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| | CUL4B | Cullin 4B; Belongs to the cullin family. (970 aa) |
| | FBXW7 | F-box and WD repeat domain containing 7. (713 aa) |
| | Ecscr | Uncharacterized protein. (239 aa) |
| | FBXL5 | F-box and leucine rich repeat protein 5. (667 aa) |
| | HSPBP1 | HSPA (Hsp70) binding protein 1. (211 aa) |
| | TRIM32 | Tripartite motif containing 32. (658 aa) |
| | ARIH1 | RBR-type E3 ubiquitin transferase. (555 aa) |
| | TRIB1 | Tribbles pseudokinase 1. (372 aa) |
| | I3MUV0_ICTTR | ANK_REP_REGION domain-containing protein. (283 aa) |
| | CHFR | Checkpoint with forkhead and ring finger domains. (724 aa) |
| | SMAD7 | Mothers against decapentaplegic homolog. (426 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | GABARAP | GABA type A receptor-associated protein. (117 aa) |
| | STUB1 | STIP1 homology and U-box containing protein 1. (303 aa) |
| | CDKN1B | Cyclin dependent kinase inhibitor 1B. (198 aa) |
| | TNFRSF1B | TNF receptor superfamily member 1B. (436 aa) |
| | RNFT1 | Ring finger protein, transmembrane 1. (398 aa) |
| | USP5 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (858 aa) |
| | Rbx1 | RING-type domain-containing protein. (108 aa) |
| | RNFT2 | Ring finger protein, transmembrane 2. (425 aa) |
| | FMR1 | Fragile X mental retardation 1. (631 aa) |
| | RNF41 | Ring finger protein 41. (317 aa) |
| | SH3RF3 | SH3 domain containing ring finger 3. (757 aa) |
| | SORL1 | Sortilin related receptor 1. (2199 aa) |
| | RDX | Radixin. (583 aa) |
| | PSMD10 | ANK_REP_REGION domain-containing protein. (226 aa) |
| | NUPR1 | Nuclear protein 1, transcriptional regulator. (81 aa) |
| | STX5 | Syntaxin 5. (400 aa) |
| | RNF19B | RBR-type E3 ubiquitin transferase. (631 aa) |
| | TMTC3 | Transmembrane O-mannosyltransferase targeting cadherins 3. (917 aa) |
| | RNF40 | E3 ubiquitin protein ligase; Belongs to the BRE1 family. (1001 aa) |
| | Ndfip1 | Nedd4 family interacting protein 1. (229 aa) |
| | PSMC2 | Proteasome 26S subunit, ATPase 2; Belongs to the AAA ATPase family. (465 aa) |
| | LOC101967743 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (416 aa) |
| | PCSK9 | Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (682 aa) |
| | RNF19A | RBR-type E3 ubiquitin transferase. (838 aa) |
| | DDA1 | DET1 and DDB1 associated 1. (102 aa) |
| | VCP | Valosin containing protein; Belongs to the AAA ATPase family. (806 aa) |
| | FBXW8 | F-box and WD repeat domain containing 8. (492 aa) |
| | ITCH | E3 ubiquitin-protein ligase. (855 aa) |
| | ATG4B | Cysteine protease; Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy; Belongs to the peptidase C54 family. (393 aa) |
| | Mdm2 | E3 ubiquitin-protein ligase Mdm2; Belongs to the MDM2/MDM4 family. (489 aa) |
| | CLUL1 | Clusterin; Belongs to the clusterin family. (516 aa) |
| | Psmc6 | 26S proteasome regulatory subunit 10B; The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex. (389 aa) |
| | SH3RF1 | SH3 domain containing ring finger 1. (895 aa) |
| | AMER1 | APC membrane recruitment protein 1. (1136 aa) |
| | GGA1 | Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (636 aa) |
| | UBQLN2 | Ubiquilin 2. (627 aa) |
| | ABCA2 | ATP binding cassette subfamily A member 2. (2414 aa) |
| | DTL | Denticleless E3 ubiquitin protein ligase homolog. (730 aa) |
| | LRP1 | LDL receptor related protein 1. (4508 aa) |
| | SGTA | Small glutamine rich tetratricopeptide repeat containing alpha. (313 aa) |
| | Hspa1a | Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa) |
| | DVL1 | Dishevelled segment polarity protein 1. (696 aa) |
| | TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa) |
| | PLK3 | Serine/threonine-protein kinase PLK. (646 aa) |
| | DDRGK1 | DDRGK domain containing 1. (306 aa) |
| | C4BPA | Complement component 4 binding protein alpha. (540 aa) |
| | FBXW9 | F-box and WD repeat domain containing 9. (462 aa) |
| | TMEM259 | Transmembrane protein 259. (572 aa) |
| | RACK1 | Receptor for activated C kinase 1. (317 aa) |
| | PACSIN3 | Protein kinase C and casein kinase substrate in neurons 3. (424 aa) |
| | DDB1 | Damage specific DNA binding protein 1. (1140 aa) |
| | VIP | Vasoactive intestinal peptide. (170 aa) |
| | TNFAIP3 | TNF alpha induced protein 3. (776 aa) |
| | LDLR | Low density lipoprotein receptor. (863 aa) |
| | ZYG11B | Zyg-11 family member B, cell cycle regulator. (744 aa) |
| | MYLIP | Myosin regulatory light chain interacting protein. (437 aa) |
| | MAPK8 | Mitogen-activated protein kinase. (427 aa) |
| | PSMC4 | Proteasome 26S subunit, ATPase 4; Belongs to the AAA ATPase family. (418 aa) |
| | SNX33 | Sorting nexin. (573 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (601 aa) |
| | AXIN1 | Axin 1. (869 aa) |
| | RNF180 | Ring finger protein 180. (592 aa) |
| | CBLB | Cbl proto-oncogene B. (985 aa) |
| | Aurka | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (363 aa) |
| | PSMC3 | Proteasome 26S subunit, ATPase 3; Belongs to the AAA ATPase family. (446 aa) |
| | BAG2 | BCL2 associated athanogene 2. (211 aa) |
| | SNX9 | Sorting nexin. (610 aa) |
| | MKRN2 | Makorin ring finger protein 2. (415 aa) |
| | TREM2 | Triggering receptor expressed on myeloid cells 2. (262 aa) |
| | GPC3 | Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (579 aa) |
| | CDC20 | Cell division cycle 20. (499 aa) |
| | Foxo1 | Forkhead box protein O1; Transcription factor that is the main target of insulin signaling and regulates metabolic homeostasis in response to oxidative stress. Binds to the insulin response element (IRE) with consensus sequence 5'-TT[G/A]TTTTG-3' and the related Daf-16 family binding element (DBE) with consensus sequence 5'-TT[G/A]TTTAC-3'. Activity suppressed by insulin. Main regulator of redox balance and osteoblast numbers and controls bone mass. Orchestrates the endocrine function of the skeleton in regulating glucose metabolism. Acts synergistically with ATF4 to suppress osteocalc [...] (535 aa) |
| | SH3D19 | SH3 domain containing 19. (938 aa) |
| | HERPUD1 | Homocysteine inducible ER protein with ubiquitin like domain 1. (390 aa) |
| | ZER1 | Zyg-11 related cell cycle regulator. (776 aa) |
| | Psmc5 | AAA domain-containing protein; Belongs to the AAA ATPase family. (406 aa) |
| | GBA | Glucosylceramidase. (516 aa) |
| | Csnk2a1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (391 aa) |
| | TRIB3 | Tribbles pseudokinase 3. (363 aa) |
| | COP1 | COP1 E3 ubiquitin ligase. (641 aa) |
| | NUB1 | Negative regulator of ubiquitin like proteins 1. (612 aa) |
| | MARCHF2 | Membrane associated ring-CH-type finger 2. (246 aa) |
| | ENSSTOP00000031690 | ANK_REP_REGION domain-containing protein. (189 aa) |
| | APC | APC regulator of WNT signaling pathway. (2865 aa) |
| | LPCAT1 | Lysophosphatidylcholine acyltransferase 1. (522 aa) |
| | CLU | Clusterin; Functions as extracellular chaperone that prevents aggregation of non native proteins. Prevents stress-induced aggregation of blood plasma proteins. (448 aa) |
| | PIAS1 | Protein inhibitor of activated STAT 1. (651 aa) |
| | CSNK1A1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (353 aa) |
| | MAPK9 | Mitogen-activated protein kinase. (424 aa) |
| | SH3RF2 | SH3 domain containing ring finger 2. (730 aa) |
| | RGMA | Repulsive guidance molecule BMP co-receptor a. (450 aa) |
| | TNFSF12 | TNF superfamily member 12; Belongs to the tumor necrosis factor family. (249 aa) |
| | ASB11 | Ankyrin repeat and SOCS box containing 11. (323 aa) |
| | DAB2 | DAB adaptor protein 2. (767 aa) |
| | Sumo1 | Small ubiquitin-related modifier 1; Ubiquitin-like protein that can be covalently attached to proteins as a monomer or a lysine-linked polymer. Covalent attachment via an isopeptide bond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and linkage to the E2 enzyme UBE2I, and can be promoted by E3 ligases such as PIAS1-4, RANBP2 or CBX4. This post- translational modification on lysine residues of proteins plays a crucial role in a number of cellular processes such as nuclear transport, DNA replication and repair, mitosis and signal transduction. Involved for insta [...] (101 aa) |
| | Psmc1 | AAA domain-containing protein; Belongs to the AAA ATPase family. (440 aa) |
| | MAPK15 | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (554 aa) |
| | NSF | N-ethylmaleimide sensitive factor, vesicle fusing ATPase. (744 aa) |
| | SEC22B | SEC22 homolog B, vesicle trafficking protein (gene/pseudogene); Belongs to the synaptobrevin family. (215 aa) |
| | IER3 | Immediate early response 3. (157 aa) |
| | NKD2 | NKD inhibitor of WNT signaling pathway 2. (428 aa) |
| | ADAM8 | ADAM metallopeptidase domain 8. (818 aa) |
| | PLK2 | Serine/threonine-protein kinase PLK. (683 aa) |
| | RHBDD1 | Rhomboid domain containing 1. (313 aa) |
| | CD81 | Tetraspanin. (214 aa) |
| | LRRK2 | Leucine rich repeat kinase 2. (2520 aa) |
| | ANKIB1 | RBR-type E3 ubiquitin transferase. (617 aa) |
| | GSK3A | Glycogen synthase kinase 3 alpha; Belongs to the protein kinase superfamily. (395 aa) |
| | BAG6 | BCL2 associated athanogene 6. (1162 aa) |
| | GPLD1 | Glycosylphosphatidylinositol specific phospholipase D1. (896 aa) |
| | PSEN2 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (448 aa) |
| | LOC101972090 | AAA domain-containing protein; Belongs to the AAA ATPase family. (372 aa) |
| | ENSSTOP00000025090 | UBIQUITIN_CONJUGAT_2 domain-containing protein. (125 aa) |
| | CDC20B | Cell division cycle 20B. (523 aa) |
| | PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (467 aa) |
| | IL33 | Interleukin 33. (264 aa) |
| | SNF8 | Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa) |
| | NEDD4 | E3 ubiquitin-protein ligase. (901 aa) |
| | NRDC | Nardilysin convertase. (1231 aa) |
| | SIRT6 | Sirtuin 6. (351 aa) |
| | ATG7 | Ubiquitin-like modifier-activating enzyme ATG7; E1-like activating enzyme involved in the 2 ubiquitin-like systems required for cytoplasm to vacuole transport (Cvt) and autophagy. Activates ATG12 for its conjugation with ATG5 as well as the ATG8 family proteins for their conjugation with phosphatidylethanolamine. Both systems are needed for the ATG8 association to Cvt vesicles and autophagosomes membranes. Required for autophagic death induced by caspase-8 inhibition. Required for mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria [...] (726 aa) |
| | ENSSTOP00000026345 | Protein kinase domain-containing protein. (386 aa) |
| | ENSSTOP00000026420 | Uncharacterized protein. (465 aa) |
| | TMEM67 | Transmembrane protein 67. (999 aa) |
| | PRICKLE1 | Prickle planar cell polarity protein 1. (833 aa) |
| | APC2 | APC regulator of WNT signaling pathway 2. (2114 aa) |
| | RILP | Rab interacting lysosomal protein. (368 aa) |
| | GGA3 | Golgi associated, gamma adaptin ear containing, ARF binding protein 3. (728 aa) |
| | DNAJB2 | DnaJ heat shock protein family (Hsp40) member B2. (278 aa) |
| | ENSSTOP00000028027 | Protein kinase domain-containing protein. (300 aa) |
| | FZR1 | Fizzy and cell division cycle 20 related 1. (493 aa) |
| | OAZ3 | Ornithine decarboxylase antizyme 3. (230 aa) |
| | AKT1 | Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa) |
| | ENSSTOP00000028717 | RING-type domain-containing protein. (95 aa) |
| | SNX1 | Sorting nexin 1. (529 aa) |
| | RCHY1 | Ring finger and CHY zinc finger domain containing 1. (261 aa) |
| | GCLC | Glutamate-cysteine ligase catalytic subunit. (636 aa) |
| | RHBDD3 | Rhomboid domain containing 3. (392 aa) |
| | RNF144B | RBR-type E3 ubiquitin transferase. (303 aa) |
| | OSBPL7 | Oxysterol-binding protein; Belongs to the OSBP family. (920 aa) |
| | CSNK1D | Casein kinase 1 delta. (389 aa) |
| | ARIH2 | RBR-type E3 ubiquitin transferase. (493 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa) |
| | USP13 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (863 aa) |
| | Trib2 | Protein kinase domain-containing protein. (343 aa) |
| | SGSM3 | Small G protein signaling modulator 3. (750 aa) |
| | KLHL40 | Kelch like family member 40. (623 aa) |
| | FBXO22 | F-box protein 22. (404 aa) |
| | RNF144A | RBR-type E3 ubiquitin transferase. (292 aa) |
| | DACT1 | Dishevelled binding antagonist of beta catenin 1. (821 aa) |
| | OAZ2 | Uncharacterized protein. (189 aa) |
| | ASB9 | Ankyrin repeat and SOCS box containing 9. (265 aa) |
| | GSK3B | Glycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (433 aa) |
| | VPS28 | Vacuolar protein sorting-associated protein 28 homolog; Component of the ESCRT-I complex (endosomal sorting complex required for transport I), a regulator of vesicular trafficking process. (218 aa) |
| | NKD1 | NKD inhibitor of WNT signaling pathway 1. (444 aa) |
| | KCNE2 | Potassium voltage-gated channel subfamily E regulatory subunit 2. (122 aa) |
| | RNF185 | Ring finger protein 185. (192 aa) |
| | SOX17 | SRY-box transcription factor 17. (415 aa) |
| | RAB7A | RAB7A, member RAS oncogene family. (207 aa) |
| | UBE2V2 | Ubiquitin conjugating enzyme E2 V2. (145 aa) |
| | NDUFA13 | NADH:ubiquinone oxidoreductase subunit A13. (144 aa) |
| | SOCS5 | Suppressor of cytokine signaling 5. (536 aa) |
| | ADAM9 | ADAM metallopeptidase domain 9. (782 aa) |
| | SOX9 | SRY-box transcription factor 9. (509 aa) |
| | SIRT2 | NAD-dependent protein deacetylase; NAD-dependent protein deacetylase. (389 aa) |
| | NOP53 | Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (477 aa) |
| | WNT5A | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa) |
| | RAD23A | RAD23 homolog A, nucleotide excision repair protein. (362 aa) |
| | AXIN2 | Axin 2. (840 aa) |
| | Det1 | Uncharacterized protein. (550 aa) |
| | FAM122A | Family with sequence similarity 122A. (283 aa) |
| | ASB5 | Ankyrin repeat and SOCS box containing 5. (329 aa) |
| | DAB2IP | DAB2 interacting protein. (1148 aa) |
| | TIPARP | TCDD inducible poly(ADP-ribose) polymerase. (681 aa) |
| | CBFA2T3 | CBFA2/RUNX1 partner transcriptional co-repressor 3. (616 aa) |
| | Hspa1b | Heat shock protein family A (Hsp70) member 1B. (641 aa) |
| | I3N110_ICTTR | RING-type domain-containing protein. (147 aa) |
| | ZYG11A | Zyg-11 family member A, cell cycle regulator. (741 aa) |
| | Oaz1 | Uncharacterized protein. (178 aa) |
| | BBS7 | Bardet-Biedl syndrome 7. (703 aa) |
| | ENSSTOP00000029572 | Uncharacterized protein. (198 aa) |
| | ENSSTOP00000029812 | Small ubiquitin-related modifier. (112 aa) |
| | ENSSTOP00000030001 | AAA domain-containing protein. (334 aa) |
| | VGLL4 | Vestigial like family member 4. (283 aa) |
| | BCAP31 | B cell receptor associated protein 31. (246 aa) |
| | RNF14 | RBR-type E3 ubiquitin transferase. (474 aa) |
