STRINGSTRING
AGTR2 AGTR2 PPP1R12A PPP1R12A TMEM130 TMEM130 ITGA1 ITGA1 CDH5 CDH5 TGFB1 TGFB1 PTPA PTPA SYMPK SYMPK MAGI2 MAGI2 LRRC46 LRRC46 CAMTA1 CAMTA1 PRKCD PRKCD PIN1 PIN1 SMPD1 SMPD1 GBA GBA CDCA2 CDCA2 JAK2 JAK2 PTPRC PTPRC PTBP1 PTBP1 DLC1 DLC1 VRK3 VRK3 PPP1R16B PPP1R16B CNEP1R1 CNEP1R1 SPPL3 SPPL3 PINK1 PINK1 PDGFRB PDGFRB PPP1R15B PPP1R15B GNA12 GNA12 SLC39A10 SLC39A10 ANKLE2 ANKLE2 PPP2R5D PPP2R5D NSMF NSMF AMBRA1 AMBRA1 LRRC43 LRRC43 Ppp1r7 Ppp1r7 Ppp1r14d Ppp1r14d PAWR PAWR PPP2R5A PPP2R5A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
AGTR2Angiotensin II receptor type 2; Belongs to the G-protein coupled receptor 1 family. (361 aa)
PPP1R12AProtein phosphatase 1 regulatory subunit. (1005 aa)
TMEM130Transmembrane protein 130. (338 aa)
ITGA1Integrin subunit alpha 1; Belongs to the integrin alpha chain family. (1179 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PTPASerine/threonine-protein phosphatase 2A activator; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (288 aa)
SYMPKSymplekin. (1271 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1188 aa)
LRRC46Leucine rich repeat containing 46. (321 aa)
CAMTA1Calmodulin binding transcription activator 1. (1665 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (676 aa)
PIN1Peptidyl-prolyl cis-trans isomerase. (163 aa)
SMPD1Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (627 aa)
GBAGlucosylceramidase. (516 aa)
CDCA2Cell division cycle associated 2. (910 aa)
JAK2Tyrosine-protein kinase. (1132 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1180 aa)
PTBP1Polypyrimidine tract binding protein 1. (557 aa)
DLC1DLC1 Rho GTPase activating protein. (1125 aa)
VRK3VRK serine/threonine kinase 3. (453 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (568 aa)
CNEP1R1CTD nuclear envelope phosphatase 1 regulatory subunit 1. (125 aa)
SPPL3Signal peptide peptidase like 3. (374 aa)
PINK1PTEN induced kinase 1. (574 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1112 aa)
PPP1R15BProtein phosphatase 1 regulatory subunit 15B. (713 aa)
GNA12G protein subunit alpha 12. (343 aa)
SLC39A10Solute carrier family 39 member 10. (830 aa)
ANKLE2Ankyrin repeat and LEM domain containing 2. (892 aa)
PPP2R5DSerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (603 aa)
NSMFNMDA receptor synaptonuclear signaling and neuronal migration factor. (530 aa)
AMBRA1Autophagy and beclin 1 regulator 1. (1240 aa)
LRRC43Leucine rich repeat containing 43. (660 aa)
Ppp1r7LRRcap domain-containing protein. (360 aa)
Ppp1r14dUncharacterized protein. (140 aa)
PAWRPro-apoptotic WT1 regulator. (340 aa)
PPP2R5ASerine/threonine-protein phosphatase 2A 56 kDa regulatory subunit; The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment. (486 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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