STRINGSTRING
JAK2 JAK2 RNF112 RNF112 PRKD1 PRKD1 TP53INP1 TP53INP1 PRKCD PRKCD DDIAS DDIAS OXR1 OXR1 SP1 SP1 MGST1 MGST1 DAPK1 DAPK1 XRCC1 XRCC1 TRPM2 TRPM2 GPX1 GPX1 CD36 CD36 MT-ND1 MT-ND1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
JAK2Tyrosine-protein kinase. (1132 aa)
RNF112Ring finger protein 112. (645 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (843 aa)
TP53INP1Tumor protein p53 inducible nuclear protein 1. (239 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
DDIASDNA damage induced apoptosis suppressor. (887 aa)
OXR1Oxidation resistance 1. (875 aa)
SP1Sp1 transcription factor. (788 aa)
MGST1Microsomal glutathione S-transferase 1. (155 aa)
DAPK1Death associated protein kinase 1. (1432 aa)
XRCC1X-ray repair cross complementing 1. (632 aa)
TRPM2Transient receptor potential cation channel subfamily M member 2. (1499 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (201 aa)
CD36CD36 molecule; Belongs to the CD36 family. (473 aa)
MT-ND1NADH-ubiquinone oxidoreductase chain 1; Belongs to the complex I subunit 1 family. (318 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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