STRINGSTRING
TBX3 TBX3 SOX8 SOX8 ANKRD2 ANKRD2 SOSTDC1 SOSTDC1 CMTM5 CMTM5 GDF3 GDF3 IL36G IL36G MSTN MSTN BMP4 BMP4 EID2B EID2B TNF TNF CCL17 CCL17 TMEM182 TMEM182 IL18 IL18 Ddit3 Ddit3 ID3 ID3 NMRK2 NMRK2 DLL1 DLL1 SRA1 SRA1 MKX MKX SOX9 SOX9 CXCL14 CXCL14 PPARD PPARD CXCL10 CXCL10 TGFB1 TGFB1 PRICKLE1 PRICKLE1 MBNL3 MBNL3 ENSSTOP00000032126 ENSSTOP00000032126
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX3T-box transcription factor 3. (744 aa)
SOX8SRY-box transcription factor 8. (466 aa)
ANKRD2Ankyrin repeat domain 2. (336 aa)
SOSTDC1Sclerostin domain containing 1. (206 aa)
CMTM5CKLF like MARVEL transmembrane domain containing 5. (156 aa)
GDF3Growth differentiation factor 3. (360 aa)
IL36GInterleukin-1. (161 aa)
MSTNMyostatin. (376 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
EID2BEP300 interacting inhibitor of differentiation 2B. (152 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
CCL17C-C motif chemokine ligand 17. (102 aa)
TMEM182Transmembrane protein 182. (229 aa)
IL18Interleukin-18; A proinflammatory cytokine primarily involved in polarized T- helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T- helper 1 (Th1) cells and natural killer (NK) cells. Belongs to the IL-1 family. (193 aa)
Ddit3DNA damage-inducible transcript 3 protein; Multifunctional transcription factor in ER stress response. Plays an essential role in the response to a wide variety of cell stresses and induces cell cycle arrest and apoptosis in response to ER stress. Plays a dual role both as an inhibitor of CCAAT/enhancer- binding protein (C/EBP) function and as an activator of other genes. Acts as a dominant-negative regulator of C/EBP-induced transcription: dimerizes with members of the C/EBP family, impairs their association with C/EBP binding sites in the promoter regions, and inhibits the expression [...] (168 aa)
ID3Inhibitor of DNA binding 3, HLH protein. (119 aa)
NMRK2Nicotinamide riboside kinase 2. (196 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (715 aa)
SRA1Steroid receptor RNA activator 1. (235 aa)
MKXMohawk homeobox. (352 aa)
SOX9SRY-box transcription factor 9. (509 aa)
CXCL14C-X-C motif chemokine ligand 14. (99 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
CXCL10C-X-C motif chemokine. (98 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (390 aa)
PRICKLE1Prickle planar cell polarity protein 1. (833 aa)
MBNL3Muscleblind like splicing regulator 3. (357 aa)
ENSSTOP00000032126Uncharacterized protein. (141 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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