Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| AADAT | AFMID | ENSSTOP00000021589 | ENSSTOP00000014673 | Aminoadipate aminotransferase. | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 0.897 |
| AADAT | CBR3 | ENSSTOP00000021589 | ENSSTOP00000028670 | Aminoadipate aminotransferase. | Carbonyl reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. | 0.446 |
| AADAT | COQ6 | ENSSTOP00000021589 | ENSSTOP00000027073 | Aminoadipate aminotransferase. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.816 |
| AADAT | ENSSTOP00000029768 | ENSSTOP00000021589 | ENSSTOP00000029768 | Aminoadipate aminotransferase. | Aminotran_1_2 domain-containing protein. | 0.786 |
| AADAT | Got2 | ENSSTOP00000021589 | ENSSTOP00000031640 | Aminoadipate aminotransferase. | Aminotran_1_2 domain-containing protein. | 0.786 |
| AADAT | IDO1 | ENSSTOP00000021589 | ENSSTOP00000011828 | Aminoadipate aminotransferase. | Indoleamine 2,3-dioxygenase 1. | 0.832 |
| AADAT | IDO2 | ENSSTOP00000021589 | ENSSTOP00000020032 | Aminoadipate aminotransferase. | Indoleamine 2,3-dioxygenase 2. | 0.831 |
| AADAT | KMO | ENSSTOP00000021589 | ENSSTOP00000011382 | Aminoadipate aminotransferase. | Kynurenine 3-monooxygenase; Catalyzes the hydroxylation of L-kynurenine (L-Kyn) to form 3-hydroxy-L-kynurenine (L-3OHKyn). Required for synthesis of quinolinic acid, a neurotoxic NMDA receptor antagonist and potential endogenous inhibitor of NMDA receptor signaling in axonal targeting, synaptogenesis and apoptosis during brain development. Quinolinic acid may also affect NMDA receptor signaling in pancreatic beta cells, osteoblasts, myocardial cells, and the gastrointestinal tract. | 0.936 |
| AADAT | KYNU | ENSSTOP00000021589 | ENSSTOP00000008342 | Aminoadipate aminotransferase. | Kynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. Has a preference for the L-3-hydroxy form. Also has cysteine-conjugate-beta-lyase activity. Belongs to the kynureninase family. | 0.926 |
| AADAT | Kyat1 | ENSSTOP00000021589 | ENSSTOP00000029563 | Aminoadipate aminotransferase. | Aminotran_1_2 domain-containing protein. | 0.927 |
| AADAT | Kyat3 | ENSSTOP00000021589 | ENSSTOP00000016640 | Aminoadipate aminotransferase. | Aminotran_1_2 domain-containing protein. | 0.919 |
| AADAT | LOC101962681 | ENSSTOP00000021589 | ENSSTOP00000029178 | Aminoadipate aminotransferase. | Aminotran_1_2 domain-containing protein. | 0.786 |
| AADAT | LOC101977971 | ENSSTOP00000021589 | ENSSTOP00000025592 | Aminoadipate aminotransferase. | Aminotran_1_2 domain-containing protein. | 0.786 |
| AFMID | AADAT | ENSSTOP00000014673 | ENSSTOP00000021589 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Aminoadipate aminotransferase. | 0.897 |
| AFMID | COQ5 | ENSSTOP00000014673 | ENSSTOP00000011255 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial; Methyltransferase required for the conversion of 2- polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl- 6-methoxy-1,4-benzoquinol (DMQH2). | 0.608 |
| AFMID | COQ6 | ENSSTOP00000014673 | ENSSTOP00000027073 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Ubiquinone biosynthesis monooxygenase COQ6, mitochondrial; FAD-dependent monooxygenase required for the C5-ring hydroxylation during ubiquinone biosynthesis. Catalyzes the hydroxylation of 3-polyprenyl-4-hydroxybenzoic acid to 3-polyprenyl- 4,5-dihydroxybenzoic acid. The electrons required for the hydroxylation reaction may be funneled indirectly from NADPH via a ferredoxin/ferredoxin reductase system to COQ6. | 0.622 |
| AFMID | FDXR | ENSSTOP00000014673 | ENSSTOP00000008651 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | NADPH:adrenodoxin oxidoreductase, mitochondrial. | 0.405 |
| AFMID | GLO1 | ENSSTOP00000014673 | ENSSTOP00000005197 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Lactoylglutathione lyase; Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. | 0.514 |
| AFMID | IDO1 | ENSSTOP00000014673 | ENSSTOP00000011828 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Indoleamine 2,3-dioxygenase 1. | 0.908 |
| AFMID | IDO2 | ENSSTOP00000014673 | ENSSTOP00000020032 | Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites. | Indoleamine 2,3-dioxygenase 2. | 0.932 |
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