(32 nodes) Calyx of Held network (Ictidomys tridecemlineatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PRKCG	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (697 aa)
	PRKCA	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
	Atp1a3	Sodium/potassium-transporting ATPase subunit alpha. (1021 aa)
	GIT2	GIT ArfGAP 2. (752 aa)
	Actg1	Uncharacterized protein. (375 aa)
	Tprg1l	HSac2 domain-containing protein. (266 aa)
	CALB1	Calbindin 1. (261 aa)
	KCNC4	Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family. (506 aa)
	KCNK2	Potassium two pore domain channel subfamily K member 2; Belongs to the two pore domain potassium channel (TC 1.A.1.8) family. (422 aa)
	PRKCB	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
	GIT1	GIT ArfGAP 1. (773 aa)
	Actb	Actin beta. (375 aa)
	GLRA1	Glycine receptor alpha 1; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (456 aa)
	UNC13C	Unc-13 homolog C. (2117 aa)
	LOC101954496	Uncharacterized protein. (346 aa)
	I3MYM1_ICTTR	Uncharacterized protein. (210 aa)
	ACTL8	Actin like 8; Belongs to the actin family. (366 aa)
	CPLX2	Complexin 2. (134 aa)
	ITSN1	Intersectin 1. (1655 aa)
	I3N998_ICTTR	Uncharacterized protein. (305 aa)
	KCNA2	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family. (499 aa)
	KCNA3	Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family. (495 aa)
	I3NCC6_ICTTR	Uncharacterized protein; Belongs to the actin family. (340 aa)
	KCNC1	Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family. (534 aa)
	NOS1	Nitric oxide synthase; Produces nitric oxide (NO). (1329 aa)
	Septin5	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (378 aa)
	TSPOAP1	TSPO associated protein 1. (1912 aa)
	ENSSTOP00000030397	Uncharacterized protein; Belongs to the actin family. (148 aa)
	ENSSTOP00000031475	Uncharacterized protein; Belongs to the actin family. (173 aa)
	UNC13B	Unc-13 homolog B. (1986 aa)
	KCNA1	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family. (476 aa)
	UNC13A	Unc-13 homolog A. (1732 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ACTL8	ITSN1	ENSSTOP00000018033	ENSSTOP00000020496	Actin like 8; Belongs to the actin family.	Intersectin 1.	0.632
Actb	ITSN1	ENSSTOP00000013257	ENSSTOP00000020496	Actin beta.	Intersectin 1.	0.632
Actg1	ITSN1	ENSSTOP00000006131	ENSSTOP00000020496	Uncharacterized protein.	Intersectin 1.	0.632
CALB1	KCNA1	ENSSTOP00000008214	ENSSTOP00000031966	Calbindin 1.	Potassium voltage-gated channel subfamily A member 1; Belongs to the potassium channel family.	0.457
CALB1	KCNA2	ENSSTOP00000008214	ENSSTOP00000021642	Calbindin 1.	Potassium voltage-gated channel subfamily A member 2; Belongs to the potassium channel family.	0.457
CALB1	KCNA3	ENSSTOP00000008214	ENSSTOP00000021907	Calbindin 1.	Potassium voltage-gated channel subfamily A member 3; Belongs to the potassium channel family.	0.411
CALB1	KCNC1	ENSSTOP00000008214	ENSSTOP00000022131	Calbindin 1.	Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family.	0.415
CALB1	NOS1	ENSSTOP00000008214	ENSSTOP00000023214	Calbindin 1.	Nitric oxide synthase; Produces nitric oxide (NO).	0.412
CPLX2	TSPOAP1	ENSSTOP00000019424	ENSSTOP00000030304	Complexin 2.	TSPO associated protein 1.	0.471
CPLX2	UNC13A	ENSSTOP00000019424	ENSSTOP00000032144	Complexin 2.	Unc-13 homolog A.	0.632
CPLX2	UNC13B	ENSSTOP00000019424	ENSSTOP00000031693	Complexin 2.	Unc-13 homolog B.	0.632
CPLX2	UNC13C	ENSSTOP00000019424	ENSSTOP00000015987	Complexin 2.	Unc-13 homolog C.	0.632
ENSSTOP00000030397	ITSN1	ENSSTOP00000030397	ENSSTOP00000020496	Uncharacterized protein; Belongs to the actin family.	Intersectin 1.	0.632
ENSSTOP00000031475	ITSN1	ENSSTOP00000031475	ENSSTOP00000020496	Uncharacterized protein; Belongs to the actin family.	Intersectin 1.	0.632
GIT1	GIT2	ENSSTOP00000012806	ENSSTOP00000004111	GIT ArfGAP 1.	GIT ArfGAP 2.	0.899
GIT1	ITSN1	ENSSTOP00000012806	ENSSTOP00000020496	GIT ArfGAP 1.	Intersectin 1.	0.728
GIT2	GIT1	ENSSTOP00000004111	ENSSTOP00000012806	GIT ArfGAP 2.	GIT ArfGAP 1.	0.899
GIT2	ITSN1	ENSSTOP00000004111	ENSSTOP00000020496	GIT ArfGAP 2.	Intersectin 1.	0.728
I3N998_ICTTR	KCNC1	ENSSTOP00000020944	ENSSTOP00000022131	Uncharacterized protein.	Potassium voltage-gated channel subfamily C member 1; Belongs to the potassium channel family.	0.497
I3N998_ICTTR	KCNC4	ENSSTOP00000020944	ENSSTOP00000008649	Uncharacterized protein.	Potassium voltage-gated channel subfamily C member 4; Belongs to the potassium channel family.	0.414