STRINGSTRING
PIK3R6 PIK3R6 HGS HGS PLK2 PLK2 NFE2L2 NFE2L2 STAB1 STAB1 MAPK7 MAPK7 RTN4 RTN4 ACVRL1 ACVRL1 Brca1 Brca1 S100A1 S100A1 ISM1 ISM1 SERPINE1 SERPINE1 SH2B3 SH2B3 RAPGEF3 RAPGEF3 VASH2 VASH2 THBS1 THBS1 TGFB2 TGFB2 PIK3CB PIK3CB ITGB2 ITGB2 CYP1B1 CYP1B1 CCR2 CCR2 RRAS RRAS ENPP2 ENPP2 IL17F IL17F IL1B IL1B VEGFC VEGFC SFRP2 SFRP2 RHOJ RHOJ LOC101973790 LOC101973790 HK2 HK2 SEMA5A SEMA5A Itgb3 Itgb3 LRG1 LRG1 EPHA2 EPHA2 HGF HGF ANGPT2 ANGPT2 TBC1D31 TBC1D31 PRKCA PRKCA ITGAX ITGAX SLC12A2 SLC12A2 CXCL8 CXCL8 PRKD1 PRKD1 ADAM12 ADAM12 JMJD8 JMJD8 Xbp1 Xbp1 CNMD CNMD GRN GRN F3 F3 MINAR1 MINAR1 Hif1a Hif1a CCL24 CCL24 ANGPTL3 ANGPTL3 MTDH MTDH EPHA1 EPHA1 CCN6 CCN6 PROK1 PROK1 TIE1 TIE1 SPRED1 SPRED1 SP1 SP1 GATA2 GATA2 LIF LIF HHEX HHEX CDH5 CDH5 CXCR4 CXCR4 MMP9 MMP9 IL10 IL10 VEGFD VEGFD STARD13 STARD13 STAT3 STAT3 SPARC SPARC ID1 ID1 Faslg Faslg HPSE HPSE ITGA5 ITGA5 AGO2 AGO2 C6 C6 ENG ENG ECM1 ECM1 STAT1 STAT1 CXCR3 CXCR3 EFNA3 EFNA3 VEGFA VEGFA DCN DCN THBS4 THBS4 HSPB6 HSPB6 CELA1 CELA1 E2F2 E2F2 LOC101962660 LOC101962660 MYDGF MYDGF BMPER BMPER TNFRSF1A TNFRSF1A SEMA3E SEMA3E AKT3 AKT3 ATP2B4 ATP2B4 SMAD1 SMAD1 AGO1 AGO1 TNN TNN FOXJ2 FOXJ2 TJP1 TJP1 HOXA5 HOXA5 HTATIP2 HTATIP2 OPTC OPTC EMC10 EMC10 PLCG1 PLCG1 FUT1 FUT1 PRKCB PRKCB HRG HRG DDAH1 DDAH1 CREB3L1 CREB3L1 PPARG PPARG TNF TNF NODAL NODAL PDPK1 PDPK1 WARS2 WARS2 CXCR2 CXCR2 C5 C5 CTSH CTSH ISL1 ISL1 ITGB1 ITGB1 NRP1 NRP1 WARS1 WARS1 PML PML ATF2 ATF2 PXN PXN VEGFB VEGFB SYNJ2BP SYNJ2BP GLUL GLUL Rhob Rhob FKBPL FKBPL SLC39A12 SLC39A12 LOC101954665 LOC101954665 CAMP CAMP ERAP1 ERAP1 CHI3L1 CHI3L1 Aqp1 Aqp1 GHSR GHSR FBLN5 FBLN5 PDE3B PDE3B CTNNB1 CTNNB1 KDR KDR HYAL1 HYAL1 ITGB8 ITGB8 LOC101965906 LOC101965906 LEP LEP RNH1 RNH1 SHH SHH SIRT1 SIRT1 GPR4 GPR4 ALOX5 ALOX5 Fgf2 Fgf2 MDK MDK I3MV62_ICTTR I3MV62_ICTTR LOC101955809 LOC101955809 NAXE NAXE I3MVQ8_ICTTR I3MVQ8_ICTTR GAB1 GAB1 Spry2 Spry2 EMILIN1 EMILIN1 Ecscr Ecscr ADGRB1 ADGRB1 AGT AGT FOXC2 FOXC2 VASH1 VASH1 Notch4 Notch4 FLT1 FLT1 CD34 CD34 EMP2 EMP2 DLL1 DLL1 TAFA5 TAFA5 Znf304 Znf304 CLDN5 CLDN5 GATA6 GATA6 I3N2R3_ICTTR I3N2R3_ICTTR DAB2IP DAB2IP TERT TERT HSPB1 HSPB1 Egln1 Egln1 PTGIS PTGIS ROCK1 ROCK1 YJEFN3 YJEFN3 SULF1 SULF1 COL4A2 COL4A2 JAK1 JAK1 LOC101974597 LOC101974597 NINJ1 NINJ1 TBXA2R TBXA2R PGF PGF WNT5A WNT5A EPN1 EPN1 ANGPT4 ANGPT4 LOC101956215 LOC101956215 CCR3 CCR3 ANXA3 ANXA3 SERPINF1 SERPINF1 ZC3H12A ZC3H12A EMILIN2 EMILIN2 PTN PTN JCAD JCAD ADAMTS1 ADAMTS1 SPHK1 SPHK1 RGCC RGCC FGF1 FGF1 CX3CR1 CX3CR1 PLXND1 PLXND1 GREM1 GREM1 APLNR APLNR TLR3 TLR3 FGF18 FGF18 THBS2 THBS2 Aggf1 Aggf1 Pdcl3 Pdcl3 FOXO4 FOXO4 CYBB CYBB GDF2 GDF2 LGALS3 LGALS3 CD40 CD40 C5AR1 C5AR1 TNMD TNMD Hmga2 Hmga2 Gata4 Gata4 GHRL GHRL APOH APOH KLF4 KLF4 CXCL10 CXCL10 C3AR1 C3AR1 RAMP2 RAMP2 SEMA6A SEMA6A ENSSTOP00000024694 ENSSTOP00000024694 LOC101968118 LOC101968118 TGFBR2 TGFBR2 Apela Apela SIRT6 SIRT6 LOC101962934 LOC101962934 MECP2 MECP2 ADGRA2 ADGRA2 PTPRM PTPRM HMOX1 HMOX1 SMOC2 SMOC2 EPN2 EPN2 ADM ADM PDCD6 PDCD6 CRHR2 CRHR2 STIM1 STIM1 CCBE1 CCBE1 NF1 NF1 ADM2 ADM2 TNFRSF12A TNFRSF12A ENSSTOP00000027930 ENSSTOP00000027930 ADD1 ADD1 JUP JUP SARS1 SARS1 ETS1 ETS1 ENSSTOP00000029050 ENSSTOP00000029050 PPP1R16B PPP1R16B Pik3cd Pik3cd ENSSTOP00000030142 ENSSTOP00000030142 PTK2B PTK2B Krit1 Krit1 ADGRB3 ADGRB3 EFNA1 EFNA1 TEK TEK SEMA4A SEMA4A NOS3 NOS3 PKM PKM RECK RECK ADGRB2 ADGRB2 SASH1 SASH1 AMOT AMOT NR2E1 NR2E1 ABCC8 ABCC8 PRKD2 PRKD2 GTF2I GTF2I ROCK2 ROCK2 TSPAN12 TSPAN12
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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PIK3R6Phosphoinositide-3-kinase regulatory subunit 6. (748 aa)
HGSHepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (776 aa)
PLK2Serine/threonine-protein kinase PLK. (683 aa)
NFE2L2Nuclear factor, erythroid 2 like 2. (600 aa)
STAB1Stabilin 1. (2575 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (812 aa)
RTN4Reticulon. (1177 aa)
ACVRL1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (504 aa)
Brca1Uncharacterized protein. (353 aa)
S100A1Protein S100; Belongs to the S-100 family. (94 aa)
ISM1Isthmin 1. (464 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (402 aa)
SH2B3SH2B adaptor protein 3. (429 aa)
RAPGEF3Rap guanine nucleotide exchange factor 3. (898 aa)
VASH2Vasohibin 2. (355 aa)
THBS1Thrombospondin 1. (1182 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (442 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1070 aa)
ITGB2Integrin beta. (769 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (543 aa)
CCR2C-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (373 aa)
RRASRAS related. (218 aa)
ENPP2Ectonucleotide pyrophosphatase/phosphodiesterase 2. (915 aa)
IL17FInterleukin 17F. (161 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (200 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (417 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
RHOJRas homolog family member J. (214 aa)
LOC101973790Uncharacterized protein. (311 aa)
HK2Hexokinase 2. (917 aa)
SEMA5ASemaphorin 5A. (1074 aa)
Itgb3Integrin beta; Belongs to the integrin beta chain family. (792 aa)
LRG1Leucine rich alpha-2-glycoprotein 1. (354 aa)
EPHA2EPH receptor A2. (923 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (730 aa)
ANGPT2Angiopoietin 2. (495 aa)
TBC1D31TBC1 domain family member 31. (1068 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (603 aa)
ITGAXIntegrin subunit alpha X; Belongs to the integrin alpha chain family. (1171 aa)
SLC12A2Solute carrier family 12 member 2. (1108 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (843 aa)
ADAM12ADAM metallopeptidase domain 12. (840 aa)
JMJD8Jumonji domain containing 8. (256 aa)
Xbp1BZIP domain-containing protein. (351 aa)
CNMDChondromodulin. (334 aa)
GRNGranulin precursor. (596 aa)
F3Tissue factor; Initiates blood coagulation by forming a complex with circulating factor VII or VIIa. The [TF:VIIa] complex activates factors IX or X by specific limited proteolysis. TF plays a role in normal hemostasis by initiating the cell-surface assembly and propagation of the coagulation protease cascade. (293 aa)
MINAR1Membrane integral NOTCH2 associated receptor 1. (916 aa)
Hif1aUncharacterized protein. (821 aa)
CCL24C-C motif chemokine. (119 aa)
ANGPTL3Angiopoietin like 3. (455 aa)
MTDHMetadherin. (581 aa)
EPHA1EPH receptor A1. (978 aa)
CCN6Cellular communication network factor 6. (353 aa)
PROK1Prokineticin 1. (96 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1139 aa)
SPRED1Sprouty related EVH1 domain containing 1. (445 aa)
SP1Sp1 transcription factor. (788 aa)
GATA2GATA binding protein 2. (481 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
HHEXHematopoietically expressed homeobox. (272 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (784 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (352 aa)
MMP9Matrix metallopeptidase 9. (667 aa)
IL10Interleukin 10. (178 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (359 aa)
STARD13StAR related lipid transfer domain containing 13. (1120 aa)
STAT3Signal transducer and activator of transcription. (748 aa)
SPARCSecreted protein acidic and cysteine rich. (304 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (151 aa)
FaslgTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (69 aa)
HPSEHeparanase. (539 aa)
ITGA5Integrin subunit alpha 5; Belongs to the integrin alpha chain family. (1105 aa)
AGO2Protein argonaute-2; Required for RNA-mediated gene silencing (RNAi) by the RNA- induced silencing complex (RISC). The 'minimal RISC' appears to include AGO2 bound to a short guide RNA such as a microRNA (miRNA) or short interfering RNA (siRNA). These guide RNAs direct RISC to complementary mRNAs that are targets for RISC-mediated gene silencing. The precise mechanism of gene silencing depends on the degree of complementarity between the miRNA or siRNA and its target. Binding of RISC to a perfectly complementary mRNA generally results in silencing due to endonucleolytic cleavage of the [...] (862 aa)
C6Complement C6. (920 aa)
ENGEndoglin. (463 aa)
ECM1Extracellular matrix protein 1. (544 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
CXCR3C-X-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
EFNA3Ephrin RBD domain-containing protein; Belongs to the ephrin family. (210 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (392 aa)
DCNDecorin; May affect the rate of fibrils formation. (360 aa)
THBS4Thrombospondin 4. (961 aa)
HSPB6Heat shock protein family B (small) member 6; Belongs to the small heat shock protein (HSP20) family. (162 aa)
CELA1Chymotrypsin like elastase 1; Belongs to the peptidase S1 family. (266 aa)
E2F2E2F transcription factor 2. (432 aa)
LOC101962660Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (824 aa)
MYDGFMyeloid derived growth factor. (165 aa)
BMPERBMP binding endothelial regulator. (685 aa)
TNFRSF1ATNF receptor superfamily member 1A. (437 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (721 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
ATP2B4Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1214 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
AGO1Argonaute RISC component 1; Belongs to the argonaute family. (865 aa)
TNNTenascin N. (1561 aa)
FOXJ2Forkhead box J2. (574 aa)
TJP1Tight junction protein 1; Belongs to the MAGUK family. (1738 aa)
HOXA5Homeobox A5. (270 aa)
HTATIP2HIV-1 Tat interactive protein 2. (273 aa)
OPTCOpticin. (383 aa)
EMC10ER membrane protein complex subunit 10. (223 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1290 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (378 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (668 aa)
HRGHistidine rich glycoprotein. (531 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (285 aa)
CREB3L1cAMP responsive element binding protein 3 like 1. (519 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (505 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (233 aa)
NODALNodal growth differentiation factor. (350 aa)
PDPK13-phosphoinositide dependent protein kinase 1. (556 aa)
WARS2Tryptophanyl tRNA synthetase 2, mitochondrial; Belongs to the class-I aminoacyl-tRNA synthetase family. (360 aa)
CXCR2C-X-C motif chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (359 aa)
C5Complement C5. (1643 aa)
CTSHCathepsin H; Belongs to the peptidase C1 family. (335 aa)
ISL1ISL LIM homeobox 1. (349 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (798 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (923 aa)
WARS1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (475 aa)
PMLPromyelocytic leukemia. (877 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (504 aa)
PXNPaxillin; Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Belongs to the paxillin family. (424 aa)
VEGFBVascular endothelial growth factor B; Belongs to the PDGF/VEGF growth factor family. (184 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
GLULGlutamine synthetase. (373 aa)
RhobUncharacterized protein. (196 aa)
FKBPLFKBP prolyl isomerase like. (349 aa)
SLC39A12Solute carrier family 39 member 12. (692 aa)
LOC101954665C-X-C motif chemokine. (106 aa)
CAMPCathelicidin antimicrobial peptide. (171 aa)
ERAP1Aminopeptidase. (938 aa)
CHI3L1Chitinase 3 like 1; Belongs to the glycosyl hydrolase 18 family. (382 aa)
Aqp1Uncharacterized protein; Belongs to the MIP/aquaporin (TC 1.A.8) family. (269 aa)
GHSRGrowth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (366 aa)
FBLN5Fibulin 5. (411 aa)
PDE3BPhosphodiesterase. (1046 aa)
CTNNB1Catenin beta 1. (781 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1345 aa)
HYAL1Hyaluronidase. (449 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (768 aa)
LOC101965906Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (970 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
RNH1Ribonuclease/angiogenin inhibitor 1. (456 aa)
SHHSonic hedgehog signaling molecule. (370 aa)
SIRT1Sirtuin 1. (602 aa)
GPR4G protein-coupled receptor 4; Belongs to the G-protein coupled receptor 1 family. (362 aa)
ALOX5Arachidonate 5-lipoxygenase. (663 aa)
Fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (144 aa)
MDKMidkine. (143 aa)
I3MV62_ICTTRPhosducin domain-containing protein. (198 aa)
LOC101955809Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1335 aa)
NAXENAD(P)H-hydrate epimerase; Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX. (281 aa)
I3MVQ8_ICTTRUncharacterized protein. (110 aa)
GAB1GRB2 associated binding protein 1. (724 aa)
Spry2Uncharacterized protein. (315 aa)
EMILIN1Elastin microfibril interfacer 1. (1017 aa)
EcscrUncharacterized protein. (239 aa)
ADGRB1Adhesion G protein-coupled receptor B1; Belongs to the G-protein coupled receptor 2 family. (1453 aa)
AGTAngiotensinogen; Belongs to the serpin family. (477 aa)
FOXC2Forkhead box C2. (500 aa)
VASH1Vasohibin 1. (366 aa)
Notch4Uncharacterized protein. (1955 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1333 aa)
CD34CD34 molecule. (382 aa)
EMP2Epithelial membrane protein 2; Functions as a key regulator of cell membrane composition by regulating proteins surface expression. Also, plays a role in regulation of processes including cell migration, cell proliferation, cell contraction and cell adhesion; Belongs to the PMP-22/EMP/MP20 family. (167 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (715 aa)
TAFA5TAFA chemokine like family member 5. (125 aa)
Znf304Zinc finger protein 304. (616 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
GATA6GATA binding protein 6. (593 aa)
I3N2R3_ICTTRL-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (376 aa)
DAB2IPDAB2 interacting protein. (1148 aa)
TERTTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1079 aa)
HSPB1Heat shock protein family B (small) member 1; Belongs to the small heat shock protein (HSP20) family. (202 aa)
Egln1Fe2OG dioxygenase domain-containing protein. (127 aa)
PTGISProstaglandin I2 synthase; Belongs to the cytochrome P450 family. (414 aa)
ROCK1Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1368 aa)
YJEFN3YjeF N-terminal domain-containing protein. (249 aa)
SULF1Extracellular sulfatase; Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C- 6 position of glucosamine within specific subregions of intact heparin. Belongs to the sulfatase family. (869 aa)
COL4A2Collagen type IV alpha 2 chain. (1712 aa)
JAK1Tyrosine-protein kinase. (1142 aa)
LOC101974597L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (341 aa)
NINJ1Ninjurin 1. (127 aa)
TBXA2RThromboxane A2 receptor; Belongs to the G-protein coupled receptor 1 family. (343 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (170 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
EPN1Epsin 1. (576 aa)
ANGPT4Angiopoietin 4. (496 aa)
LOC101956215Uncharacterized protein. (195 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (359 aa)
ANXA3Annexin. (323 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (417 aa)
ZC3H12AZinc finger CCCH-type containing 12A. (599 aa)
EMILIN2Elastin microfibril interfacer 2. (1085 aa)
PTNPleiotrophin. (142 aa)
JCADJunctional cadherin 5 associated. (1363 aa)
ADAMTS1ADAM metallopeptidase with thrombospondin type 1 motif 1. (965 aa)
SPHK1Sphingosine kinase 1. (385 aa)
RGCCRegulator of cell cycle. (161 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (355 aa)
PLXND1Plexin D1. (1796 aa)
GREM1Gremlin. (184 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (380 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
THBS2Thrombospondin 2. (1173 aa)
Aggf1Uncharacterized protein. (717 aa)
Pdcl3Phosducin domain-containing protein. (240 aa)
FOXO4Forkhead box O4. (505 aa)
CYBBCytochrome b-245 beta chain. (549 aa)
GDF2Growth differentiation factor 2. (429 aa)
LGALS3Galectin. (220 aa)
CD40CD40 molecule. (284 aa)
C5AR1Complement C5a receptor 1; Belongs to the G-protein coupled receptor 1 family. (356 aa)
TNMDTenomodulin. (317 aa)
Hmga2Uncharacterized protein. (109 aa)
Gata4GATA-type domain-containing protein. (212 aa)
GHRLGhrelin and obestatin prepropeptide. (117 aa)
APOHApolipoprotein H. (306 aa)
KLF4Kruppel like factor 4. (485 aa)
CXCL10C-X-C motif chemokine. (98 aa)
C3AR1Complement C3a receptor 1; Belongs to the G-protein coupled receptor 1 family. (484 aa)
RAMP2Receptor activity modifying protein 2. (177 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1047 aa)
ENSSTOP00000024694Uncharacterized protein. (158 aa)
LOC101968118Uncharacterized protein; Belongs to the PI3/PI4-kinase family. (932 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (592 aa)
ApelaUncharacterized protein. (54 aa)
SIRT6Sirtuin 6. (351 aa)
LOC101962934Anti_prolifrtn domain-containing protein. (137 aa)
MECP2Methyl-CpG-binding protein 2; Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC). (486 aa)
ADGRA2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1335 aa)
PTPRMProtein tyrosine phosphatase receptor type M. (1507 aa)
HMOX1Heme oxygenase 1. (288 aa)
SMOC2SPARC related modular calcium binding 2. (446 aa)
EPN2Epsin 2. (648 aa)
ADMAdrenomedullin. (188 aa)
PDCD6Programmed cell death 6. (191 aa)
CRHR2Corticotropin releasing hormone receptor 2; Belongs to the G-protein coupled receptor 2 family. (436 aa)
STIM1Stromal interaction molecule 1. (716 aa)
CCBE1Collagen and calcium binding EGF domains 1. (290 aa)
NF1Neurofibromin 1. (2473 aa)
ADM2Adrenomedullin 2. (150 aa)
TNFRSF12ATNF receptor superfamily member 12A. (129 aa)
ENSSTOP00000027930Uncharacterized protein. (173 aa)
ADD1Adducin 1. (764 aa)
JUPJunction plakoglobin. (780 aa)
SARS1Seryl-tRNA synthetase. (514 aa)
ETS1ETS proto-oncogene 1, transcription factor. (441 aa)
ENSSTOP00000029050Uncharacterized protein. (117 aa)
PPP1R16BProtein phosphatase 1 regulatory subunit 16B. (568 aa)
Pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1045 aa)
ENSSTOP00000030142Uncharacterized protein. (409 aa)
PTK2BProtein tyrosine kinase 2 beta. (968 aa)
Krit1Uncharacterized protein. (736 aa)
ADGRB3Adhesion G protein-coupled receptor B3; Belongs to the G-protein coupled receptor 2 family. (1522 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (205 aa)
TEKTEK receptor tyrosine kinase. (1124 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (758 aa)
NOS3Nitric oxide synthase; Produces nitric oxide (NO). (1228 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (531 aa)
RECKReversion inducing cysteine rich protein with kazal motifs. (972 aa)
ADGRB2Adhesion G protein-coupled receptor B2; Belongs to the G-protein coupled receptor 2 family. (1582 aa)
SASH1SAM and SH3 domain containing 1. (1252 aa)
AMOTAngiomotin. (1068 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
ABCC8ATP binding cassette subfamily C member 8. (1624 aa)
PRKD2Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (878 aa)
GTF2IGeneral transcription factor IIi. (999 aa)
ROCK2Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1386 aa)
TSPAN12Tetraspanin. (305 aa)
Your Current Organism:
Ictidomys tridecemlineatus
NCBI taxonomy Id: 43179
Other names: Citellus tridecemlineatus, I. tridecemlineatus, Spermophilus tridecemlineatus, thirteen-lined ground squirrel
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