17 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SNX27	Sorting nexin 27. (542 aa)
	Dctn1	CAP-Gly domain-containing protein. (1281 aa)
	DENND5A	DENN domain containing 5A. (1288 aa)
	VPS35	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting. (796 aa)
	SNX3	Sorting nexin 3. (162 aa)
	SNX5	Sorting nexin; Involved in several stages of intracellular trafficking. (394 aa)
	TBC1D5	TBC1 domain family member 5. (818 aa)
	DENND4C	DENN domain containing 4C. (1957 aa)
	SNX8	Sorting nexin 8. (455 aa)
	VPS26B	VPS26, retromer complex component B. (336 aa)
	RAB7A	RAB7A, member RAS oncogene family. (207 aa)
	TRIM27	Tripartite motif containing 27. (513 aa)
	VPS29	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. (186 aa)
	SNX2	Sorting nexin 2. (523 aa)
	SNX12	Sorting nexin 12. (163 aa)
	SNX1	Sorting nexin 1. (529 aa)
	VPS26A	VPS26, retromer complex component A. (327 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DENND4C	DENND5A	ENSSTOP00000019519	ENSSTOP00000002280	DENN domain containing 4C.	DENN domain containing 5A.	0.737
DENND4C	RAB7A	ENSSTOP00000019519	ENSSTOP00000022028	DENN domain containing 4C.	RAB7A, member RAS oncogene family.	0.610
DENND4C	VPS29	ENSSTOP00000019519	ENSSTOP00000024864	DENN domain containing 4C.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.406
DENND4C	VPS35	ENSSTOP00000019519	ENSSTOP00000003380	DENN domain containing 4C.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.409
DENND5A	DENND4C	ENSSTOP00000002280	ENSSTOP00000019519	DENN domain containing 5A.	DENN domain containing 4C.	0.737
DENND5A	RAB7A	ENSSTOP00000002280	ENSSTOP00000022028	DENN domain containing 5A.	RAB7A, member RAS oncogene family.	0.421
DENND5A	SNX1	ENSSTOP00000002280	ENSSTOP00000028729	DENN domain containing 5A.	Sorting nexin 1.	0.563
DENND5A	SNX2	ENSSTOP00000002280	ENSSTOP00000025309	DENN domain containing 5A.	Sorting nexin 2.	0.444
Dctn1	RAB7A	ENSSTOP00000000893	ENSSTOP00000022028	CAP-Gly domain-containing protein.	RAB7A, member RAS oncogene family.	0.671
Dctn1	SNX1	ENSSTOP00000000893	ENSSTOP00000028729	CAP-Gly domain-containing protein.	Sorting nexin 1.	0.564
Dctn1	SNX2	ENSSTOP00000000893	ENSSTOP00000025309	CAP-Gly domain-containing protein.	Sorting nexin 2.	0.514
Dctn1	SNX27	ENSSTOP00000000893	ENSSTOP00000031694	CAP-Gly domain-containing protein.	Sorting nexin 27.	0.478
Dctn1	SNX3	ENSSTOP00000000893	ENSSTOP00000006492	CAP-Gly domain-containing protein.	Sorting nexin 3.	0.478
Dctn1	SNX5	ENSSTOP00000000893	ENSSTOP00000013809	CAP-Gly domain-containing protein.	Sorting nexin; Involved in several stages of intracellular trafficking.	0.769
Dctn1	SNX8	ENSSTOP00000000893	ENSSTOP00000020020	CAP-Gly domain-containing protein.	Sorting nexin 8.	0.454
Dctn1	TRIM27	ENSSTOP00000000893	ENSSTOP00000024280	CAP-Gly domain-containing protein.	Tripartite motif containing 27.	0.434
Dctn1	VPS26A	ENSSTOP00000000893	ENSSTOP00000031317	CAP-Gly domain-containing protein.	VPS26, retromer complex component A.	0.535
Dctn1	VPS26B	ENSSTOP00000000893	ENSSTOP00000021610	CAP-Gly domain-containing protein.	VPS26, retromer complex component B.	0.491
Dctn1	VPS29	ENSSTOP00000000893	ENSSTOP00000024864	CAP-Gly domain-containing protein.	Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.	0.679
Dctn1	VPS35	ENSSTOP00000000893	ENSSTOP00000003380	CAP-Gly domain-containing protein.	Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.	0.528