STRINGSTRING
PIK3R1 PIK3R1 CD109 CD109 NF1 NF1 CTNNB1 CTNNB1 IAPP IAPP FARP2 FARP2 SFRP1 SFRP1 TYROBP TYROBP CCN4 CCN4 CSF1R CSF1R SNX10 SNX10 TNFRSF11A TNFRSF11A FAM20C FAM20C OCSTAMP OCSTAMP CSF1 CSF1 GPR183 GPR183 DCSTAMP DCSTAMP EFNA2 EFNA2 Foxp1 Foxp1 OSCAR OSCAR MAPK14 MAPK14 GPR68 GPR68 TNF TNF TCIRG1 TCIRG1 ATP6AP1 ATP6AP1 SH3PXD2A SH3PXD2A SBNO2 SBNO2 Anxa2 Anxa2 I3MIQ6_ICTTR I3MIQ6_ICTTR CALCR CALCR TREM2 TREM2 TNFSF11 TNFSF11 GPC3 GPC3 TGFB1 TGFB1 IREB2 IREB2 LRRK1 LRRK1 NFATC1 NFATC1 TRAF6 TRAF6 IL20 IL20 MITF MITF GLO1 GLO1 TFRC TFRC GAB2 GAB2 EPHA2 EPHA2 FOS FOS PAFAH1B1 PAFAH1B1 TMEM64 TMEM64 CD81 CD81 CHUK CHUK Tob2 Tob2 JUNB JUNB TCTA TCTA LOC101961139 LOC101961139
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (724 aa)
CD109CD109 molecule. (1235 aa)
NF1Neurofibromin 1. (2473 aa)
CTNNB1Catenin beta 1. (781 aa)
IAPPIslet amyloid polypeptide. (93 aa)
FARP2FERM, ARH/RhoGEF and pleckstrin domain protein 2. (1063 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
TYROBPTYRO protein tyrosine kinase binding protein. (113 aa)
CCN4Cellular communication network factor 4. (366 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (975 aa)
SNX10Sorting nexin 10. (201 aa)
TNFRSF11ATNF receptor superfamily member 11a. (625 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (580 aa)
OCSTAMPOsteoclast stimulatory transmembrane protein. (469 aa)
CSF1Colony stimulating factor 1. (497 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (357 aa)
DCSTAMPDendrocyte expressed seven transmembrane protein. (474 aa)
EFNA2Ephrin A2; Belongs to the ephrin family. (197 aa)
Foxp1Fork-head domain-containing protein. (674 aa)
OSCAROsteoclast associated Ig-like receptor. (277 aa)
MAPK14Mitogen-activated protein kinase. (360 aa)
GPR68G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (375 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (861 aa)
ATP6AP1ATPase H+ transporting accessory protein 1. (468 aa)
SH3PXD2ASH3 and PX domains 2A. (1106 aa)
SBNO2Strawberry notch homolog 2. (1382 aa)
Anxa2Annexin. (339 aa)
I3MIQ6_ICTTRUncharacterized protein. (168 aa)
CALCRCalcitonin receptor; Belongs to the G-protein coupled receptor 2 family. (497 aa)
TREM2Triggering receptor expressed on myeloid cells 2. (262 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (321 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
IREB2Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (963 aa)
LRRK1Leucine rich repeat kinase 1. (2014 aa)
NFATC1Nuclear factor of activated T cells 1. (941 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (530 aa)
IL20Interleukin 20. (176 aa)
MITFMelanocyte inducing transcription factor. (482 aa)
GLO1Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. (185 aa)
TFRCTransferrin receptor. (760 aa)
GAB2GRB2 associated binding protein 2. (638 aa)
EPHA2EPH receptor A2. (923 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (380 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)
TMEM64Transmembrane protein 64. (313 aa)
CD81Tetraspanin. (214 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (769 aa)
Tob2Uncharacterized protein. (345 aa)
JUNBJunB proto-oncogene, AP-1 transcription factor subunit. (347 aa)
TCTAT cell leukemia translocation altered. (133 aa)
LOC101961139Anti_prolifrtn domain-containing protein. (290 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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