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| | Hnrnpa1 | Uncharacterized protein. (374 aa) |
| | Ldha | L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (361 aa) |
| | SESN3 | Sestrin 3. (492 aa) |
| | NFE2L2 | Nuclear factor, erythroid 2 like 2. (600 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2520 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (325 aa) |
| | MAPK3 | Mitogen-activated protein kinase. (361 aa) |
| | PIK3R4 | Phosphoinositide-3-kinase regulatory subunit 4. (1305 aa) |
| | RALB | RAS like proto-oncogene B. (206 aa) |
| | NUDT15 | Nudix hydrolase 15. (171 aa) |
| | WIPI2 | WD repeat domain, phosphoinositide interacting 2. (445 aa) |
| | CLEC16A | C-type lectin domain containing 16A. (1050 aa) |
| | RASL10A | RAS like family 10 member A. (203 aa) |
| | EIF2S1 | Eukaryotic translation initiation factor 2 subunit alpha. (315 aa) |
| | SFRP2 | Secreted frizzled related protein 2. (295 aa) |
| | BMPR2 | Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1038 aa) |
| | LARS1 | Leucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (1176 aa) |
| | GCK | Phosphotransferase. (467 aa) |
| | NR4A2 | Nuclear receptor subfamily 4 group A member 2. (598 aa) |
| | FOS | Fos proto-oncogene, AP-1 transcription factor subunit. (380 aa) |
| | WIPI1 | WD repeat domain, phosphoinositide interacting 1. (422 aa) |
| | ERCC6 | ERCC excision repair 6, chromatin remodeling factor. (1521 aa) |
| | FBXO22 | F-box protein 22. (404 aa) |
| | FOSL1 | FOS like 1, AP-1 transcription factor subunit. (275 aa) |
| | FADS1 | Fatty acid desaturase 1. (445 aa) |
| | TSC1 | TSC complex subunit 1. (1164 aa) |
| | Sik1 | Uncharacterized protein. (776 aa) |
| | PRKD1 | Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (843 aa) |
| | WDR24 | WD repeat domain 24. (789 aa) |
| | Xbp1 | BZIP domain-containing protein. (351 aa) |
| | PIK3C2B | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1617 aa) |
| | NDOR1 | NADPH-dependent diflavin oxidoreductase 1; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Transfers electrons from NADPH to the Fe/S cluster of CIAPIN1. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. (597 aa) |
| | ADORA2B | Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa) |
| | C12orf66 | Chromosome 12 open reading frame 66. (445 aa) |
| | RRAGB | Ras related GTP binding B. (374 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (529 aa) |
| | CBL | Cbl proto-oncogene. (870 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (682 aa) |
| | UPP1 | Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (311 aa) |
| | HNRNPL | Heterogeneous nuclear ribonucleoprotein L. (588 aa) |
| | RICTOR | RPTOR independent companion of MTOR complex 2. (1660 aa) |
| | BRSK1 | BR serine/threonine kinase 1. (772 aa) |
| | MAP1LC3A | Microtubule associated protein 1 light chain 3 alpha. (121 aa) |
| | MMP9 | Matrix metallopeptidase 9. (667 aa) |
| | ITGA6 | Integrin subunit alpha 6; Belongs to the integrin alpha chain family. (1091 aa) |
| | PRKAG3 | Protein kinase AMP-activated non-catalytic subunit gamma 3. (490 aa) |
| | STK24 | Serine/threonine kinase 24. (432 aa) |
| | PHEX | Phosphate regulating endopeptidase homolog X-linked. (749 aa) |
| | PDIA3 | Protein disulfide-isomerase. (505 aa) |
| | KPTN | Kaptin, actin binding protein. (402 aa) |
| | AADACL3 | Arylacetamide deacetylase like 3. (407 aa) |
| | ATF3 | Activating transcription factor 3. (181 aa) |
| | RRAGD | Ras related GTP binding D. (399 aa) |
| | DAPL1 | Death associated protein like 1. (110 aa) |
| | CTSV | Cathepsin V; Belongs to the peptidase C1 family. (332 aa) |
| | SEH1L | SEH1 like nucleoporin; Belongs to the WD repeat SEC13 family. (323 aa) |
| | FGF23 | Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (252 aa) |
| | AIFM1 | Apoptosis inducing factor mitochondria associated 1. (613 aa) |
| | SLC34A1 | Solute carrier family 34 member 1. (639 aa) |
| | ASGR1 | Asialoglycoprotein receptor 1. (285 aa) |
| | PRKAB1 | Protein kinase AMP-activated non-catalytic subunit beta 1. (270 aa) |
| | GBA | Glucosylceramidase. (516 aa) |
| | MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1307 aa) |
| | PIK3C2A | Phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1641 aa) |
| | IREB2 | Iron responsive element binding protein 2; Belongs to the aconitase/IPM isomerase family. (963 aa) |
| | SESN2 | Sestrin 2. (479 aa) |
| | BMF | Bcl2 modifying factor. (258 aa) |
| | HIGD1A | HIG1 hypoxia inducible domain family member 1A. (93 aa) |
| | EIF2AK3 | Eukaryotic translation initiation factor 2 alpha kinase 3. (1005 aa) |
| | Foxo1 | Forkhead box protein O1; Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalc [...] (535 aa) |
| | P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (596 aa) |
| | CARTPT | CART prepropeptide. (129 aa) |
| | ITGA4 | Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1032 aa) |
| | DCPS | Decapping enzyme, scavenger. (335 aa) |
| | TTC5 | Tetratricopeptide repeat domain 5. (440 aa) |
| | PRKAA2 | Non-specific serine/threonine protein kinase. (552 aa) |
| | MAP1LC3C | Microtubule associated protein 1 light chain 3 gamma. (153 aa) |
| | DSC2 | Desmocollin 2; Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. (900 aa) |
| | UCP2 | Uncoupling protein 2; Belongs to the mitochondrial carrier (TC 2.A.29) family. (309 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | TBL2 | Transducin beta like 2. (443 aa) |
| | RRAGC | Ras related GTP binding C. (320 aa) |
| | BRIP1 | BRCA1 interacting protein C-terminal helicase 1. (937 aa) |
| | ZFYVE1 | Zinc finger FYVE-type containing 1. (777 aa) |
| | ULK1 | Unc-51 like autophagy activating kinase 1. (1041 aa) |
| | Hspa5 | Endoplasmic reticulum chaperone BiP; Endoplasmic reticulum chaperone that plays a key role in protein folding and quality control in the endoplasmic reticulum lumen (By similarity). Involved in the correct folding of proteins and degradation of misfolded proteins via its interaction with DNAJC10/ERdj5, probably to facilitate the release of DNAJC10/ERdj5 from its substrate (By similarity). Acts as a key repressor of the ERN1/IRE1-mediated unfolded protein response (UPR). In the unstressed endoplasmic reticulum, recruited by DNAJB9/ERdj4 to the luminal region of ERN1/IRE1, leading to dis [...] (654 aa) |
| | AQP2 | Aquaporin 2; Belongs to the MIP/aquaporin (TC 1.A.8) family. (271 aa) |
| | ARHGAP35 | Rho GTPase activating protein 35. (1500 aa) |
| | WNT2B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa) |
| | CHKA | Choline kinase alpha. (411 aa) |
| | MYOCD | Myocardin. (894 aa) |
| | DNM1L | Dynamin 1 like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (749 aa) |
| | FLCN | Folliculin. (579 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa) |
| | DNAJC15 | DnaJ heat shock protein family (Hsp40) member C15. (148 aa) |
| | PICK1 | Protein interacting with PRKCA 1. (416 aa) |
| | Srebf2 | BHLH domain-containing protein. (1136 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (783 aa) |
| | WRN | WRN RecQ like helicase. (1448 aa) |
| | EIF2AK2 | Eukaryotic translation initiation factor 2 alpha kinase 2. (538 aa) |
| | GCN1 | GCN1 activator of EIF2AK4. (2664 aa) |
| | ATF2 | Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa) |
| | SRF | Serum response factor. (505 aa) |
| | USP33 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (911 aa) |
| | GLUL | Glutamine synthetase. (373 aa) |
| | TNKS | Poly [ADP-ribose] polymerase. (1327 aa) |
| | MIOS | Meiosis regulator for oocyte development. (875 aa) |
| | PRKAG1 | Protein kinase AMP-activated non-catalytic subunit gamma 1. (330 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa) |
| | MAPK1 | Mitogen-activated protein kinase. (331 aa) |
| | PCK1 | Phosphoenolpyruvate carboxykinase 1. (622 aa) |
| | I3MNM5_ICTTR | Uncharacterized protein. (131 aa) |
| | FES | Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (822 aa) |
| | MYBBP1A | MYB binding protein 1a. (1318 aa) |
| | SLC39A4 | Solute carrier family 39 member 4. (615 aa) |
| | SUV39H1 | Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (412 aa) |
| | NUDT1 | Nudix hydrolase 1; Belongs to the Nudix hydrolase family. (156 aa) |
| | EIF2AK4 | Eukaryotic translation initiation factor 2 alpha kinase 4. (1631 aa) |
| | PAWR | Pro-apoptotic WT1 regulator. (340 aa) |
| | AQP3 | Aquaporin 3 (Gill blood group); Belongs to the MIP/aquaporin (TC 1.A.8) family. (292 aa) |
| | SLC39A5 | Solute carrier family 39 member 5. (538 aa) |
| | SLC38A3 | Solute carrier family 38 member 3. (504 aa) |
| | NPRL2 | NPR2 like, GATOR1 complex subunit. (380 aa) |
| | RRP8 | Ribosomal RNA-processing protein 8; Essential component of the eNoSC (energy-dependent nucleolar silencing) complex, a complex that mediates silencing of rDNA in response to intracellular energy status and acts by recruiting histone- modifying enzymes. The eNoSC complex is able to sense the energy status of cell: upon glucose starvation, elevation of NAD(+)/NADP(+) ratio activates SIRT1, leading to histone H3 deacetylation followed by dimethylation of H3 at 'Lys-9' (H3K9me2) by SUV39H1 and the formation of silent chromatin in the rDNA locus. In the complex, RRP8 binds to H3K9me2 and pr [...] (455 aa) |
| | SLC38A2 | Solute carrier family 38 member 2. (509 aa) |
| | ATG5 | Autophagy protein 5; Involved in autophagic vesicle formation. (275 aa) |
| | LAMP2 | Lysosomal associated membrane protein 2. (458 aa) |
| | LEP | Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa) |
| | SIRT1 | Sirtuin 1. (602 aa) |
| | AVPR1A | Vasopressin V1a receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. (418 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | AADACL4 | Arylacetamide deacetylase like 4. (401 aa) |
| | KLF10 | Kruppel like factor 10. (480 aa) |
| | IMPACT | Impact RWD domain protein. (297 aa) |
| | I3MU88_ICTTR | Uncharacterized protein. (83 aa) |
| | NUPR2 | Nuclear protein 2, transcriptional regulator. (85 aa) |
| | BCL2 | BCL2 apoptosis regulator. (195 aa) |
| | SFRP1 | Secreted frizzled related protein 1. (314 aa) |
| | BRSK2 | BR serine/threonine kinase 2. (701 aa) |
| | SESN1 | Sestrin 1. (552 aa) |
| | Cbwd1 | CobW C-terminal domain-containing protein. (395 aa) |
| | EHMT2 | Euchromatic histone lysine methyltransferase 2. (1254 aa) |
| | RNF167 | Ring finger protein 167. (345 aa) |
| | FOXA3 | Forkhead box A3. (349 aa) |
| | TLE5 | TLE family member 5, transcriptional modulator. (182 aa) |
| | JMY | Junction mediating and regulatory protein, p53 cofactor. (982 aa) |
| | RNASE4 | Ribonuclease A family member 4; Belongs to the pancreatic ribonuclease family. (148 aa) |
| | MAX | MYC associated factor X. (160 aa) |
| | FNIP1 | Folliculin interacting protein 1. (1164 aa) |
| | DCTPP1 | dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (171 aa) |
| | WNT9B | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (373 aa) |
| | BHLHA15 | Basic helix-loop-helix family member a15. (190 aa) |
| | ADNP | Activity dependent neuroprotector homeobox. (1103 aa) |
| | WDR45B | WD repeat domain 45B. (344 aa) |
| | NIM1K | NIM1 serine/threonine protein kinase; Belongs to the protein kinase superfamily. (436 aa) |
| | Vcam1 | Vascular cell adhesion molecule 1. (657 aa) |
| | NUAK1 | NUAK family kinase 1. (629 aa) |
| | SIPA1 | Signal-induced proliferation-associated 1. (1032 aa) |
| | COMT | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. (265 aa) |
| | CADPS2 | Calcium dependent secretion activator 2. (1234 aa) |
| | RIPOR1 | RHO family interacting cell polarization regulator 1. (1209 aa) |
| | CDKN1A | Cyclin dependent kinase inhibitor 1A. (162 aa) |
| | NUAK2 | NUAK family kinase 2. (631 aa) |
| | PPM1D | Protein phosphatase, Mg2+/Mn2+ dependent 1D. (605 aa) |
| | Pdk4 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial; Kinase that plays a key role in regulation of glucose and fatty acid metabolism and homeostasis via phosphorylation of the pyruvate dehydrogenase subunits PDHA1 and PDHA2. This inhibits pyruvate dehydrogenase activity, and thereby regulates metabolite flux through the tricarboxylic acid cycle, down-regulates aerobic respiration and inhibits the formation of acetyl-coenzyme A from pyruvate. Inhibition of pyruvate dehydrogenase decreases glucose utilization and increases fat metabolism in response to prolonge [...] (412 aa) |
| | GAS2L1 | Growth arrest specific 2 like 1. (676 aa) |
| | TP53 | Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (391 aa) |
| | INHBB | Inhibin subunit beta B. (336 aa) |
| | PLIN3 | Perilipin; Belongs to the perilipin family. (465 aa) |
| | AMBRA1 | Autophagy and beclin 1 regulator 1. (1240 aa) |
| | FOXA2 | Forkhead box A2. (463 aa) |
| | BMT2 | S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (405 aa) |
| | Slc7a5 | Uncharacterized protein. (448 aa) |
| | RNF152 | Ring finger protein 152. (203 aa) |
| | PIM1 | Serine/threonine-protein kinase; Proto-oncogene with serine/threonine kinase activity involved in cell survival and cell proliferation. Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. PIM subfamily. (313 aa) |
| | AOC1 | Amine oxidase. (688 aa) |
| | BECN2 | Beclin 2. (412 aa) |
| | CDKN2B | Cyclin dependent kinase inhibitor 2B. (162 aa) |
| | I3N9L4_ICTTR | Protein kinase domain-containing protein. (388 aa) |
| | ZC3H12A | Zinc finger CCCH-type containing 12A. (599 aa) |
| | GAS6 | Growth arrest specific 6. (654 aa) |
| | GSDMD | Gasdermin D. (489 aa) |
| | TNRC6A | Trinucleotide repeat containing adaptor 6A. (1990 aa) |
| | JUN | Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (334 aa) |
| | Foxo3 | Forkhead box O3. (673 aa) |
| | GABARAPL2 | GABA type A receptor associated protein like 2. (123 aa) |
| | USF2 | Upstream transcription factor 2, c-fos interacting. (344 aa) |
| | ATG14 | Autophagy related 14. (492 aa) |
| | MYOD1 | Myogenic factor; Induces fibroblasts to differentiate into myoblasts. Acts as a transcriptional activator that promotes transcription of muscle- specific target genes and plays a role in muscle differentiation. (317 aa) |
| | KIF26A | Kinesin family member 26A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1891 aa) |
| | GCGR | Glucagon receptor; Belongs to the G-protein coupled receptor 2 family. (481 aa) |
| | I3NFV0_ICTTR | Uncharacterized protein. (216 aa) |
| | LOC101975488 | Uncharacterized protein. (456 aa) |
| | LOC101968945 | Uncharacterized protein; Belongs to the peptidase C1 family. (339 aa) |
| | DICER1 | Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1904 aa) |
| | ATF4 | Activating transcription factor 4. (352 aa) |
| | DSPP | Dentin sialophosphoprotein. (1075 aa) |
| | ENSSTOP00000024016 | RRM domain-containing protein. (234 aa) |
| | PRKAA1 | Non-specific serine/threonine protein kinase. (561 aa) |
| | WDR59 | WD repeat domain 59. (916 aa) |
| | TXN2 | Thioredoxin 2. (166 aa) |
| | MYH13 | Myosin heavy chain 13; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1946 aa) |
| | Becn1 | Beclin 1. (448 aa) |
| | USF1 | Upstream transcription factor 1. (310 aa) |
| | FAM107A | Family with sequence similarity 107 member A. (144 aa) |
| | XPR1 | Xenotropic and polytropic retrovirus receptor 1. (689 aa) |
| | COL1A1 | Collagen type I alpha 1 chain. (1268 aa) |
| | FOLR1 | Folate receptor alpha. (255 aa) |
| | ENSSTOP00000025928 | Rho-GAP domain-containing protein. (67 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (726 aa) |
| | GDAP1 | Ganglioside induced differentiation associated protein 1; Belongs to the GST superfamily. (358 aa) |
| | LOC101968724 | Uncharacterized protein. (292 aa) |
| | PTPRC | Protein tyrosine phosphatase receptor type C. (1180 aa) |
| | HMOX1 | Heme oxygenase 1. (288 aa) |
| | LOC101964795 | Uncharacterized protein. (108 aa) |
| | Cbs | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. (555 aa) |
| | EIF4G1 | Eukaryotic translation initiation factor 4 gamma 1. (1611 aa) |
| | PRKAG2 | Protein kinase AMP-activated non-catalytic subunit gamma 2. (542 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (492 aa) |
| | CPEB4 | Cytoplasmic polyadenylation element binding protein 4. (729 aa) |
| | TFEB | Transcription factor EB. (474 aa) |
| | POSTN | Periostin. (836 aa) |
| | ENSSTOP00000027444 | Uncharacterized protein; Belongs to the LDH/MDH superfamily. (301 aa) |
| | VPS41 | Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (854 aa) |
| | KCNB1 | Potassium voltage-gated channel subfamily B member 1; Belongs to the potassium channel family. (859 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | ENSSTOP00000028903 | Uncharacterized protein. (316 aa) |
| | ITFG2 | Integrin alpha FG-GAP repeat containing 2. (444 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (546 aa) |
| | Depdc5 | DEP domain-containing protein. (1482 aa) |
| | AXL | AXL receptor tyrosine kinase. (887 aa) |
| | NPRL3 | NPR3 like, GATOR1 complex subunit. (569 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (1152 aa) |
| | LYN | Tyrosine-protein kinase. (512 aa) |
| | Wdr45 | Uncharacterized protein. (360 aa) |
| | LOC101961297 | Uncharacterized protein. (302 aa) |
| | FOLR2 | Folate receptor beta. (252 aa) |
| | PRKAB2 | Protein kinase AMP-activated non-catalytic subunit beta 2. (272 aa) |
| | MTMR3 | Myotubularin related protein 3. (1006 aa) |
| | RPTOR | Regulatory associated protein of MTOR complex 1. (1335 aa) |
| | TCF7L2 | Transcription factor 7 like 2. (514 aa) |
| | NCOA1 | Nuclear receptor coactivator. (1442 aa) |
| | SH3GLB1 | SH3 domain containing GRB2 like, endophilin B1. (387 aa) |
| | SLC1A2 | Amino acid transporter. (575 aa) |
| | STK26 | Serine/threonine kinase 26. (416 aa) |
| | ATP2B1 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1220 aa) |
| | ENSSTOP00000031875 | Uncharacterized protein. (274 aa) |
| | VDR | Vitamin D receptor. (423 aa) |
| | SIK2 | Salt inducible kinase 2. (930 aa) |
| | ENSSTOP00000032132 | RRM domain-containing protein. (282 aa) |
| | MTOR | Serine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa) |
| | KIAA1324 | KIAA1324. (1013 aa) |
| | PLIN2 | Perilipin; Belongs to the perilipin family. (443 aa) |
