STRINGSTRING
NKX6-2 NKX6-2 RYK RYK SEMA3G SEMA3G RTN4 RTN4 SEMA6C SEMA6C NTN1 NTN1 MEGF8 MEGF8 SEMA4D SEMA4D SEMA4F SEMA4F DRAXIN DRAXIN MAP1B MAP1B BMPR2 BMPR2 PAFAH1B1 PAFAH1B1 SEMA5A SEMA5A DBNL DBNL FN1 FN1 PLXNA3 PLXNA3 DIP2B DIP2B DPYSL2 DPYSL2 DSCAM DSCAM CXCL12 CXCL12 SEMA3D SEMA3D SEMA4C SEMA4C EIF2B2 EIF2B2 CDKL3 CDKL3 TRIM46 TRIM46 SEMA4G SEMA4G RPL4 RPL4 Mag Mag SEMA4B SEMA4B SEMA5B SEMA5B SEMA3E SEMA3E IFRD1 IFRD1 SLIT1 SLIT1 PLXNA4 PLXNA4 ACTR3 ACTR3 RAB21 RAB21 ZFYVE27 ZFYVE27 TRPV2 TRPV2 NKX6-1 NKX6-1 PAK1 PAK1 LIMK1 LIMK1 LRP1 LRP1 ATP5MC1 ATP5MC1 NRP1 NRP1 SRF SRF CDKL5 CDKL5 WDR36 WDR36 SEMA6D SEMA6D SEMA3F SEMA3F CNTF CNTF SIN3A SIN3A BARHL2 BARHL2 RNF6 RNF6 Myo5b Myo5b SEMA7A SEMA7A CDH4 CDH4 ADNP ADNP TTL TTL Ndel1 Ndel1 MAPT MAPT DNM2 DNM2 CCR5 CCR5 MAP2 MAP2 MGLL MGLL WNT3 WNT3 WNT5A WNT5A IFRD2 IFRD2 POU4F2 POU4F2 WNT3A WNT3A SEMA6B SEMA6B OLFM1 OLFM1 MT3 MT3 ISLR2 ISLR2 GSK3B GSK3B SHTN1 SHTN1 RTN4R RTN4R SEMA6A SEMA6A CYFIP1 CYFIP1 SEMA3B SEMA3B RUFY3 RUFY3 LOC101974646 LOC101974646 CTTN CTTN TRPC5 TRPC5 LOC101959679 LOC101959679 PTPRS PTPRS TNFRSF12A TNFRSF12A TNR TNR GOLGA4 GOLGA4 KIAA0319 KIAA0319 SEMA3C SEMA3C NTRK3 NTRK3 MAP3K13 MAP3K13 DBN1 DBN1 ENSSTOP00000028944 ENSSTOP00000028944 SEMA4A SEMA4A ENSSTOP00000030879 ENSSTOP00000030879 ARHGAP4 ARHGAP4 CDK5 CDK5 ANAPC2 ANAPC2 L1CAM L1CAM SLIT2 SLIT2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NKX6-2NK6 homeobox 2. (267 aa)
RYKReceptor like tyrosine kinase. (475 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (773 aa)
RTN4Reticulon. (1177 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (866 aa)
NTN1Netrin 1. (596 aa)
MEGF8Multiple EGF like domains 8. (2815 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (747 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (336 aa)
MAP1BMicrotubule associated protein 1B. (2469 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (411 aa)
SEMA5ASemaphorin 5A. (1074 aa)
DBNLDrebrin like. (433 aa)
FN1Fibronectin 1. (2474 aa)
PLXNA3Plexin A3. (1872 aa)
DIP2BDisco interacting protein 2 homolog B. (1576 aa)
DPYSL2Dihydropyrimidinase like 2. (677 aa)
DSCAMDS cell adhesion molecule. (2012 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (735 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (831 aa)
EIF2B2Eukaryotic translation initiation factor 2B subunit beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (351 aa)
CDKL3Cyclin dependent kinase like 3. (592 aa)
TRIM46Tripartite motif containing 46. (759 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (839 aa)
RPL4Ribosomal protein L4. (424 aa)
MagUncharacterized protein. (64 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (823 aa)
SEMA5BSemaphorin 5B. (1093 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (721 aa)
IFRD1Interferon related developmental regulator 1. (449 aa)
SLIT1Slit guidance ligand 1. (1525 aa)
PLXNA4Plexin A4. (1893 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
RAB21RAB21, member RAS oncogene family. (221 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (409 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (758 aa)
NKX6-1NK6 homeobox 1. (366 aa)
PAK1Non-specific serine/threonine protein kinase. (544 aa)
LIMK1LIM domain kinase 1. (628 aa)
LRP1LDL receptor related protein 1. (4508 aa)
ATP5MC1ATP synthase membrane subunit c locus 1; Belongs to the ATPase C chain family. (136 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
SRFSerum response factor. (505 aa)
CDKL5Cyclin dependent kinase like 5. (960 aa)
WDR36WD repeat domain 36. (1014 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1061 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
CNTFCiliary neurotrophic factor. (199 aa)
SIN3ASIN3 transcription regulator family member A. (1274 aa)
BARHL2BarH like homeobox 2. (388 aa)
RNF6Ring finger protein 6. (683 aa)
Myo5bUncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1814 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
CDH4Cadherin 4; Cadherins are calcium-dependent cell adhesion proteins. (864 aa)
ADNPActivity dependent neuroprotector homeobox. (1103 aa)
TTLTubulin tyrosine ligase. (384 aa)
Ndel1NUDE_C domain-containing protein. (345 aa)
MAPTMicrotubule-associated protein. (430 aa)
DNM2Dynamin 2; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (870 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (351 aa)
MAP2Microtubule-associated protein. (1878 aa)
MGLLMonoglyceride lipase. (311 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
IFRD2Interferon related developmental regulator 2. (440 aa)
POU4F2POU domain protein. (410 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (801 aa)
OLFM1Olfactomedin 1. (435 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
ISLR2Immunoglobulin superfamily containing leucine rich repeat 2. (789 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
SHTN1Shootin 1. (611 aa)
RTN4RReticulon 4 receptor. (473 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (778 aa)
RUFY3RUN and FYVE domain containing 3. (583 aa)
LOC101974646NUDE_C domain-containing protein. (376 aa)
CTTNCortactin. (549 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
LOC101959679Uncharacterized protein. (767 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1855 aa)
TNFRSF12ATNF receptor superfamily member 12A. (129 aa)
TNRTenascin R. (1358 aa)
GOLGA4Golgin A4. (2292 aa)
KIAA0319KIAA0319. (901 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
NTRK3Tyrosine-protein kinase receptor. (864 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
DBN1Drebrin 1. (679 aa)
ENSSTOP00000028944Uncharacterized protein. (169 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (758 aa)
ENSSTOP00000030879Uncharacterized protein. (105 aa)
ARHGAP4Rho GTPase activating protein 4. (940 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (830 aa)
L1CAML1 cell adhesion molecule. (1256 aa)
SLIT2Slit guidance ligand 2. (1559 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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