32 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
	TYMS	Uncharacterized protein. (218 aa)
	CYP1B1	Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
	GPI	Glucose-6-phosphate isomerase; Belongs to the GPI family. (558 aa)
	TSPO	Translocator protein. (169 aa)
	FOSL1	FOS like 1, AP-1 transcription factor subunit. (275 aa)
	ABHD2	Abhydrolase domain containing 2. (425 aa)
	BAD	BCL2 associated agonist of cell death. (208 aa)
	GABRB1	Gamma-aminobutyric acid type A receptor beta1 subunit; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (474 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
	IGF1R	Tyrosine-protein kinase receptor. (1368 aa)
	TXNIP	Thioredoxin interacting protein. (391 aa)
	LOC101967926	Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (124 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	LOC101976546	PKS_ER domain-containing protein. (375 aa)
	SOX10	SRY-box transcription factor 10. (466 aa)
	PTGER2	Prostaglandin E receptor 2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
	ACOD1	Aconitate decarboxylase 1. (473 aa)
	OXTR	Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (391 aa)
	GJB2	Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (226 aa)
	LOC101967640	Uncharacterized protein; Belongs to the vasopressin/oxytocin family. (125 aa)
	NCOA2	Nuclear receptor coactivator. (1465 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (784 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
	FOSB	FosB proto-oncogene, AP-1 transcription factor subunit. (338 aa)
	ENSSTOP00000024982	GRAM domain-containing protein. (244 aa)
	NR1H3	Nuclear receptor subfamily 1 group H member 3. (444 aa)
	Wbp2	GRAM domain-containing protein. (261 aa)
	SREBF1	Sterol regulatory element binding transcription factor 1. (1152 aa)
	NCOA1	Nuclear receptor coactivator. (1442 aa)
	UBE3A	Ubiquitin-protein ligase E3A; E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and transfers it to its substrates. (874 aa)
	TRERF1	Transcriptional regulating factor 1. (1213 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACOD1	TYMS	ENSSTOP00000017859	ENSSTOP00000000814	Aconitate decarboxylase 1.	Uncharacterized protein.	0.580
CAV1	IGF1R	ENSSTOP00000015394	ENSSTOP00000010241	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	Tyrosine-protein kinase receptor.	0.667
FOSB	FOSL1	ENSSTOP00000022980	ENSSTOP00000002942	FosB proto-oncogene, AP-1 transcription factor subunit.	FOS like 1, AP-1 transcription factor subunit.	0.934
FOSB	NCOA1	ENSSTOP00000022980	ENSSTOP00000031631	FosB proto-oncogene, AP-1 transcription factor subunit.	Nuclear receptor coactivator.	0.602
FOSB	NCOA2	ENSSTOP00000022980	ENSSTOP00000021326	FosB proto-oncogene, AP-1 transcription factor subunit.	Nuclear receptor coactivator.	0.602
FOSL1	FOSB	ENSSTOP00000002942	ENSSTOP00000022980	FOS like 1, AP-1 transcription factor subunit.	FosB proto-oncogene, AP-1 transcription factor subunit.	0.934
GPI	TYMS	ENSSTOP00000002308	ENSSTOP00000000814	Glucose-6-phosphate isomerase; Belongs to the GPI family.	Uncharacterized protein.	0.691
IGF1R	CAV1	ENSSTOP00000010241	ENSSTOP00000015394	Tyrosine-protein kinase receptor.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.667
IGF1R	NR1H3	ENSSTOP00000010241	ENSSTOP00000027881	Tyrosine-protein kinase receptor.	Nuclear receptor subfamily 1 group H member 3.	0.448
IGF1R	TGFB1	ENSSTOP00000010241	ENSSTOP00000008874	Tyrosine-protein kinase receptor.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.493
IGF1R	TGFB2	ENSSTOP00000010241	ENSSTOP00000001118	Tyrosine-protein kinase receptor.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.417
LOC101967640	OXTR	ENSSTOP00000020601	ENSSTOP00000018112	Uncharacterized protein; Belongs to the vasopressin/oxytocin family.	Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.899
LOC101967926	OXTR	ENSSTOP00000013478	ENSSTOP00000018112	Uncharacterized protein; Belongs to the vasopressin/oxytocin family.	Oxytocin receptor; Receptor for oxytocin. The activity of this receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system; Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily.	0.899
NCOA1	FOSB	ENSSTOP00000031631	ENSSTOP00000022980	Nuclear receptor coactivator.	FosB proto-oncogene, AP-1 transcription factor subunit.	0.602
NCOA1	NCOA2	ENSSTOP00000031631	ENSSTOP00000021326	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.976
NCOA1	NR1H3	ENSSTOP00000031631	ENSSTOP00000027881	Nuclear receptor coactivator.	Nuclear receptor subfamily 1 group H member 3.	0.970
NCOA2	FOSB	ENSSTOP00000021326	ENSSTOP00000022980	Nuclear receptor coactivator.	FosB proto-oncogene, AP-1 transcription factor subunit.	0.602
NCOA2	NCOA1	ENSSTOP00000021326	ENSSTOP00000031631	Nuclear receptor coactivator.	Nuclear receptor coactivator.	0.976
NCOA2	NR1H3	ENSSTOP00000021326	ENSSTOP00000027881	Nuclear receptor coactivator.	Nuclear receptor subfamily 1 group H member 3.	0.966
NR1H3	IGF1R	ENSSTOP00000027881	ENSSTOP00000010241	Nuclear receptor subfamily 1 group H member 3.	Tyrosine-protein kinase receptor.	0.448