STRINGSTRING
Mag Mag GPR37L1 GPR37L1 WDR62 WDR62 DISP3 DISP3 EDNRB EDNRB ATOH1 ATOH1 APBB1 APBB1 ASPM ASPM DUOXA1 DUOXA1 EFNA3 EFNA3 CALR CALR SOX8 SOX8 CTDSP1 CTDSP1 LTK LTK Rest Rest LRRC45 LRRC45 RAC1 RAC1 MIB1 MIB1 ETV5 ETV5 LBX1 LBX1 LOC101973389 LOC101973389 KDM4C KDM4C GATA2 GATA2 DAB1 DAB1 ISL2 ISL2 CXCL12 CXCL12 TIAM1 TIAM1 BRINP1 BRINP1 EYA1 EYA1 LMX1A LMX1A MYCL MYCL I3M4W8_ICTTR I3M4W8_ICTTR GLI2 GLI2 CNTN2 CNTN2 NKX2-5 NKX2-5 Ttc3 Ttc3 Lin28a Lin28a FEZ1 FEZ1 DPYSL2 DPYSL2 CDON CDON MAPK8IP3 MAPK8IP3 NOTCH3 NOTCH3 FMR1 FMR1 RARA RARA ENSSTOP00000026011 ENSSTOP00000026011 PBX1 PBX1 FGFR1 FGFR1 JAG1 JAG1 PTBP1 PTBP1 LOC101978074 LOC101978074 APP APP EIF4G1 EIF4G1 CPNE1 CPNE1 TFAP2A TFAP2A MEF2C MEF2C BCL11A BCL11A SPAG9 SPAG9 MEIS1 MEIS1 BRINP3 BRINP3 MMD MMD GDPD5 GDPD5 TUNAR TUNAR MAP3K13 MAP3K13 BNIP2 BNIP2 NLGN1 NLGN1 Tcf12 Tcf12 TCF4 TCF4 PROX1 PROX1 ENSSTOP00000027359 ENSSTOP00000027359 SOX5 SOX5 B2M B2M NF1 NF1 LOC101968601 LOC101968601 TBX6 TBX6 NR2E1 NR2E1 BIN1 BIN1 MTOR MTOR NREP NREP LOC101974830 LOC101974830 NCOA1 NCOA1 PRPF19 PRPF19 ENSSTOP00000031278 ENSSTOP00000031278 Numb Numb VWC2L VWC2L CASZ1 CASZ1 ZC4H2 ZC4H2 ADRA2B ADRA2B ZHX2 ZHX2 BCL2 BCL2 I3MVL6_ICTTR I3MVL6_ICTTR SFRP1 SFRP1 Ect2 Ect2 VWC2 VWC2 KCTD11 KCTD11 BEND6 BEND6 LOC101970905 LOC101970905 BMP6 BMP6 MED1 MED1 I3N013_ICTTR I3N013_ICTTR I3N090_ICTTR I3N090_ICTTR Dmd Dmd SIX1 SIX1 NTF3 NTF3 HEY2 HEY2 DLL1 DLL1 Hspa1b Hspa1b LOC101960206 LOC101960206 DLX2 DLX2 GDF6 GDF6 BMP2 BMP2 GDF7 GDF7 NEUROG3 NEUROG3 FOXG1 FOXG1 ATN1 ATN1 NEUROG1 NEUROG1 MMD2 MMD2 NEUROD2 NEUROD2 CCR5 CCR5 ROCK1 ROCK1 NEUROD1 NEUROD1 LOC101955349 LOC101955349 PHOX2B PHOX2B HES1 HES1 FOXA2 FOXA2 FEZF1 FEZF1 SIX3 SIX3 NEUROG2 NEUROG2 SOX9 SOX9 FERD3L FERD3L FEZF2 FEZF2 POU4F2 POU4F2 WNT3A WNT3A CRX CRX Kdm4a Kdm4a ASCL1 ASCL1 HES5 HES5 ID2 ID2 Foxo3 Foxo3 TP73 TP73 HEY1 HEY1 GDF5 GDF5 SALL1 SALL1 BCL11B BCL11B HMG20B HMG20B Ntf4 Ntf4 ZFHX3 ZFHX3 GLI3 GLI3 GSK3B GSK3B GPRC5B GPRC5B DICER1 DICER1 GDF11 GDF11 PCP4 PCP4 BCL6 BCL6 PTGER3 PTGER3 TRPC5 TRPC5 ENSSTOP00000025794 ENSSTOP00000025794 TRIM32 TRIM32 CNTN4 CNTN4 FGF20 FGF20 RNF112 RNF112 RTN4 RTN4 LRRK2 LRRK2 ARHGEF2 ARHGEF2 GRIP2 GRIP2 BMP4 BMP4 RET RET NEPRO NEPRO EIF4E EIF4E MAP1B MAP1B SFRP2 SFRP2 ZFHX2 ZFHX2 ALK ALK TRPC6 TRPC6 PAX6 PAX6 S1PR5 S1PR5 Fgf2 Fgf2 PTEN PTEN IMPACT IMPACT CAV1 CAV1 NAP1L2 NAP1L2 SIN3A SIN3A DLX6 DLX6 CNTF CNTF SHH SHH LSM1 LSM1 FOXA1 FOXA1 IRX3 IRX3 TGIF1 TGIF1 ZEB1 ZEB1 HOXA2 HOXA2 NBL1 NBL1 EIF2AK4 EIF2AK4 NBN NBN HOXD3 HOXD3 LOC101955529 LOC101955529 DDX6 DDX6 ESRP1 ESRP1 EIF4ENIF1 EIF4ENIF1 YWHAG YWHAG RAC3 RAC3 HMG20A HMG20A EPO EPO DKK1 DKK1 ITGB1 ITGB1 ISL1 ISL1 ZNF536 ZNF536 Hspa1a Hspa1a CDK5RAP2 CDK5RAP2 DLX1 DLX1 SH3GL3 SH3GL3 BMP7 BMP7 MAPK8 MAPK8 CRADD CRADD SOCS2 SOCS2 Mycn Mycn OPA1 OPA1 BRINP2 BRINP2 ACTR3 ACTR3 DIXDC1 DIXDC1 HES3 HES3 HEYL HEYL TCF3 TCF3 RAP1GAP RAP1GAP
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MagUncharacterized protein. (64 aa)
GPR37L1G protein-coupled receptor 37 like 1. (480 aa)
WDR62WD repeat domain 62. (1517 aa)
DISP3Dispatched RND transporter family member 3. (1244 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (443 aa)
ATOH1Atonal bHLH transcription factor 1. (352 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (708 aa)
ASPMAbnormal spindle microtubule assembly. (3203 aa)
DUOXA1Dual oxidase maturation factor 1. (342 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (210 aa)
CALRCalreticulin. (418 aa)
SOX8SRY-box transcription factor 8. (466 aa)
CTDSP1CTD small phosphatase 1. (238 aa)
LTKTyrosine-protein kinase receptor. (576 aa)
RestUncharacterized protein. (328 aa)
LRRC45Leucine rich repeat containing 45. (670 aa)
RAC1Rac family small GTPase 1. (211 aa)
MIB1Mindbomb E3 ubiquitin protein ligase 1. (1006 aa)
ETV5ETS variant 5. (510 aa)
LBX1Ladybird homeobox 1. (281 aa)
LOC101973389Uncharacterized protein. (182 aa)
KDM4CLysine demethylase 4C. (1050 aa)
GATA2GATA binding protein 2. (481 aa)
DAB1DAB adaptor protein 1. (555 aa)
ISL2ISL LIM homeobox 2. (359 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (119 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1567 aa)
BRINP1BMP/retinoic acid inducible neural specific 1. (761 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (592 aa)
LMX1ALIM homeobox transcription factor 1 alpha. (382 aa)
MYCLMYCL proto-oncogene, bHLH transcription factor. (364 aa)
I3M4W8_ICTTRUncharacterized protein. (207 aa)
GLI2GLI family zinc finger 2. (1540 aa)
CNTN2Contactin 2. (1045 aa)
NKX2-5NK2 homeobox 5. (321 aa)
Ttc3Uncharacterized protein. (1070 aa)
Lin28aCCHC-type domain-containing protein. (210 aa)
FEZ1Fasciculation and elongation protein zeta 1. (219 aa)
DPYSL2Dihydropyrimidinase like 2. (677 aa)
CDONCell adhesion associated, oncogene regulated. (1264 aa)
MAPK8IP3Mitogen-activated protein kinase 8 interacting protein 3. (1337 aa)
NOTCH3Notch receptor 3. (2277 aa)
FMR1Fragile X mental retardation 1. (631 aa)
RARARetinoic acid receptor alpha. (462 aa)
ENSSTOP00000026011BHLH domain-containing protein. (102 aa)
PBX1PBX homeobox 1. (430 aa)
FGFR1Fibroblast growth factor receptor. (822 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1218 aa)
PTBP1Polypyrimidine tract binding protein 1. (557 aa)
LOC101978074Uncharacterized protein. (148 aa)
APPAmyloid beta precursor protein. (739 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1611 aa)
CPNE1Copine 1. (537 aa)
TFAP2ATranscription factor AP-2 alpha. (477 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
BCL11ABAF chromatin remodeling complex subunit BCL11A. (834 aa)
SPAG9Sperm associated antigen 9. (1329 aa)
MEIS1Meis homeobox 1. (465 aa)
BRINP3BMP/retinoic acid inducible neural specific 3. (766 aa)
MMDMonocyte to macrophage differentiation associated. (238 aa)
GDPD5Glycerophosphodiester phosphodiesterase domain containing 5. (610 aa)
TUNARTCL1 upstream neural differentiation-associated RNA. (61 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase 13; Activates the JUN N-terminal pathway through activation of the MAP kinase kinase MAP2K7. (966 aa)
BNIP2BCL2 interacting protein 2. (333 aa)
NLGN1Neuroligin 1. (843 aa)
Tcf12BHLH domain-containing protein. (706 aa)
TCF4Transcription factor 4. (671 aa)
PROX1Prospero homeobox 1. (737 aa)
ENSSTOP00000027359PID domain-containing protein. (588 aa)
SOX5SRY-box transcription factor 5. (763 aa)
B2MBeta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. (123 aa)
NF1Neurofibromin 1. (2473 aa)
LOC101968601Uncharacterized protein. (80 aa)
TBX6T-box transcription factor 6. (436 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
BIN1Bridging integrator 1. (609 aa)
MTORSerine/threonine-protein kinase mTOR; Belongs to the PI3/PI4-kinase family. (2577 aa)
NREPNeuronal regeneration related protein. (68 aa)
LOC101974830BHLH domain-containing protein. (460 aa)
NCOA1Nuclear receptor coactivator. (1442 aa)
PRPF19Pre-mRNA processing factor 19. (512 aa)
ENSSTOP00000031278CSP domain-containing protein. (186 aa)
NumbPID domain-containing protein. (653 aa)
VWC2LVon Willebrand factor C domain containing 2 like. (222 aa)
CASZ1Castor zinc finger 1. (1720 aa)
ZC4H2Zinc finger C4H2-type containing. (224 aa)
ADRA2BAdrenoceptor alpha 2B. (449 aa)
ZHX2Zinc fingers and homeoboxes 2. (837 aa)
BCL2BCL2 apoptosis regulator. (195 aa)
I3MVL6_ICTTRUncharacterized protein. (192 aa)
SFRP1Secreted frizzled related protein 1. (314 aa)
Ect2Uncharacterized protein. (188 aa)
VWC2Von Willebrand factor C domain containing 2. (325 aa)
KCTD11Potassium channel tetramerization domain containing 11. (232 aa)
BEND6BEN domain containing 6. (281 aa)
LOC101970905NGF domain-containing protein; Belongs to the NGF-beta family. (210 aa)
BMP6Bone morphogenetic protein 6. (507 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1575 aa)
I3N013_ICTTRUncharacterized protein. (141 aa)
I3N090_ICTTRUncharacterized protein. (207 aa)
DmdUncharacterized protein. (1255 aa)
SIX1SIX homeobox 1. (284 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (270 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (337 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (715 aa)
Hspa1bHeat shock protein family A (Hsp70) member 1B. (641 aa)
LOC101960206Uncharacterized protein. (207 aa)
DLX2Distal-less homeobox 2. (329 aa)
GDF6Growth differentiation factor 6. (460 aa)
BMP2Bone morphogenetic protein 2. (395 aa)
GDF7Growth differentiation factor 7. (445 aa)
NEUROG3Neurogenin 3. (215 aa)
FOXG1Forkhead box G1. (428 aa)
ATN1Atrophin 1. (1191 aa)
NEUROG1Neurogenin 1. (244 aa)
MMD2Monocyte to macrophage differentiation associated 2. (230 aa)
NEUROD2Neurogenic differentiation factor. (382 aa)
CCR5C-C motif chemokine receptor 5 (gene/pseudogene); Belongs to the G-protein coupled receptor 1 family. (351 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
NEUROD1Neurogenic differentiation factor. (356 aa)
LOC101955349BHLH domain-containing protein. (454 aa)
PHOX2BPaired like homeobox 2B. (252 aa)
HES1Hes family bHLH transcription factor 1. (280 aa)
FOXA2Forkhead box A2. (463 aa)
FEZF1FEZ family zinc finger 1. (475 aa)
SIX3SIX homeobox 3. (275 aa)
NEUROG2Neurogenin 2. (271 aa)
SOX9SRY-box transcription factor 9. (509 aa)
FERD3LFer3 like bHLH transcription factor. (168 aa)
FEZF2FEZ family zinc finger 2. (457 aa)
POU4F2POU domain protein. (410 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (352 aa)
CRXCone-rod homeobox. (299 aa)
Kdm4aUncharacterized protein. (1064 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (234 aa)
HES5Hes family bHLH transcription factor 5. (141 aa)
ID2Inhibitor of DNA binding 2. (134 aa)
Foxo3Forkhead box O3. (673 aa)
TP73Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein. (634 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
GDF5Growth differentiation factor 5. (495 aa)
SALL1Spalt like transcription factor 1. (1313 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (894 aa)
HMG20BHigh mobility group 20B. (317 aa)
Ntf4NGF domain-containing protein; Belongs to the NGF-beta family. (210 aa)
ZFHX3Zinc finger homeobox 3. (3696 aa)
GLI3GLI family zinc finger 3. (1582 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa)
GPRC5BG protein-coupled receptor class C group 5 member B. (411 aa)
DICER1Dicer 1, ribonuclease III; Belongs to the helicase family. Dicer subfamily. (1904 aa)
GDF11Growth differentiation factor 11. (387 aa)
PCP4Purkinje cell protein 4. (62 aa)
BCL6BCL6 transcription repressor. (706 aa)
PTGER3Prostaglandin E receptor 3. (388 aa)
TRPC5Transient receptor potential cation channel subfamily C member 5; Belongs to the transient receptor (TC 1.A.4) family. (974 aa)
ENSSTOP00000025794Uncharacterized protein. (78 aa)
TRIM32Tripartite motif containing 32. (658 aa)
CNTN4Contactin 4. (1027 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (211 aa)
RNF112Ring finger protein 112. (645 aa)
RTN4Reticulon. (1177 aa)
LRRK2Leucine rich repeat kinase 2. (2520 aa)
ARHGEF2Rho/Rac guanine nucleotide exchange factor 2. (869 aa)
GRIP2Glutamate receptor interacting protein 2. (949 aa)
BMP4Bone morphogenetic protein 4. (409 aa)
RETProto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1112 aa)
NEPRONucleolus and neural progenitor protein. (560 aa)
EIF4EEukaryotic translation initiation factor 4E; Belongs to the eukaryotic initiation factor 4E family. (218 aa)
MAP1BMicrotubule associated protein 1B. (2469 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
ZFHX2Zinc finger homeobox 2. (2567 aa)
ALKTyrosine-protein kinase receptor. (1612 aa)
TRPC6Transient receptor potential cation channel subfamily C member 6; Belongs to the transient receptor (TC 1.A.4) family. (903 aa)
PAX6Paired box 6. (436 aa)
S1PR5Sphingosine-1-phosphate receptor 5; Belongs to the G-protein coupled receptor 1 family. (398 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (144 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (403 aa)
IMPACTImpact RWD domain protein. (297 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
NAP1L2Nucleosome assembly protein 1 like 2; Belongs to the nucleosome assembly protein (NAP) family. (458 aa)
SIN3ASIN3 transcription regulator family member A. (1274 aa)
DLX6Distal-less homeobox 6. (175 aa)
CNTFCiliary neurotrophic factor. (199 aa)
SHHSonic hedgehog signaling molecule. (370 aa)
LSM1U6 snRNA-associated Sm-like protein LSm1; Plays a role in the degradation of histone mRNAs, the only eukaryotic mRNAs that are not polyadenylated. Probably also part of an LSm subunits-containing complex involved in the general process of mRNA degradation. (82 aa)
FOXA1Forkhead box A1. (468 aa)
IRX3Iroquois homeobox 3. (443 aa)
TGIF1TGFB induced factor homeobox 1. (272 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1123 aa)
HOXA2Homeobox A2. (374 aa)
NBL1NBL1, DAN family BMP antagonist. (180 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1631 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (634 aa)
HOXD3Homeobox D3. (432 aa)
LOC101955529Uncharacterized protein. (111 aa)
DDX6DEAD-box helicase 6; Belongs to the DEAD box helicase family. (483 aa)
ESRP1Epithelial splicing regulatory protein 1. (682 aa)
EIF4ENIF1Eukaryotic translation initiation factor 4E nuclear import factor 1. (967 aa)
YWHAGTyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
RAC3Rac family small GTPase 3. (185 aa)
HMG20AHigh mobility group 20A. (347 aa)
EPOErythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. Belongs to the EPO/TPO family. (192 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (268 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ZNF536Zinc finger protein 536. (1298 aa)
Hspa1aUncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
CDK5RAP2CDK5 regulatory subunit associated protein 2. (1860 aa)
DLX1Distal-less homeobox 1. (255 aa)
SH3GL3SH3 domain containing GRB2 like 3, endophilin A3. (346 aa)
BMP7Bone morphogenetic protein 7. (431 aa)
MAPK8Mitogen-activated protein kinase. (427 aa)
CRADDCASP2 and RIPK1 domain containing adaptor with death domain. (199 aa)
SOCS2Suppressor of cytokine signaling 2. (159 aa)
MycnBHLH domain-containing protein. (460 aa)
OPA1OPA1 mitochondrial dynamin like GTPase; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (947 aa)
BRINP2BMP/retinoic acid inducible neural specific 2. (782 aa)
ACTR3Actin related protein 3; Belongs to the actin family. (418 aa)
DIXDC1DIX domain containing 1. (705 aa)
HES3Hes family bHLH transcription factor 3. (178 aa)
HEYLHes related family bHLH transcription factor with YRPW motif like. (321 aa)
TCF3Transcription factor 3. (681 aa)
RAP1GAPRAP1 GTPase activating protein. (728 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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