STRINGSTRING
EYA1 EYA1 ENG ENG TBX2 TBX2 FOXH1 FOXH1 CHD7 CHD7 FKBP10 FKBP10 COL3A1 COL3A1 NPRL3 NPRL3 PROX1 PROX1 FGF8 FGF8 JAG1 JAG1 RBPJ RBPJ EFEMP2 EFEMP2 PDGFRB PDGFRB HEY1 HEY1 KAT6A KAT6A HES1 HES1 HEY2 HEY2 SIX1 SIX1 SEC24B SEC24B TFAP2B TFAP2B SRF SRF BMPR1A BMPR1A LRP1 LRP1 MYLK MYLK ACVRL1 ACVRL1 ADAMTS9 ADAMTS9 TGFB2 TGFB2 DLL4 DLL4 TBX1 TBX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
ENGEndoglin. (463 aa)
TBX2T-box transcription factor 2. (712 aa)
FOXH1Forkhead box H1. (370 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2997 aa)
FKBP10Peptidylprolyl isomerase. (583 aa)
COL3A1Collagen type III alpha 1 chain. (1462 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (569 aa)
PROX1Prospero homeobox 1. (737 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
RBPJRecombination signal binding protein for immunoglobulin kappa J region. (522 aa)
EFEMP2EGF containing fibulin extracellular matrix protein 2. (443 aa)
PDGFRBPlatelet-derived growth factor receptor beta; Tyrosine-protein kinase that acts as cell-surface receptor for homodimeric PDGFB and PDGFD and for heterodimers formed by PDGFA and PDGFB, and plays an essential role in the regulation of embryonic development, cell proliferation, survival, differentiation, chemotaxis and migration. Plays an essential role in blood vessel development by promoting proliferation, migration and recruitment of pericytes and smooth muscle cells to endothelial cells. (1112 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
KAT6AHistone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (2017 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
SIX1SIX homeobox 1. (284 aa)
SEC24BSEC24 homolog B, COPII coat complex component. (1219 aa)
TFAP2BTranscription factor AP-2 beta. (460 aa)
SRFSerum response factor. (505 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (532 aa)
LRP1LDL receptor related protein 1. (4508 aa)
MYLKMyosin light chain kinase. (1897 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1864 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (685 aa)
TBX1T-box transcription factor 1. (406 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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