(11 nodes) Integrin activation network (Ictidomys tridecemlineatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MZB1	Marginal zone B and B1 cell specific protein. (188 aa)
	FN1	Fibronectin 1. (2474 aa)
	TLN1	Talin 1. (2541 aa)
	Col16a1	Uncharacterized protein. (61 aa)
	CXCL12	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
	FERMT2	Fermitin family member 2. (680 aa)
	Krit1	Uncharacterized protein. (736 aa)
	ITGB1BP1	Integrin subunit beta 1 binding protein 1. (200 aa)
	ENSSTOP00000025996	Uncharacterized protein. (366 aa)
	CX3CL1	C-X3-C motif chemokine ligand 1. (397 aa)
	FERMT3	Fermitin family member 3. (663 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CX3CL1	CXCL12	ENSSTOP00000023014	ENSSTOP00000005317	C-X3-C motif chemokine ligand 1.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.848
CXCL12	CX3CL1	ENSSTOP00000005317	ENSSTOP00000023014	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	C-X3-C motif chemokine ligand 1.	0.848
CXCL12	FN1	ENSSTOP00000005317	ENSSTOP00000002458	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	Fibronectin 1.	0.543
FERMT2	FERMT3	ENSSTOP00000007688	ENSSTOP00000012789	Fermitin family member 2.	Fermitin family member 3.	0.705
FERMT3	FERMT2	ENSSTOP00000012789	ENSSTOP00000007688	Fermitin family member 3.	Fermitin family member 2.	0.705
FERMT3	TLN1	ENSSTOP00000012789	ENSSTOP00000004644	Fermitin family member 3.	Talin 1.	0.573
FN1	CXCL12	ENSSTOP00000002458	ENSSTOP00000005317	Fibronectin 1.	C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family.	0.543
FN1	TLN1	ENSSTOP00000002458	ENSSTOP00000004644	Fibronectin 1.	Talin 1.	0.666
ITGB1BP1	Krit1	ENSSTOP00000026199	ENSSTOP00000030339	Integrin subunit beta 1 binding protein 1.	Uncharacterized protein.	0.973
ITGB1BP1	TLN1	ENSSTOP00000026199	ENSSTOP00000004644	Integrin subunit beta 1 binding protein 1.	Talin 1.	0.457
Krit1	ITGB1BP1	ENSSTOP00000030339	ENSSTOP00000026199	Uncharacterized protein.	Integrin subunit beta 1 binding protein 1.	0.973
Krit1	TLN1	ENSSTOP00000030339	ENSSTOP00000004644	Uncharacterized protein.	Talin 1.	0.446
TLN1	FERMT3	ENSSTOP00000004644	ENSSTOP00000012789	Talin 1.	Fermitin family member 3.	0.573
TLN1	FN1	ENSSTOP00000004644	ENSSTOP00000002458	Talin 1.	Fibronectin 1.	0.666
TLN1	ITGB1BP1	ENSSTOP00000004644	ENSSTOP00000026199	Talin 1.	Integrin subunit beta 1 binding protein 1.	0.457
TLN1	Krit1	ENSSTOP00000004644	ENSSTOP00000030339	Talin 1.	Uncharacterized protein.	0.446