27 items (Ictidomys tridecemlineatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	BTK	Tyrosine-protein kinase. (659 aa)
	KIT	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (977 aa)
	PLA2G3	Phospholipase A2 group III. (626 aa)
	Rabgef1	Uncharacterized protein. (491 aa)
	ADORA2B	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (332 aa)
	NR4A3	Nuclear receptor subfamily 4 group A member 3. (630 aa)
	CBL	Cbl proto-oncogene. (870 aa)
	SYK	Tyrosine-protein kinase. (626 aa)
	SNAP23	Synaptosomal-associated protein; Belongs to the SNAP-25 family. (222 aa)
	CD48	CD48 molecule. (254 aa)
	GRP	Gastrin releasing peptide. (138 aa)
	CHGA	Chromogranin A. (432 aa)
	LCP2	Lymphocyte cytosolic protein 2. (533 aa)
	I3MSE5_ICTTR	Uncharacterized protein. (118 aa)
	CLNK	Cytokine dependent hematopoietic cell linker. (423 aa)
	NDRG1	N-myc downstream regulated 1. (394 aa)
	Ywhaz	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family. (245 aa)
	CPLX2	Complexin 2. (134 aa)
	RHOH	Ras homolog family member H. (190 aa)
	ADORA3	Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family. (319 aa)
	PTGDR	Prostaglandin D2 receptor. (355 aa)
	Rab44	Uncharacterized protein. (645 aa)
	LOC101965246	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
	LAT	Linker for activation of T cells. (234 aa)
	LYN	Tyrosine-protein kinase. (512 aa)
	ENSSTOP00000029855	Uncharacterized protein. (196 aa)
	RASGRP1	RAS guanyl releasing protein 1. (797 aa)

Your Current Organism:

Ictidomys tridecemlineatus

NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADORA2B	ADORA3	ENSSTOP00000003790	ENSSTOP00000021652	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	0.785
ADORA3	ADORA2B	ENSSTOP00000021652	ENSSTOP00000003790	Adenosine receptor A3; Receptor for adenosine. The activity of this receptor is mediated by G proteins which inhibit adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	Adenosine receptor A2; Receptor for adenosine. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. Belongs to the G-protein coupled receptor 1 family.	0.785
BTK	CBL	ENSSTOP00000004260	ENSSTOP00000004776	Tyrosine-protein kinase.	Cbl proto-oncogene.	0.792
BTK	CD48	ENSSTOP00000004260	ENSSTOP00000006473	Tyrosine-protein kinase.	CD48 molecule.	0.437
BTK	CLNK	ENSSTOP00000004260	ENSSTOP00000017748	Tyrosine-protein kinase.	Cytokine dependent hematopoietic cell linker.	0.455
BTK	GRP	ENSSTOP00000004260	ENSSTOP00000011755	Tyrosine-protein kinase.	Gastrin releasing peptide.	0.571
BTK	KIT	ENSSTOP00000004260	ENSSTOP00000000677	Tyrosine-protein kinase.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.590
BTK	LAT	ENSSTOP00000004260	ENSSTOP00000025910	Tyrosine-protein kinase.	Linker for activation of T cells.	0.680
BTK	LCP2	ENSSTOP00000004260	ENSSTOP00000014791	Tyrosine-protein kinase.	Lymphocyte cytosolic protein 2.	0.965
BTK	LOC101965246	ENSSTOP00000004260	ENSSTOP00000024176	Tyrosine-protein kinase.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.466
BTK	LYN	ENSSTOP00000004260	ENSSTOP00000029495	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.949
BTK	SYK	ENSSTOP00000004260	ENSSTOP00000005180	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.955
BTK	Ywhaz	ENSSTOP00000004260	ENSSTOP00000018402	Tyrosine-protein kinase.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta; Belongs to the 14-3-3 family.	0.466
CBL	BTK	ENSSTOP00000004776	ENSSTOP00000004260	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.792
CBL	CLNK	ENSSTOP00000004776	ENSSTOP00000017748	Cbl proto-oncogene.	Cytokine dependent hematopoietic cell linker.	0.703
CBL	KIT	ENSSTOP00000004776	ENSSTOP00000000677	Cbl proto-oncogene.	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.	0.878
CBL	LAT	ENSSTOP00000004776	ENSSTOP00000025910	Cbl proto-oncogene.	Linker for activation of T cells.	0.514
CBL	LCP2	ENSSTOP00000004776	ENSSTOP00000014791	Cbl proto-oncogene.	Lymphocyte cytosolic protein 2.	0.824
CBL	LOC101965246	ENSSTOP00000004776	ENSSTOP00000024176	Cbl proto-oncogene.	14_3_3 domain-containing protein; Belongs to the 14-3-3 family.	0.513
CBL	LYN	ENSSTOP00000004776	ENSSTOP00000029495	Cbl proto-oncogene.	Tyrosine-protein kinase.	0.975