STRINGSTRING
EPCAM EPCAM CLDN11 CLDN11 CLDN17 CLDN17 PKN2 PKN2 DDX58 DDX58 Actg1 Actg1 LOC101973389 LOC101973389 CDH5 CDH5 SHROOM2 SHROOM2 MAGI3 MAGI3 JAM3 JAM3 CLDN18 CLDN18 MTDH MTDH CYTH1 CYTH1 Cgn Cgn WNK4 WNK4 BVES BVES PDCD6IP PDCD6IP FRMD6 FRMD6 Igsf5 Igsf5 PRKCI PRKCI AMOTL1 AMOTL1 CDH1 CDH1 MAGI1 MAGI1 FRMD1 FRMD1 AMOT AMOT APC APC CYTH3 CYTH3 RAPGEF2 RAPGEF2 ENSSTOP00000031475 ENSSTOP00000031475 CRB3 CRB3 UBN1 UBN1 FRMD4A FRMD4A F11R F11R CAMSAP3 CAMSAP3 ENSSTOP00000030397 ENSSTOP00000030397 WNK3 WNK3 CGNL1 CGNL1 LSR LSR MARVELD2 MARVELD2 SAPCD2 SAPCD2 Ocel1 Ocel1 VCL VCL CLMP CLMP FRMPD2 FRMPD2 MAGI2 MAGI2 MXRA8 MXRA8 MPP5 MPP5 PLEKHA7 PLEKHA7 CLDN7 CLDN7 Cdk4 Cdk4 CLDN15 CLDN15 ARHGEF2 ARHGEF2 CLDN2 CLDN2 CYTH2 CYTH2 CLDN19 CLDN19 ATP7B ATP7B ESAM ESAM I3MRS9_ICTTR I3MRS9_ICTTR AMOTL2 AMOTL2 CLDN6 CLDN6 SHROOM1 SHROOM1 PMP22 PMP22 Ect2 Ect2 RAP2B RAP2B CLDN23 CLDN23 CCDC85C CCDC85C LOC101954496 LOC101954496 IL16 IL16 MPP7 MPP7 MAPK15 MAPK15 FRMD4B FRMD4B CLDN3 CLDN3 ACTL8 ACTL8 CLDN12 CLDN12 TJP3 TJP3 C1QTNF5 C1QTNF5 PARD6A PARD6A CCND1 CCND1 CLDN5 CLDN5 ARHGAP17 ARHGAP17 CLDN20 CLDN20 CLDN25 CLDN25 NECTIN3 NECTIN3 MPDZ MPDZ AJM1 AJM1 OCLN OCLN CLDN14 CLDN14 I3NCC6_ICTTR I3NCC6_ICTTR CLDN4 CLDN4 LIN7B LIN7B CRB2 CRB2 NECTIN1 NECTIN1 CXADR CXADR AFDN AFDN ENSSTOP00000024190 ENSSTOP00000024190 DLG3 DLG3 LIN7C LIN7C KIFC3 KIFC3 ENSSTOP00000025680 ENSSTOP00000025680 SHROOM3 SHROOM3 CTNND1 CTNND1 LIN7A LIN7A ILDR2 ILDR2 Jaml Jaml PATJ PATJ PARD3 PARD3 PARD6G PARD6G CTNNB1 CTNNB1 Actb Actb LOC101977927 LOC101977927 LOC101978211 LOC101978211 Sh3bp1 Sh3bp1 STRN STRN TGFBR1 TGFBR1 ADCYAP1R1 ADCYAP1R1 PRKCZ PRKCZ EPB41L4B EPB41L4B POF1B POF1B Rab13 Rab13 Tjp2 Tjp2 TJP1 TJP1 TJAP1 TJAP1 PARD3B PARD3B CLDN10 CLDN10 ILDR1 ILDR1 CLDN9 CLDN9 VAPA VAPA CLDN1 CLDN1 PARD6B PARD6B CRB1 CRB1 NECTIN2 NECTIN2 CLDN16 CLDN16
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EPCAMEpithelial cell adhesion molecule. (290 aa)
CLDN11Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (207 aa)
CLDN17Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
PKN2Protein kinase N2. (982 aa)
DDX58DExD/H-box helicase 58. (925 aa)
Actg1Uncharacterized protein. (375 aa)
LOC101973389Uncharacterized protein. (182 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
SHROOM2Shroom family member 2. (1598 aa)
MAGI3Membrane associated guanylate kinase, WW and PDZ domain containing 3. (1452 aa)
JAM3Junctional adhesion molecule 3. (310 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (261 aa)
MTDHMetadherin. (581 aa)
CYTH1Cytohesin 1. (389 aa)
CgnMyosin_tail_1 domain-containing protein. (1195 aa)
WNK4WNK lysine deficient protein kinase 4. (1246 aa)
BVESBlood vessel epicardial substance. (360 aa)
PDCD6IPProgrammed cell death 6 interacting protein. (875 aa)
FRMD6FERM domain containing 6. (622 aa)
Igsf5Uncharacterized protein. (371 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (582 aa)
AMOTL1Angiomotin like 1. (851 aa)
CDH1Cadherin 1; Cadherins are calcium-dependent cell adhesion proteins. (885 aa)
MAGI1Membrane associated guanylate kinase, WW and PDZ domain containing 1. (1337 aa)
FRMD1FERM domain containing 1. (545 aa)
AMOTAngiomotin. (1068 aa)
APCAPC regulator of WNT signaling pathway. (2865 aa)
CYTH3Cytohesin 3. (399 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1650 aa)
ENSSTOP00000031475Uncharacterized protein; Belongs to the actin family. (173 aa)
CRB3Crumbs cell polarity complex component 3. (122 aa)
UBN1Ubinuclein 1. (1135 aa)
FRMD4AFERM domain containing 4A. (1055 aa)
F11RF11 receptor. (298 aa)
CAMSAP3Calmodulin regulated spectrin associated protein family member 3. (1263 aa)
ENSSTOP00000030397Uncharacterized protein; Belongs to the actin family. (148 aa)
WNK3WNK lysine deficient protein kinase 3. (1745 aa)
CGNL1Cingulin like 1. (1298 aa)
LSRLipolysis stimulated lipoprotein receptor. (600 aa)
MARVELD2MARVEL domain containing 2. (558 aa)
SAPCD2Suppressor APC domain containing 2. (387 aa)
Ocel1Occludin_ELL domain-containing protein. (125 aa)
VCLVinculin. (1134 aa)
CLMPCXADR like membrane protein. (373 aa)
FRMPD2FERM and PDZ domain containing 2. (1297 aa)
MAGI2Membrane associated guanylate kinase, WW and PDZ domain containing 2. (1188 aa)
MXRA8Matrix remodeling associated 8. (443 aa)
MPP5Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
PLEKHA7Pleckstrin homology domain containing A7. (1224 aa)
CLDN7Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
Cdk4Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
CLDN15Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (227 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (869 aa)
CLDN2Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (230 aa)
CYTH2Uncharacterized protein. (410 aa)
CLDN19Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (224 aa)
ATP7BATPase copper transporting beta. (1464 aa)
ESAMEndothelial cell adhesion molecule. (393 aa)
I3MRS9_ICTTRPDZ domain-containing protein. (197 aa)
AMOTL2Angiomotin like 2. (774 aa)
CLDN6Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (221 aa)
SHROOM1Shroom family member 1. (852 aa)
PMP22Peripheral myelin protein 22; Might be involved in growth regulation, and in myelinization in the peripheral nervous system; Belongs to the PMP-22/EMP/MP20 family. (160 aa)
Ect2Uncharacterized protein. (188 aa)
RAP2BRAP2B, member of RAS oncogene family. (183 aa)
CLDN23Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (294 aa)
CCDC85CCoiled-coil domain containing 85C. (416 aa)
LOC101954496Uncharacterized protein. (346 aa)
IL16Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1329 aa)
MPP7Membrane palmitoylated protein 7; Belongs to the MAGUK family. (557 aa)
MAPK15Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (554 aa)
FRMD4BFERM domain containing 4B. (1017 aa)
CLDN3Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
ACTL8Actin like 8; Belongs to the actin family. (366 aa)
CLDN12Claudin 12. (244 aa)
TJP3Tight junction protein 3; Belongs to the MAGUK family. (918 aa)
C1QTNF5C1q and TNF related 5. (243 aa)
PARD6APar-6 family cell polarity regulator alpha. (345 aa)
CCND1Cyclin D1. (250 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ARHGAP17Rho GTPase activating protein 17. (813 aa)
CLDN20Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (219 aa)
CLDN25Claudin 25. (229 aa)
NECTIN3Nectin cell adhesion molecule 3. (443 aa)
MPDZMultiple PDZ domain crumbs cell polarity complex component. (2073 aa)
AJM1Apical junction component 1 homolog. (973 aa)
OCLNOccludin; May play a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier. Belongs to the ELL/occludin family. (524 aa)
CLDN14Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (239 aa)
I3NCC6_ICTTRUncharacterized protein; Belongs to the actin family. (340 aa)
CLDN4Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (209 aa)
LIN7BProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (207 aa)
CRB2Crumbs cell polarity complex component 2. (1288 aa)
NECTIN1Nectin cell adhesion molecule 1. (516 aa)
CXADRUncharacterized protein. (352 aa)
AFDNAfadin, adherens junction formation factor. (1801 aa)
ENSSTOP00000024190Protein kinase domain-containing protein. (266 aa)
DLG3Discs large MAGUK scaffold protein 3; Belongs to the MAGUK family. (867 aa)
LIN7CProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (197 aa)
KIFC3Kinesin family member C3; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1009 aa)
ENSSTOP00000025680Uncharacterized protein. (156 aa)
SHROOM3Shroom family member 3. (1914 aa)
CTNND1Catenin delta 1. (967 aa)
LIN7AProtein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (232 aa)
ILDR2Immunoglobulin like domain containing receptor 2. (427 aa)
JamlUncharacterized protein. (374 aa)
PATJPATJ crumbs cell polarity complex component. (1360 aa)
PARD3Par-3 family cell polarity regulator. (1296 aa)
PARD6GPar-6 family cell polarity regulator gamma. (383 aa)
CTNNB1Catenin beta 1. (781 aa)
ActbActin beta. (375 aa)
LOC101977927Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
LOC101978211Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (220 aa)
Sh3bp1Uncharacterized protein. (678 aa)
STRNStriatin. (738 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (489 aa)
ADCYAP1R1ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (480 aa)
PRKCZNon-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (413 aa)
EPB41L4BErythrocyte membrane protein band 4.1 like 4B. (838 aa)
POF1BPOF1B actin binding protein. (590 aa)
Rab13Uncharacterized protein. (203 aa)
Tjp2Uncharacterized protein. (1138 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1738 aa)
TJAP1Tight junction associated protein 1. (540 aa)
PARD3BPar-3 family cell polarity regulator beta. (1204 aa)
CLDN10Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (231 aa)
ILDR1Immunoglobulin like domain containing receptor 1. (544 aa)
CLDN9Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (217 aa)
VAPAVAMP associated protein A. (222 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
PARD6BPar-6 family cell polarity regulator beta. (350 aa)
CRB1Crumbs cell polarity complex component 1. (1406 aa)
NECTIN2Nectin cell adhesion molecule 2. (534 aa)
CLDN16Claudin 16. (200 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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