STRINGSTRING
WNT3A WNT3A KIAA0319 KIAA0319 IFRD2 IFRD2 WNT5A WNT5A SEMA6C SEMA6C NTN1 NTN1 SEMA4D SEMA4D SEMA4F SEMA4F DRAXIN DRAXIN SEMA5A SEMA5A PLXNA3 PLXNA3 DIP2B DIP2B SEMA3D SEMA3D SEMA4C SEMA4C CDKL3 CDKL3 TRIM46 TRIM46 SEMA3B SEMA3B PTPRS PTPRS TNR TNR SLIT2 SLIT2 CDK5 CDK5 ARHGAP4 ARHGAP4 SEMA4A SEMA4A SEMA3C SEMA3C WNT3 WNT3 MAP2 MAP2 CCR5 CCR5 SEMA7A SEMA7A RNF6 RNF6 SEMA3F SEMA3F SEMA6D SEMA6D NRP1 NRP1 ACTR3 ACTR3 SLIT1 SLIT1 IFRD1 IFRD1 SEMA3E SEMA3E SEMA5B SEMA5B SEMA4B SEMA4B SEMA4G SEMA4G Mag Mag RYK RYK SEMA3G SEMA3G RTN4 RTN4 SEMA6A SEMA6A RTN4R RTN4R MT3 MT3 SEMA6B SEMA6B
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
KIAA0319KIAA0319. (901 aa)
IFRD2Interferon related developmental regulator 2. (440 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (866 aa)
NTN1Netrin 1. (596 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (747 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (770 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (336 aa)
SEMA5ASemaphorin 5A. (1074 aa)
PLXNA3Plexin A3. (1872 aa)
DIP2BDisco interacting protein 2 homolog B. (1576 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (735 aa)
SEMA4CSemaphorin 4C; Belongs to the semaphorin family. (831 aa)
CDKL3Cyclin dependent kinase like 3. (592 aa)
TRIM46Tripartite motif containing 46. (759 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (778 aa)
PTPRSProtein tyrosine phosphatase receptor type S. (1855 aa)
TNRTenascin R. (1358 aa)
SLIT2Slit guidance ligand 2. (1559 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
ARHGAP4Rho GTPase activating protein 4. (940 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (758 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (751 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
MAP2Microtubule-associated protein. (1878 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (351 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (664 aa)
RNF6Ring finger protein 6. (683 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (785 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1061 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
SLIT1Slit guidance ligand 1. (1525 aa)
IFRD1Interferon related developmental regulator 1. (449 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (721 aa)
SEMA5BSemaphorin 5B. (1093 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (823 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (839 aa)
MagUncharacterized protein. (64 aa)
RYKReceptor like tyrosine kinase. (475 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (773 aa)
RTN4Reticulon. (1177 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
RTN4RReticulon 4 receptor. (473 aa)
MT3Metallothionein; Metallothioneins have a high content of cysteine residues that bind various heavy metals. (68 aa)
SEMA6BSemaphorin 6B; Belongs to the semaphorin family. (801 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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