOC101973579Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
ALOX12Arachidonate 12-lipoxygenase, 12S type. (664 aa)
ACOX2Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (681 aa)
ETFBElectron transfer flavoprotein subunit beta. (249 aa)
ADH5S-(hydroxymethyl)glutathione dehydrogenase; Belongs to the zinc-containing alcohol dehydrogenase family. Class-III subfamily. (374 aa)
ETFAElectron transfer flavoprotein subunit alpha. (333 aa)
PEX13Peroxisomal biogenesis factor 13. (403 aa)
ACAT2Acetyl-CoA acetyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (341 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (261 aa)
LOC101962071Uncharacterized protein. (380 aa)
GBA2Non-lysosomal glucosylceramidase; Non-lysosomal glucosylceramidase that catalyzes the hydrolysis of glucosylceramide (GlcCer) to free glucose and ceramide. (919 aa)
MTMR6Myotubularin related protein 6. (621 aa)
INPP5FInositol polyphosphate-5-phosphatase F. (1110 aa)
INPP5KInositol polyphosphate-5-phosphatase K. (510 aa)
ETFDHElectron transfer flavoprotein-ubiquinone oxidoreductase; Accepts electrons from ETF and reduces ubiquinone. (617 aa)
SLC25A17Solute carrier family 25 member 17; Belongs to the mitochondrial carrier (TC 2.A.29) family. (307 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (427 aa)
ECI2Enoyl-CoA delta isomerase 2. (390 aa)
HAO2Hydroxyacid oxidase 2. (353 aa)
PIK3C2BPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1617 aa)
CROTCarnitine O-octanoyltransferase; Belongs to the carnitine/choline acetyltransferase family. (612 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
ALOX15BArachidonate 15-lipoxygenase type B. (678 aa)
INPP5JInositol polyphosphate-5-phosphatase J. (1002 aa)
CYP24A1Cytochrome P450 family 24 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa)
INPP5BInositol polyphosphate-5-phosphatase B. (994 aa)
HADHBHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta; Belongs to the thiolase-like superfamily. Thiolase family. (475 aa)
HADHHydroxyacyl-CoA dehydrogenase. (314 aa)
DGKIDiacylglycerol kinase. (960 aa)
PLPP5Phospholipid phosphatase 5. (263 aa)
B4GALNT1Beta-1,4 N-acetylgalactosaminyltransferase. (533 aa)
PORCNPorcupine O-acyltransferase; Belongs to the membrane-bound acyltransferase family. (461 aa)
PLPPR4Phospholipid phosphatase related 4. (763 aa)
CYP2E1Cytochrome P450 family 2 subfamily E member 1; Belongs to the cytochrome P450 family. (492 aa)
LPCAT3Lysophosphatidylcholine acyltransferase 3; Belongs to the membrane-bound acyltransferase family. (487 aa)
LCATLecithin-cholesterol acyltransferase. (440 aa)
A3GALT2Alpha 1,3-galactosyltransferase 2. (341 aa)
CYP4V2Cytochrome P450 family 4 subfamily V member 2; Belongs to the cytochrome P450 family. (521 aa)
ECHDC1Ethylmalonyl-CoA decarboxylase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (312 aa)
I3MWA1_ICTTRUncharacterized protein. (56 aa)
ACADLAcyl-CoA dehydrogenase long chain. (430 aa)
PLPP2Phospholipid phosphatase 2. (287 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (547 aa)
I3MY97_ICTTRUncharacterized protein. (155 aa)
SLC35C1Solute carrier family 35 member C1. (364 aa)
LOC101958718Myotubularin phosphatase domain-containing protein. (538 aa)
LOC101967023IPPc domain-containing protein. (573 aa)
ACADSAcyl-CoA dehydrogenase short chain. (412 aa)
MTMR8Myotubularin related protein 8. (716 aa)
FIG4FIG4 phosphoinositide 5-phosphatase. (907 aa)
ACAA2Acetyl-CoA acyltransferase 2; Belongs to the thiolase-like superfamily. Thiolase family. (387 aa)
ALOX15Arachidonate 15-lipoxygenase. (663 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase; Belongs to the enoyl-CoA hydratase/isomerase family. (723 aa)
PLPPR3Phospholipid phosphatase related 3. (722 aa)
ACAD11Acyl-CoA dehydrogenase family member 11. (780 aa)
AGKAcylglycerol kinase. (420 aa)
ST3GAL4ST3 beta-galactoside alpha-2,3-sialyltransferase 4; Belongs to the glycosyltransferase 29 family. (333 aa)
HADHAHydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha; Belongs to the enoyl-CoA hydratase/isomerase family. (791 aa)
ALOX12BArachidonate 12-lipoxygenase, 12R type. (701 aa)
SPHK1Sphingosine kinase 1. (385 aa)
CERKCeramide kinase. (461 aa)
Plpp3acidPPc domain-containing protein. (312 aa)
MTMR9Myotubularin related protein 9. (549 aa)
MBOAT7Membrane bound O-acyltransferase domain containing 7; Belongs to the membrane-bound acyltransferase family. (472 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
PEX2Peroxisomal biogenesis factor 2. (305 aa)
PRKAA1Non-specific serine/threonine protein kinase. (561 aa)
ADH4Alcohol dehydrogenase 4 (class II), pi polypeptide. (298 aa)
AUHAU RNA binding methylglutaconyl-CoA hydratase; Belongs to the enoyl-CoA hydratase/isomerase family. (267 aa)
ENSSTOP00000024432MCD domain-containing protein. (267 aa)
Smim24Small integral membrane protein 24. (116 aa)
PSORS1C2Psoriasis susceptibility 1 candidate 2. (134 aa)
Ech1Uncharacterized protein. (169 aa)
PLPP1Phospholipid phosphatase 1. (285 aa)
CPT1CCarnitine palmitoyltransferase 1C. (834 aa)
LOC101963157Uncharacterized protein. (662 aa)
INPP4BInositol polyphosphate-4-phosphatase type II B. (939 aa)
ABCD3ATP binding cassette subfamily D member 3. (659 aa)
GBGT1Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 (FORS blood group). (347 aa)
DGKGDiacylglycerol kinase. (791 aa)
PEX5Peroxisomal biogenesis factor 5. (640 aa)
ENSSTOP00000026931SAC domain-containing protein. (246 aa)
ACADVLAcyl-CoA dehydrogenase very long chain. (655 aa)
ENSSTOP00000027857Uncharacterized protein. (73 aa)
CRATCarnitine O-acetyltransferase; Belongs to the carnitine/choline acetyltransferase family. (626 aa)
ENSSTOP00000027890annotation not available (246 aa)
ECHDC2Enoyl-CoA hydratase domain containing 2; Belongs to the enoyl-CoA hydratase/isomerase family. (294 aa)
RNF213Ring finger protein 213. (4892 aa)
MBOAT2Membrane bound O-acyltransferase domain containing 2; Belongs to the membrane-bound acyltransferase family. (495 aa)
MTMR4Myotubularin related protein 4. (1208 aa)
PIP4P2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (257 aa)
HACL12-hydroxyacyl-CoA lyase 1; Belongs to the TPP enzyme family. (499 aa)
DGKBDiacylglycerol kinase. (802 aa)
MTMR2Myotubularin related protein 2. (643 aa)
ENSSTOP00000030369Uncharacterized protein. (353 aa)
ACAD10Acyl-CoA dehydrogenase family member 10. (1072 aa)
PIP4P1Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (277 aa)
PEX7Peroxisomal biogenesis factor 7. (318 aa)
DGKADiacylglycerol kinase. (799 aa)
MTMR3Myotubularin related protein 3. (1006 aa)
DGKZDiacylglycerol kinase. (1154 aa)
STARD4StAR related lipid transfer domain containing 4. (222 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (387 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
Sacm1lSAC domain-containing protein. (587 aa)
B3GALT1Hexosyltransferase. (326 aa)
ADIPOR1Uncharacterized protein. (375 aa)
MTMR1Myotubularin related protein 1. (665 aa)
SYNJ1Synaptojanin 1. (1609 aa)
CCDC180Coiled-coil domain containing 180. (1589 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (244 aa)
OCRLOCRL inositol polyphosphate-5-phosphatase. (901 aa)
SGPP2Sphingosine-1-phosphate phosphatase 2. (399 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (700 aa)
CPT2Carnitine palmitoyltransferase 2; Belongs to the carnitine/choline acetyltransferase family. (645 aa)
SYNJ2Synaptojanin 2. (1471 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
PLPP6Phospholipid phosphatase 6. (294 aa)
GLT6D1Glycosyltransferase 6 domain containing 1. (291 aa)
SLC27A2Solute carrier family 27 member 2. (620 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
DGKQDiacylglycerol kinase. (924 aa)
IVDIsovaleryl-CoA dehydrogenase. (375 aa)
LOC101974037C1q domain-containing protein. (333 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
CPT1BCarnitine palmitoyltransferase 1B; Belongs to the carnitine/choline acetyltransferase family. (772 aa)
Inpp5eIPPc domain-containing protein. (438 aa)
CYP1A1Cytochrome P450 family 1 subfamily A member 1; Belongs to the cytochrome P450 family. (523 aa)
HSD17B4Hydroxysteroid 17-beta dehydrogenase 4. (736 aa)
LOC101972042Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (424 aa)
BDH23-hydroxybutyrate dehydrogenase 2. (245 aa)
ECI1Enoyl-CoA delta isomerase 1; Belongs to the enoyl-CoA hydratase/isomerase family. (243 aa)
I3MKI0_ICTTRUncharacterized protein; Belongs to the glycosyltransferase 29 family. (332 aa)
CPT1ACarnitine palmitoyltransferase 1A; Belongs to the carnitine/choline acetyltransferase family. (773 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
ABCD2ATP binding cassette subfamily D member 2. (741 aa)
SPHK2Sphingosine kinase 2. (655 aa)
SOAT1O-acyltransferase. (544 aa)
ILVBLIlvB acetolactate synthase like; Belongs to the TPP enzyme family. (632 aa)
MBOAT4Membrane bound O-acyltransferase domain containing 4; Belongs to the membrane-bound acyltransferase family. (435 aa)
DGKDDiacylglycerol kinase. (1170 aa)
INPP5DInositol polyphosphate-5-phosphatase D. (1213 aa)
LOC101958596Uncharacterized protein. (231 aa)
SGPP1Sphingosine-1-phosphate phosphatase 1. (428 aa)
SOAT2O-acyltransferase. (524 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1264 aa)
EPHX2Epoxide hydrolase 2. (555 aa)
TMEM130Transmembrane protein 130. (338 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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